2，3-Bis(4-hydroxyphenyl)propionitrile - ≥98%(HPLC), high purity , CAS No.1428-67-7, Agonist of Estrogen receptor-α;Agonist of Estrogen receptor-β

Item Number

B136090

• Synonyms: Divinyl sulfone, contains <650 ppm hydroquinone as inhibitor, 97% | SR-01000597601-2 | (+/-)-2,3-bis(4-hydroxyphenyl)propanenitrile | MFCD01695412 | UNII-52XWB8Q4V8 | Benzenepropanenitrile,4-hydroxy-a-(4-hydroxyphenyl)- | HB2489 | HMS3650I14 | 2,3-bis(4-h
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: 2,3-Bis(4-hydroxyphenyl)-propionitrile (Diarylprepionitrile, DPN) is an ERβ-selective agonist; IC50 = 15nM. DPN protects WT and ARKO mice and significantly decreases IL-1β following LPS treatment in young adult-derived microglia. PPT (Cat. No.H6036, ERa a
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of Estrogen receptor-α;Agonist of Estrogen receptor-β
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.