Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | 2,3-Dihydroxybenzoic acid | 303-38-8 | Pyrocatechuic acid | o-Pyrocatechuic acid | 2-Pyrocatechuic acid | 3-Hydroxysalicylic acid | Benzoic acid, 2,3-dihydroxy- | DOBK | Catecholcarboxylic acid | 2,3-Dihydroxybenzoicacid | DHBA | dihydroxybenzoic acid | 2,3 DHB | 2,3-DIHYDROXY-BEN |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | 2,3-Dihydroxybenzoic acid was found to be orally effective iron-chelating drug in hypertransfused rat model. It is monocatechol siderophore produced by Brucella abortus. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | 2,3-Dihydroxybenzoic acid was found to be orally effective iron-chelating drug in hypertransfused rat model. It is monocatechol siderophore produced by Brucella abortus. |
Associated Targets(Human)
SLC26A4 Tbio Pendrin (0 Activities)
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (0 Activities)
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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)
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MMP1 Tchem Interstitial collagenase (0 Activities)
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MMP9 Tchem Matrix metalloproteinase-9 (0 Activities)
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METAP2 Tchem Methionine aminopeptidase 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ALOX5 Tclin Arachidonate 5-lipoxygenase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MMP2 Tchem 72 kDa type IV collagenase (0 Activities)
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SELL Tchem L-selectin (0 Activities)
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SELE Tchem E-selectin (0 Activities)
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SELP Tclin P-selectin (0 Activities)
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ATXN2 Tbio Ataxin-2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ALB Tchem Serum albumin (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ARG1 Tchem Arginase-1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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NOS2 Tchem Nitric oxide synthase, inducible (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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KDM4A Tchem Lysine-specific demethylase 4A (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MMP3 Tchem Stromelysin-1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MMP8 Tchem Neutrophil collagenase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
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TYR Tclin Tyrosinase (717 Activities)
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ALB Tchem Serum albumin (2651 Activities)
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METAP2 Tchem Methionine aminopeptidase 2 (1512 Activities)
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MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)
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MMP8 Tchem Matrix metalloproteinase 8 (1942 Activities)
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SELL Tchem Leukocyte adhesion molecule-1 (145 Activities)
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MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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HL-60 (67320 Activities)
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HEK293 (82097 Activities)
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HeLa (62764 Activities)
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KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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ATXN2 Tbio Ataxin-2 (54410 Activities)
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SLC26A4 Tbio Pendrin (86 Activities)
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Associated Targets(non-human)
Sele Selectin E (1 Activities)
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Selp P-selectin (7 Activities)
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Nos2 Nitric oxide synthase, inducible (3573 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mmp2 Matrix metalloproteinase-2 (12 Activities)
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Mmp9 Matrix metalloproteinase 9 (38 Activities)
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HD1 Histone deacetylase (38 Activities)
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PC-12 (7051 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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lef Anthrax lethal factor (7585 Activities)
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ARG1 Arginase-1 (70 Activities)
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Names and Identifiers
| IUPAC Name | 2,3-dihydroxybenzoic acid |
|---|---|
| INCHI | InChI=1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11) |
| InChi Key | GLDQAMYCGOIJDV-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC(=C(C(=C1)O)O)C(=O)O |
| Isomeric SMILES | C1=CC(=C(C(=C1)O)O)C(=O)O |
| WGK Germany | 2 |
| RTECS | DG8576490 |
| PubChem CID | 19 |
| Molecular Weight | 154.12 |
| Beilstein | 2209120 |
| Reaxy-Rn | 2209117 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Melt Point(°C) | 204-206°C |
|---|
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 2 |
| RTECS | DG8576490 |
| Reaxy-Rn | 2209117 |
Related Documents
Citations of This Product
| 1. Dali Fu, Haodong Wang, Tan Wang, Chunming Xu, Yehua Han. (2023) Structural insights into variation of intramolecular acid site using phase transition experiments and computation. AICHE JOURNAL, 70 (4): (e18342). [PMID:] |
| 2. Xiaomei Yao, Yingbo Fang, Xiaochen Cui, Xian Cheng, Zixia Cheng. (2023) Dielectric Barrier Discharge Plasma Coupled with Cobalt Oxyhydroxide for Methylene Blue Degradation. Toxics, 11 (9): (763). [PMID:37755773] |
| 3. Fanghua Guo, Li Peng, Hua Xiong, Rong Tsao, Hua Zhang, Li Jiang, Yong Sun. (2023) Bioaccessibility and transport of lentil hull polyphenols in vitro, and their bioavailability and metabolism in rats. FOOD RESEARCH INTERNATIONAL, 167 (112634). [PMID:37087206] |
| 4. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [PMID:] |
References
| 1. Dali Fu, Haodong Wang, Tan Wang, Chunming Xu, Yehua Han. (2023) Structural insights into variation of intramolecular acid site using phase transition experiments and computation. AICHE JOURNAL, 70 (4): (e18342). [PMID:] |
| 2. Xiaomei Yao, Yingbo Fang, Xiaochen Cui, Xian Cheng, Zixia Cheng. (2023) Dielectric Barrier Discharge Plasma Coupled with Cobalt Oxyhydroxide for Methylene Blue Degradation. Toxics, 11 (9): (763). [PMID:37755773] |
| 3. Fanghua Guo, Li Peng, Hua Xiong, Rong Tsao, Hua Zhang, Li Jiang, Yong Sun. (2023) Bioaccessibility and transport of lentil hull polyphenols in vitro, and their bioavailability and metabolism in rats. FOOD RESEARCH INTERNATIONAL, 167 (112634). [PMID:37087206] |
| 4. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [PMID:] |