2′,3′-Dideoxyuridine - 98%, high purity , CAS No.5983-09-5

  • ≥98%
Item Number
D119469
Grouped product items
SKUSizeAvailabilityPrice Qty
D119469-100mg
100mg
In stock
$215.90
D119469-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,940.90

Basic Description

Synonyms2',3'-Dideoxyuridine | 5983-09-5 | Uridine, 2',3'-dideoxy- | Dideoxyuridine | 2,3-Dideoxyuridine | 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione | 1-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | ddUrd | 2',3'-dideoxy uridine |
Specifications & Purity≥98%
Shipped InNormal
Note100mg卖完停产,不再备货
Product Description

Research tool for antiviral and anticancer studies.

Associated Targets(Human)

MT4 (17854 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Moloney murine leukemia virus (54 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 2 (5592 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
INCHI InChI=1S/C9H12N2O4/c12-5-6-1-2-8(15-6)11-4-3-7(13)10-9(11)14/h3-4,6,8,12H,1-2,5H2,(H,10,13,14)/t6-,8+/m0/s1
InChi Key BTOTXLJHDSNXMW-POYBYMJQSA-N
Canonical SMILES C1CC(OC1CO)N2C=CC(=O)NC2=O
Isomeric SMILES C1C[C@@H](O[C@@H]1CO)N2C=CC(=O)NC2=O
WGK Germany 3
PubChem CID 65161
Molecular Weight 212.2
Beilstein 750592

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Certificate of Analysis(COA)

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Lot NumberCertificate TypeDateItem
I1419139Certificate of AnalysisJul 14, 2022 D119469

Chemical and Physical Properties

Specific Rotation[α]+32.0°~ +35.0°(C=0.4%, H2O)
Melt Point(°C)127-129°C

Safety and Hazards(GHS)

WGK Germany 3

Related Documents

References

1. Y X Li,P A Coucke,N Paschoud,R O Mirimanoff.  (1997-01-01)  Cytotoxic interactions of 5-fluorouracil and nucleoside analogues in vitro..  Anticancer research,  17  ((1A)): (21-27).  [PMID:9066626]
2. Shane J Cross,John H Rodman,Jane C Lindsey,Brian L Robbins,Charles H Rose,Geoffrey J Yuen', "Lawrence J D'angelo".  (2009-03-14)  Abacavir and metabolite pharmacokinetics in HIV-1-infected children and adolescents..  Journal of acquired immune deficiency syndromes (1999),  51  ((1)): (54-59).  [PMID:19282779]
3. C McGuigan,P Bellevergue,H Sheeka,N Mahmood,A J Hay.  (1994-08-29)  Certain phosphoramidate derivatives of dideoxy uridine (ddU) are active against HIV and successfully by-pass thymidine kinase..  FEBS letters,  351  ((1)): (11-14).  [PMID:8076677]
4. Khalid J H Alzahrani,Juma A M Ali,Anthonius A Eze,Wan Limm Looi,Daniel N A Tagoe,Darren J Creek,Michael P Barrett,Harry P de Koning.  (2017-04-30)  Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy..  International journal for parasitology. Drugs and drug resistance,  ((2)): (206-226).  [PMID:28453984]

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