Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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D609117-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,400.90 | |
D609117-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,000.90 |
Specifications & Purity | Moligand™ |
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Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of casein kinase 1 gamma 1;Inhibitor of checkpoint kinase 1;Inhibitor of MAPK activated protein kinase 2;Inhibitor of protein kinase A;Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of ribosomal protein S6 kinase A |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-[[3,4-dioxo-2-(pyridin-4-ylamino)cyclobuten-1-yl]amino]-2-(3-hydroxyphenyl)acetamide |
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INCHI | InChI=1S/C17H14N4O4/c18-17(25)12(9-2-1-3-11(22)8-9)21-14-13(15(23)16(14)24)20-10-4-6-19-7-5-10/h1-8,12,21-22H,(H2,18,25)(H,19,20) |
InChi Key | GPXKVULNYYNGDP-UHFFFAOYSA-N |
Canonical SMILES | Oc1cccc(c1)C(C(=O)N)NC1=C(C(=O)C1=O)Nc1ccncc1 |
Isomeric SMILES | C1=CC(=CC(=C1)O)C(C(=O)N)NC2=C(C(=O)C2=O)NC3=CC=NC=C3 |
PubChem CID | 25207521 |
1. Lovering F, Kirincich S, Wang W, Combs K, Resnick L, Sabalski JE, Butera J, Liu J, Parris K, Telliez JB. (2009) Identification and SAR of squarate inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2).. Bioorg Med Chem, 17 (9): (3342-51). [PMID:19364658] [10.1021/op500134e] |