| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| D357191-5mg | 5mg | 3 | $157.90 | |
| D357191-25mg | 25mg | 3 | $546.90 | |
| D357191-100mg | 100mg | 2 | $1,531.90 |
an anti-retroviral compound
| Synonyms | 2',3'-Dideoxy-3'-fluorouridine, 95% | 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione | 5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluoro-2-hydroxymethyltetrahydrofuran | 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2 |
|---|---|
| Specifications & Purity | ≥95% |
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | 2′,3′-Dideoxy-3′-fluorouridine exhibits anti-retrovirus activity. Product Introduction 2′,3′-Dideoxy-3′-fluorouridine (3′-fluoro-2′,3′-dideoxyuridine, FddUrd) is a fluorinated pyrimidine nucleoside analog of uridine. It has been studied extensively for its potential use as an antiviral agent against HIV. Application 2′,3′-Dideoxy-3′-fluorouridine can be used as a starting material in the synthesis of: 3′-fluoro 2′,3′-dideoxynucleoside analogs for in vitro antiviral activity studies. 3′-fluoro deoxyuridine monophosphate analogs as potential anti parasites. |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| Pubchem Sid | 504757528 |
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| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504757528 |
| IUPAC Name | 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| INCHI | InChI=1S/C9H11FN2O4/c10-5-3-8(16-6(5)4-13)12-2-1-7(14)11-9(12)15/h1-2,5-6,8,13H,3-4H2,(H,11,14,15)/t5-,6+,8+/m0/s1 |
| InChi Key | BKIUEHLYJFLWPK-SHYZEUOFSA-N |
| Canonical SMILES | C1C(C(OC1N2C=CC(=O)NC2=O)CO)F |
| Isomeric SMILES | C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)F |
| WGK Germany | 1 |
| PubChem CID | 162450 |
| Molecular Weight | 230.19 |
| Boil Point(°C) | 480.84° C (Predicted) |
|---|---|
| Melt Point(°C) | 184-188° C (lit.) |
| Molecular Weight | 230.190 g/mol |
| XLogP3 | -0.500 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 230.07 Da |
| Monoisotopic Mass | 230.07 Da |
| Topological Polar Surface Area | 78.900 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 346.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| Pictogram(s) | GHS08 |
|---|---|
| Signal | Warning |
| Hazard Statements | H341:Suspected of causing genetic defects |
| Precautionary Statements | P405:Store locked up. P501:Dispose of contents/container to ... P281:Use personal protective equipment as required. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. |
| WGK Germany | 1 |
| RIDADR | NONHforallmodesoftransport |
G2208374