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2,3 cis-Piperidine dicarboxylic acid (cis PDA) - ≥98%, high purity , CAS No.46026-75-9

  • ≥98%
Item Number
P274660
Grouped product items
SKUSizeAvailabilityPrice Qty
P274660-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$95.90
P274660-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$384.90

Ionotropic receptor antagonist

Basic Description

Synonymscis-Piperidine-2,3-dicarboxylic acid|cis-PDA|46026-75-9|(+/-)-cis-Piperidine-2,3-dicarboxylic acid|cis-2,3-Piperidine dicarboxylic acid|(2S,3R)-Piperidine-2,3-dicarboxylic acid|Lopac0_000964|SCHEMBL730489|CHEMBL431504|DTXSID80963487|HMS3263A09|Tox21_50096
Specifications & Purity≥98%
Biochemical and Physiological MechanismsGeneral ionotropic receptor antagonist. Blocks NMDA, AMPA and kainate mediated responses. Also acts as a partial NMDA receptor agonist in the in vitro rat cerebellar cGMP model.
Storage TempStore at 2-8°C,Desiccated
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MPHOSPH8 Tbio M-phase phosphoprotein 8 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

BLM Tchem Bloom syndrome protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ARSA Tbio Arylsulfatase A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIN3A Tclin Glutamate receptor ionotropic, NMDA 3A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2S,3R)-piperidine-2,3-dicarboxylic acid
INCHI InChI=1S/C7H11NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h4-5,8H,1-3H2,(H,9,10)(H,11,12)/t4-,5+/m1/s1
InChi Key PTLWNCBCBZZBJI-UHNVWZDZSA-N
Canonical SMILES C1CC(C(NC1)C(=O)O)C(=O)O
Isomeric SMILES C1C[C@H]([C@H](NC1)C(=O)O)C(=O)O
PubChem CID 11957663
Molecular Weight 173.17

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water to 100 mM

Related Documents

References

1. Umino Y et al..  (2019)  Rod Photoresponse Kinetics Limit Temporal Contrast Sensitivity in Mesopic Vision..  J Neurosci,  39  (16): (3041-3056).  [PMID:30737308]

Solution Calculators