2,2'-Disulfanediyldiethanamine - 95%, high purity , CAS No.51-85-4

  • ≥95%
Item Number
D589340
Grouped product items
SKUSizeAvailabilityPrice Qty
D589340-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$46.90
D589340-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$125.90
D589340-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90

Basic Description

Synonymscystamine | Decarboxycystine | 2,2'-Dithiobis(ethylamine)
Specifications & Purity≥95%
Storage TempStore at 2-8°C,Protected from light,Argon charged
Shipped InWet ice
Product Description

Cystamine is the disulfide form of the free thiol, cysteamine. Cystamine is an orally active transglutaminase (Tgase) inhibitor. Cystamine also has inhibition activity for caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used for the research of severals diseases including Huntington's disease (HD).

Associated Targets(Human)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CEM-SS (2428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THPO Tbio Thrombopoietin (834 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

pol Human immunodeficiency virus type 1 protease (9113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pol Human immunodeficiency virus type 1 reverse transcriptase (18245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GST Glutathione S-transferase (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-(2-aminoethyldisulfanyl)ethanamine
INCHI InChI=1S/C4H12N2S2/c5-1-3-7-8-4-2-6/h1-6H2
InChi Key APQPRKLAWCIJEK-UHFFFAOYSA-N
Canonical SMILES C(CSSCCN)N
Isomeric SMILES C(CSSCCN)N
PubChem CID 2915
Molecular Weight 152.3

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot NumberCertificate TypeDateItem
F2411362Certificate of AnalysisMay 24, 2024 D589340
F2411363Certificate of AnalysisMay 24, 2024 D589340
F2411369Certificate of AnalysisMay 24, 2024 D589340
F2411372Certificate of AnalysisMay 24, 2024 D589340
K2404584Certificate of AnalysisMay 24, 2024 D589340
I2321184Certificate of AnalysisAug 02, 2023 D589340
I2321346Certificate of AnalysisAug 02, 2023 D589340

Chemical and Physical Properties

SensitivityLight sensitive

Related Documents

Citations of This Product

1. Kunxi Zhang, Yinan Zhu, Tao Wang, Dawei Niu, Zijie Xiahou, Hongzhong Wang, Peiliang Fu, Haiyan Cui, Jingbo Yin.  (2023)  Lubricating Micro-Interface Assisted General Strategy for Preparing dECM-Microparticle–Based Heterogeneous Granular Inks toward 3D Printing.  ADVANCED FUNCTIONAL MATERIALS,    (2307886).  [PMID:] [10.1002/adfm.202307886]
2. Ming Hao, Yanbo Liu, Zhijun Chen, Xiaodong Hu, Tianyi Zhang, Xinyu Zhu, Xingyu He, Bo Yang.  (2022)  Cross-Linked Gamma Polyglutamic Acid/Human Hair Keratin Electrospun Nanofibrous Scaffolds with Excellent Biocompatibility and Biodegradability.  Polymers,  14  (24): (5505).  [PMID:36559871] [10.3390/polym14245505]
3. Yimu Li, Xuling Chen, Jianbo Ji, Lingbing Li, Guangxi Zhai.  (2021)  Redox-responsive nanoparticles based on Chondroitin Sulfate and Docetaxel prodrug for tumor targeted delivery of Docetaxel.  CARBOHYDRATE POLYMERS,  255  (117393).  [PMID:33436222] [10.1016/j.carbpol.2020.117393]
4. Tehseen Nawaz, Muhammad Ahmad, Jieying Yu, Shiqi Wang, Tianxin Wei.  (2020)  The biomimetic detection of progesterone by novel bifunctional group monomer based molecularly imprinted polymers prepared in UV light.  NEW JOURNAL OF CHEMISTRY,  44  (17): (6992-7000).  [PMID:] [10.1039/C9NJ06387K]
5. Zhoujiang Chen, Zhanlin Zhang, Maohua Chen, Songzhi Xie, Tao Wang, Xiaohong Li.  (2019)  Synergistic antitumor efficacy of hybrid micelles with mitochondrial targeting and stimuli-responsive drug release behavior.  Journal of Materials Chemistry B,  (9): (1415-1426).  [PMID:32255012] [10.1039/C8TB02843E]
6. Guan-Hai Wang, Hua Chen, Yin-Yu Cai, Li Li, Hui-Kang Yang, Qin Li, Zhi-Jiang He, Jian-Tao Lin.  (2018)  Efficient gene vector with size changeable and nucleus targeting in cancer therapy.  Materials Science & Engineering C-Materials for Biological Applications,  90  (568).  [PMID:29853126] [10.1016/j.msec.2018.05.013]
7. Chunqi Zhu, Hanbo Zhang, Wei Li, Lihua Luo, Xiaomeng Guo, Zuhua Wang, Fenfen Kong, Qingpo Li, Jie Yang, Yongzhong Du, Jian You.  (2018)  Suppress orthotopic colon cancer and its metastasis through exact targeting and highly selective drug release by a smart nanomicelle.  BIOMATERIALS,  161  (144).  [PMID:29421551] [10.1016/j.biomaterials.2018.01.043]
8. Tang Xiuwen, Liu Sufang, Wang Sifeng, Zhang Qin, Cheng Zhiyi.  (2014)  Preparation of reversibly immobilized Jack bean urease on microchannel surface and application for enzyme inhibition assay.  Microfluidics and Nanofluidics,  17  (4): (721-728).  [PMID:] [10.1007/s10404-014-1360-8]

References

1. Kunxi Zhang, Yinan Zhu, Tao Wang, Dawei Niu, Zijie Xiahou, Hongzhong Wang, Peiliang Fu, Haiyan Cui, Jingbo Yin.  (2023)  Lubricating Micro-Interface Assisted General Strategy for Preparing dECM-Microparticle–Based Heterogeneous Granular Inks toward 3D Printing.  ADVANCED FUNCTIONAL MATERIALS,    (2307886).  [PMID:] [10.1002/adfm.202307886]
2. Ming Hao, Yanbo Liu, Zhijun Chen, Xiaodong Hu, Tianyi Zhang, Xinyu Zhu, Xingyu He, Bo Yang.  (2022)  Cross-Linked Gamma Polyglutamic Acid/Human Hair Keratin Electrospun Nanofibrous Scaffolds with Excellent Biocompatibility and Biodegradability.  Polymers,  14  (24): (5505).  [PMID:36559871] [10.3390/polym14245505]
3. Yimu Li, Xuling Chen, Jianbo Ji, Lingbing Li, Guangxi Zhai.  (2021)  Redox-responsive nanoparticles based on Chondroitin Sulfate and Docetaxel prodrug for tumor targeted delivery of Docetaxel.  CARBOHYDRATE POLYMERS,  255  (117393).  [PMID:33436222] [10.1016/j.carbpol.2020.117393]
4. Tehseen Nawaz, Muhammad Ahmad, Jieying Yu, Shiqi Wang, Tianxin Wei.  (2020)  The biomimetic detection of progesterone by novel bifunctional group monomer based molecularly imprinted polymers prepared in UV light.  NEW JOURNAL OF CHEMISTRY,  44  (17): (6992-7000).  [PMID:] [10.1039/C9NJ06387K]
5. Zhoujiang Chen, Zhanlin Zhang, Maohua Chen, Songzhi Xie, Tao Wang, Xiaohong Li.  (2019)  Synergistic antitumor efficacy of hybrid micelles with mitochondrial targeting and stimuli-responsive drug release behavior.  Journal of Materials Chemistry B,  (9): (1415-1426).  [PMID:32255012] [10.1039/C8TB02843E]
6. Guan-Hai Wang, Hua Chen, Yin-Yu Cai, Li Li, Hui-Kang Yang, Qin Li, Zhi-Jiang He, Jian-Tao Lin.  (2018)  Efficient gene vector with size changeable and nucleus targeting in cancer therapy.  Materials Science & Engineering C-Materials for Biological Applications,  90  (568).  [PMID:29853126] [10.1016/j.msec.2018.05.013]
7. Chunqi Zhu, Hanbo Zhang, Wei Li, Lihua Luo, Xiaomeng Guo, Zuhua Wang, Fenfen Kong, Qingpo Li, Jie Yang, Yongzhong Du, Jian You.  (2018)  Suppress orthotopic colon cancer and its metastasis through exact targeting and highly selective drug release by a smart nanomicelle.  BIOMATERIALS,  161  (144).  [PMID:29421551] [10.1016/j.biomaterials.2018.01.043]
8. Tang Xiuwen, Liu Sufang, Wang Sifeng, Zhang Qin, Cheng Zhiyi.  (2014)  Preparation of reversibly immobilized Jack bean urease on microchannel surface and application for enzyme inhibition assay.  Microfluidics and Nanofluidics,  17  (4): (721-728).  [PMID:] [10.1007/s10404-014-1360-8]

Solution Calculators