2,3 cis-Piperidine dicarboxylic acid (cis PDA) - ≥98%, high purity , CAS No.46026-75-9

  • ≥98%
Item Number
P274660
Grouped product items
SKUSizeAvailabilityPrice Qty
P274660-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$95.90
P274660-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$384.90

Ionotropic receptor antagonist

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Basic Description

Synonyms(+/-)-cis-Piperidine-2,3-dicarboxylic acid | cis-PDA | LP00964 | (?)-cis-Piperidine-2,3-dicarboxylic acid | EU-0100964 | SCHEMBL730489 | SR-01000075465 | NCGC00094265-02 | (2S,3R)-Piperidine-2,3-dicarboxylic acid | Tox21_500964 | (y)-cis-Piperidine-2,3-di
Specifications & Purity≥98%
Biochemical and Physiological MechanismsGeneral ionotropic receptor antagonist. Blocks NMDA, AMPA and kainate mediated responses. Also acts as a partial NMDA receptor agonist in the in vitro rat cerebellar cGMP model.
Storage TempStore at 2-8°C,Desiccated
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(Human)

ARSA Tbio Cerebroside-sulfatase (655 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BLM Tchem Bloom syndrome protein (4248 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MPHOSPH8 Tbio M-phase phosphoprotein 8 (656 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

pfk 6-phospho-1-fructokinase (7870 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor (6467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2S,3R)-piperidine-2,3-dicarboxylic acid
INCHI InChI=1S/C7H11NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h4-5,8H,1-3H2,(H,9,10)(H,11,12)/t4-,5+/m1/s1
InChi Key PTLWNCBCBZZBJI-UHNVWZDZSA-N
Canonical SMILES C1CC(C(NC1)C(=O)O)C(=O)O
Isomeric SMILES C1C[C@H]([C@H](NC1)C(=O)O)C(=O)O
PubChem CID 11957663
Molecular Weight 173.17

Certificates

C of A & Other Certificates(BSE/TSE, COO)

Chemical and Physical Properties

SolubilitySoluble in water to 100 mM

Related Documents

References

1. Umino Y et al..  (2019)  Rod Photoresponse Kinetics Limit Temporal Contrast Sensitivity in Mesopic Vision..  J Neurosci,  39  (16): (3041-3056).  [PMID:30737308]

Solution Calculators