Grouped product items

SKU

Size

Availability

Price

Qty

t168933-10mg

10mg

In stock

$94.90

t168933-50mg

50mg

In stock

$355.90

T168933-250mg

250mg

In stock

$1,602.90

T168933-1g

In stock

$5,767.90

Basic Description

Synonyms	AC-35369 \| SR-01000597603 \| NSC-748799 \| Stilbene, 2,3',4,5'-tetramethoxy- \| trans-2,4,3'',5''-tetramethoxystilbene \| trans-2,4,3',5'-tetramethoxystilbene \| CS-5626 \| Glycon S-80 \| AS-71536 \| Trans-2,3',4,5'-tetramethoxystilbene \| (E)-4,5'-(ethene-1,2-diy
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Potent, selective CYP1B1 inhibitor (IC 50 values are 6, 300 and 3100 nM for 1B1, 1A1 and 1A2, respectively). Competitive inhibitor (K i = 3 nM). Anticancer activity in vitro . 2,3′,4,5′-Tetramethoxystilbene, also known as TMS, is a selective and competiti
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

CYP1B1 Tchem Cytochrome P450 1B1 (7 Activities)

Discover Target: CYP1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1A1 Tchem Cytochrome P450 1A1 (4 Activities)

Discover Target: CYP1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TYR Tclin Tyrosinase (717 Activities)

Discover Target: TYR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1B1 Tchem Cytochrome P450 1B1 (1148 Activities)

Discover Target: CYP1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SRC Tclin Tyrosine-protein kinase SRC (10310 Activities)

Discover Target: SRC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A1 Tchem Cytochrome P450 1A1 (1169 Activities)

Discover Target: CYP1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTK2 Tclin Focal adhesion kinase 1 (4730 Activities)

Discover Target: PTK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A549 (127892 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Col2 (437 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NCI-H460 (60772 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KB (17409 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAPK3 Tchem Mitogen-activated protein kinase; ERK1/ERK2 (651 Activities)

Discover Target: MAPK3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A549/TR (299 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	1-[(E)-2-(2,4-dimethoxyphenyl)ethenyl]-3,5-dimethoxybenzene
INCHI	InChI=1S/C18H20O4/c1-19-15-8-7-14(18(12-15)22-4)6-5-13-9-16(20-2)11-17(10-13)21-3/h5-12H,1-4H3/b6-5+
InChi Key	JDBCWSHYEQUBLW-AATRIKPKSA-N
Canonical SMILES	COC1=CC(=C(C=C1)C=CC2=CC(=CC(=C2)OC)OC)OC
Isomeric SMILES	COC1=CC(=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)OC)OC
PubChem CID	5354004
Molecular Weight	300.35

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number	Certificate Type	Date	Item
I2205259	Certificate of Analysis	Jun 25, 2022	t168933
I2205262	Certificate of Analysis	Jun 25, 2022	t168933
I2205425	Certificate of Analysis	Jun 25, 2022	t168933
I2205426	Certificate of Analysis	Jun 25, 2022	t168933

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Zhixiang Hu, Licheng Zhou, Long Li, Jingyao Liu, Hua-Yao Li, Boxiang Song, Jianbing Zhang, Jiang Tang, Huan Liu. (2023) Stabilization of PbS colloidal-quantum-dot gas sensors using atomic-ligand engineering. SENSORS AND ACTUATORS B-CHEMICAL, 388 (133850). [PMID:]
2. Xiaodie Deng, Jialin Li, Pengbin Lai, Silan Kuang, Jiaxiang Liu, Pengpeng Dai, Haiming Hua, Peng Dong, Yingjie Zhang, Yang Yang, Jinbao Zhao. (2023) Tailored interface composition improves the integrity of electrode/electrolyte interphases for high-voltage Ni-rich lithium metal batteries in a sulfolane-based electrolyte. CHEMICAL ENGINEERING JOURNAL, 465 (142907). [PMID:]
3. Wei-Hao Zhang, Han-Yan Luo, Jing Fang, Chen-Liang Zhao, Kam-Chun Chan, Yui-Man Chan, Cai-Xia Dong, Hu-Biao Chen, Zhong-Zhen Zhao, Song-Lin Li, Jun Xu. (2022) Impact of Sulfur Fumigation on Ginger: Chemical and Biological Evidence. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (39): (12577–12586). [PMID:36130944]
4. Junjun Yin, Xiaoqian Chen, Duo Wang. (2022) Purification of creosol applying green heterogeneous extraction technology. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 97 (10): (2945-2951). [PMID:]
5. Chong Chen, Fumin Li, Liangxin Zhu, Zhitao Shen, Yujuan Weng, Qiang Lou, Furui Tan, Gentian Yue, Qingsong Huang, Mingtai Wang. (2020) Efficient and stable perovskite solar cells thanks to dual functions of oleyl amine-coated PbSO4(PbO)4 quantum dots: Defect passivation and moisture/oxygen blocking. Nano Energy, 68 (104313). [PMID:]
6. Junjie Bao, Gaojian Shi, Can Tao, Chao Wang, Chen Zhu, Liang Cheng, Gang Qian, Chunhua Chen. (2018) Polycarbonate-based polyurethane as a polymer electrolyte matrix for all-solid-state lithium batteries. JOURNAL OF POWER SOURCES, 389 (84). [PMID:]
7. Lunqiang Jin, Feng Liang. (2018) A Facile One-Pot Construction of Succinimide-Fused Spiro[Pyrrolidine-2,3′-Oxindoles] via 1,3-Dipolar Cycloaddition Involving 3-Amino Oxindoles and Maleimides. MOLECULES, 23 (3): (582). [PMID:29510590]
8. Chai Ran, Chen Yafei, Yuan Hongbo, Wang Xuzhao, Guo Shuai, Qi Jinlong, Zhang Hailin, Zhan Yong, An Hailong. (2017) Identification of Resveratrol, an Herbal Compound, as an Activator of the Calcium-Activated Chloride Channel, TMEM16A. JOURNAL OF MEMBRANE BIOLOGY, 250 (5): (483-492). [PMID:28852814]

References

1. Rentas S et al.. (2016) Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells.. Nature, 532 (7600): (508-511). [PMID:27121842]
2. Zhixiang Hu, Licheng Zhou, Long Li, Jingyao Liu, Hua-Yao Li, Boxiang Song, Jianbing Zhang, Jiang Tang, Huan Liu. (2023) Stabilization of PbS colloidal-quantum-dot gas sensors using atomic-ligand engineering. SENSORS AND ACTUATORS B-CHEMICAL, 388 (133850). [PMID:]
3. Xiaodie Deng, Jialin Li, Pengbin Lai, Silan Kuang, Jiaxiang Liu, Pengpeng Dai, Haiming Hua, Peng Dong, Yingjie Zhang, Yang Yang, Jinbao Zhao. (2023) Tailored interface composition improves the integrity of electrode/electrolyte interphases for high-voltage Ni-rich lithium metal batteries in a sulfolane-based electrolyte. CHEMICAL ENGINEERING JOURNAL, 465 (142907). [PMID:]
4. Wei-Hao Zhang, Han-Yan Luo, Jing Fang, Chen-Liang Zhao, Kam-Chun Chan, Yui-Man Chan, Cai-Xia Dong, Hu-Biao Chen, Zhong-Zhen Zhao, Song-Lin Li, Jun Xu. (2022) Impact of Sulfur Fumigation on Ginger: Chemical and Biological Evidence. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (39): (12577–12586). [PMID:36130944]
5. Junjun Yin, Xiaoqian Chen, Duo Wang. (2022) Purification of creosol applying green heterogeneous extraction technology. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 97 (10): (2945-2951). [PMID:]
6. Chong Chen, Fumin Li, Liangxin Zhu, Zhitao Shen, Yujuan Weng, Qiang Lou, Furui Tan, Gentian Yue, Qingsong Huang, Mingtai Wang. (2020) Efficient and stable perovskite solar cells thanks to dual functions of oleyl amine-coated PbSO4(PbO)4 quantum dots: Defect passivation and moisture/oxygen blocking. Nano Energy, 68 (104313). [PMID:]
7. Junjie Bao, Gaojian Shi, Can Tao, Chao Wang, Chen Zhu, Liang Cheng, Gang Qian, Chunhua Chen. (2018) Polycarbonate-based polyurethane as a polymer electrolyte matrix for all-solid-state lithium batteries. JOURNAL OF POWER SOURCES, 389 (84). [PMID:]
8. Lunqiang Jin, Feng Liang. (2018) A Facile One-Pot Construction of Succinimide-Fused Spiro[Pyrrolidine-2,3′-Oxindoles] via 1,3-Dipolar Cycloaddition Involving 3-Amino Oxindoles and Maleimides. MOLECULES, 23 (3): (582). [PMID:29510590]
9. Chai Ran, Chen Yafei, Yuan Hongbo, Wang Xuzhao, Guo Shuai, Qi Jinlong, Zhang Hailin, Zhan Yong, An Hailong. (2017) Identification of Resveratrol, an Herbal Compound, as an Activator of the Calcium-Activated Chloride Channel, TMEM16A. JOURNAL OF MEMBRANE BIOLOGY, 250 (5): (483-492). [PMID:28852814]

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2,4,3′,5′-tetramethoxystilbene - 98% (HPLC), high purity , CAS No.24144-92-1

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator