F2229391Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | 3-(3-(2-(4-Chlorophenylsulfonamido)ethyl)-5-(4-fluorobenzyl)phenyl)propanoic acid | EC 202-440-0 | W-109655 | 4-Amino-1,3-xylene | NSC 7640 | STK387111 | 1071170-27-8 | 4-Amino-m-xylene | AI3-16558 | asym-m-xylidene | 2,4-Dimethylaniline, >=99% | 2,4-XYLI |
|---|---|
| Specifications & Purity | analytical standard |
| Storage Temp | Protected from light |
| Shipped In | Normal |
| Grade | analytical standard |
Associated Targets(Human)
CBX1 Tbio Chromobox protein homolog 1 (0 Activities)
PPARD Tchem Peroxisome proliferator-activated receptor delta (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Associated Targets(non-human)
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Plasmodium falciparum (966862 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 2,4-dimethylaniline |
|---|---|
| INCHI | InChI=1S/C8H11N/c1-6-3-4-8(9)7(2)5-6/h3-5H,9H2,1-2H3 |
| InChi Key | CZZZABOKJQXEBO-UHFFFAOYSA-N |
| Canonical SMILES | CC1=CC(=C(C=C1)N)C |
| Isomeric SMILES | CC1=CC(=C(C=C1)N)C |
| WGK Germany | 2 |
| RTECS | ZE8925000 |
| PubChem CID | 7250 |
| UN Number | 1711 |
| Packing Group | II |
| Molecular Weight | 121.18 |
| Beilstein | 636243 |
| Reaxy-Rn | 636243 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Sensitivity | Light sensitive. |
|---|---|
| Refractive Index | 1.558 |
| Flash Point(°F) | 208.4 °F |
| Flash Point(°C) | 98 °C |
| Boil Point(°C) | 218°C |
| Melt Point(°C) | -14.3°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS06, GHS08, GHS09, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H319:Causes serious eye irritation H301:Toxic if swallowed H311:Toxic in contact with skin H331:Toxic if inhaled H373:Causes damage to organs through prolonged or repeated exposure H411:Toxic to aquatic life with long lasting effects H330:Fatal if inhaled |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P391:Collect spillage. P330:Rinse mouth. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell. |
| WGK Germany | 2 |
| RTECS | ZE8925000 |
| Reaxy-Rn | 636243 |
| Class | 6.1 |
| Merck Index | 10084 |
Related Documents
Citations of This Product
| 1. Jia Li, Changfan He, Xingtao Cao, Hong Sui, Xingang Li, Lin He. (2021) Low temperature thermal desorption-chemical oxidation hybrid process for the remediation of organic contaminated model soil: A case study. JOURNAL OF CONTAMINANT HYDROLOGY, 243 (103908). [PMID:34717180] [10.1016/j.jconhyd.2021.103908] |
| 2. Mengke Jia, Haina Hu, Xiaoqing Xiong, Lihua Lyu, Hongjuan Zhao, Shubiao Zhang, Jun Hou. (2021) Investigation on the construction, photophysical properties and dyeing mechanism of 1,8-naphthalimide-based fluorescent dyes suitable for dyeing wool fibers in supercritical CO2. DYES AND PIGMENTS, 190 (109343). [PMID:] [10.1016/j.dyepig.2021.109343] |
| 3. Xue Xiong, Meiling Qi. (2020) Adenine-functionalized polypropylene glycol: A novel stationary phase for gas chromatography offering good inertness for acids and bases combined with a unique selectivity. JOURNAL OF CHROMATOGRAPHY A, 1612 (460627). [PMID:31668867] [10.1016/j.chroma.2019.460627] |
| 4. Jinxia Xu, Fanyong Yan, Xiaodong Sun, Zhaoxu Wang. (2019) Effect of electron-donating/withdrawing substituents on the fluorescence of aniline containing fluorescein Schiff base derivatives. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 382 (111938). [PMID:] [10.1016/j.jphotochem.2019.111938] |
| 5. Mingming Liu, Xin Zhou, Yingyi Chen, Hanlan Liu, Xionghan Feng, Guohong Qiu, Fan Liu, Zhaorui Zeng. (2010) Innovative chemically bonded ionic liquids-based sol–gel coatings as highly porous, stable and selective stationary phases for solid phase microextraction. ANALYTICA CHIMICA ACTA, 683 (96). [PMID:21094387] [10.1016/j.aca.2010.10.004] |
References
| 1. T Nohmi,R Miyata,K Yoshikawa,M Nakadate,M Ishidate. (1983-02-15) Metabolic activation of 2,4-xylidine and its mutagenic metabolite.. Biochemical pharmacology, 32 ((4)): (735-738). [PMID:6338882] |
| 2. C Gopinath,D E Prentice,A E Street,D Crook. (1980-01-01) Serum bile acid concentration in some experimental liver lesions of rat.. Toxicology, 15 ((2)): (113-127). [PMID:7376190] |
| 3. S Göb,E Oliveros,S H Bossmann,A M Braun,C A Nascimento,R Guardani. (2001-11-07) Optimal experimental design and artificial neural networks applied to the photochemically enhanced Fenton reaction.. Water science and technology : a journal of the International Association on Water Pollution Research, 44 ((5)): (339-345). [PMID:11695480] |
| 4. Usha John,K P R Nair. (2004-07-14) Liquid phase overtone spectral investigations of 2,6-dimethylaniline and 2,4-dimethylaniline-evidence for steric nature of the ortho effect and the consequent base weakening.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 60 ((10)): (2337-2341). [PMID:15249023] |
| 5. R D Brimecombe,J L Limson. (2006-10-13) Electrochemical investigation of the effect of pH and solvent on amitraz stability.. Journal of agricultural and food chemistry, 54 ((21)): (8139-8143). [PMID:17032021] |
| 6. R D Brimecombe,R Fogel,J L Limson. (2006-11-09) Electrochemical monitoring of the biodegradation of 2,4-dimethylaniline.. Journal of agricultural and food chemistry, 54 ((23)): (8799-8803). [PMID:17090125] |
| 7. Haiyan Xu,Thomas M Heinze,Siwei Chen,Carl E Cerniglia,Huizhong Chen. (2007-10-16) Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora.. Applied and environmental microbiology, 73 ((23)): (7759-7762). [PMID:17933925] |
| 8. Ee Lui Ang,Jeffrey P Obbard,Huimin Zhao. (2008-09-25) Directed evolution of aniline dioxygenase for enhanced bioremediation of aromatic amines.. Applied microbiology and biotechnology, 81 ((6)): (1063-1070). [PMID:18813921] |
| 9. Robert J Strife,Michele L Mangels,Julie A Skare. (2009-09-08) Separation and analysis of dimethylaniline isomers by supercritical fluid chromatography--electrospray ionization tandem mass spectrometry.. Journal of chromatography. A, 1216 ((41)): (6970-6973). [PMID:19733358] |
| 10. Jin-Zhong Xu,Jian-Jun Miao,Hong Lin,Tao Ding,Zhen-Yun Zhao,Bin Wu,Chong-Yu Shen,Yuan Jiang. (2010-01-13) Determination of amitraz and 2,4-dimethylaniline residues in honey by using LC with UV detection and MS/MS.. Journal of separation science, 32 ((23-24)): (4020-4024). [PMID:20066677] |
| 11. Akito Takeuchi,Shinobu Yamamoto,Warren Hendricks,Yasuki Nishimura,Tsutoshi Imanaka,Yuichiro Kaifuku,Norihiro Sakui,Shuichiro Natsumeda,Hirokazu Ota,Shu Yamada,Ichiro Kurotani,Kimiaki Sumino,Seiichiro Kanno. (2011-03-23) Determination method for xylidines in workplace air.. Journal of occupational health, 53 ((3)): (230-233). [PMID:21422722] |
| 12. Stéphanie Romand,Julie Schappler,Jean-Luc Veuthey,Pierre-Alain Carrupt,Sophie Martel. (2014-07-06) cIEF for rapid pKa determination of small molecules: a proof of concept.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 63 (14-21). [PMID:24995703] |
| 13. Magdalena Markowicz-Piasecka,Elżbieta Mikiciuk-Olasik,Joanna Sikora. (2015-10-21) Stability of erythrocyte membrane and overall hemostasis potential - A biocompatibility study of mebrofenin and other iminodiacetic acid derivatives.. Pharmacological reports : PR, 67 ((6)): (1230-1239). [PMID:26481547] |
| 14. O Osano,A A Oladimeji,M H S Kraak,W Admiraal. (2002-06-05) Teratogenic effects of amitraz, 2,4-dimethylaniline, and paraquat on developing frog (Xenopus) embryos.. Archives of environmental contamination and toxicology, 43 ((1)): (42-49). [PMID:12045873] |
| 15. Stefan H Bossmann,Nabil Shahin,Hieu Le Thanh,Anna Bonfill,Michael Wörner,André M Braun. (2002-12-06) [FeII(bpy)3]2+/TiO2-codoped zeolites: synthesis, characterization, and first application in photocatalysis.. Chemphyschem : a European journal of chemical physics and physical chemistry, 3 ((5)): (401-407). [PMID:12465499] |
| 16. Ana M Amat,Antonio Arques,Stefan H Bossmann,André M Braun,Sabine Göb,Miguel A Miranda,Esther Oliveros. (2004-10-27) Oxidative degradation of 2,4-xylidine by photosensitization with 2,4,6-triphenylpyrylium: homogeneous and heterogeneous catalysis.. Chemosphere, 57 ((9)): (1123-1130). [PMID:15504471] |
| 17. Ee L Ang,Jeffrey P Obbard,Huimin Zhao. (2007-02-03) Probing the molecular determinants of aniline dioxygenase substrate specificity by saturation mutagenesis.. The FEBS journal, 274 ((4)): (928-939). [PMID:17269935] |
| 18. Nilgun Tokman,Carla Soler,Marinel la Farré,Yolanda Picó,Damià Barceló. (2009-02-24) Determination of amitraz and its transformation products in pears by ethyl acetate extraction and liquid chromatography-tandem mass spectrometry.. Journal of chromatography. A, 1216 ((15)): (3138-3146). [PMID:19232624] |
| 19. Huan Yu,Yanfei Tao,Tao Le,Dongmei Chen,Awais Ishsan,Yu Liu,Yulian Wang,Zonghui Yuan. (2010-06-18) Simultaneous determination of amitraz and its metabolite residue in food animal tissues by gas chromatography-electron capture detector and gas chromatography-mass spectrometry with accelerated solvent extraction.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878 ((21)): (1746-1752). [PMID:20554255] |
| 20. Jia Li, Changfan He, Xingtao Cao, Hong Sui, Xingang Li, Lin He. (2021) Low temperature thermal desorption-chemical oxidation hybrid process for the remediation of organic contaminated model soil: A case study. JOURNAL OF CONTAMINANT HYDROLOGY, 243 (103908). [PMID:34717180] [10.1016/j.jconhyd.2021.103908] |
| 21. Mengke Jia, Haina Hu, Xiaoqing Xiong, Lihua Lyu, Hongjuan Zhao, Shubiao Zhang, Jun Hou. (2021) Investigation on the construction, photophysical properties and dyeing mechanism of 1,8-naphthalimide-based fluorescent dyes suitable for dyeing wool fibers in supercritical CO2. DYES AND PIGMENTS, 190 (109343). [PMID:] [10.1016/j.dyepig.2021.109343] |
| 22. Xue Xiong, Meiling Qi. (2020) Adenine-functionalized polypropylene glycol: A novel stationary phase for gas chromatography offering good inertness for acids and bases combined with a unique selectivity. JOURNAL OF CHROMATOGRAPHY A, 1612 (460627). [PMID:31668867] [10.1016/j.chroma.2019.460627] |
| 23. Jinxia Xu, Fanyong Yan, Xiaodong Sun, Zhaoxu Wang. (2019) Effect of electron-donating/withdrawing substituents on the fluorescence of aniline containing fluorescein Schiff base derivatives. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 382 (111938). [PMID:] [10.1016/j.jphotochem.2019.111938] |
| 24. Mingming Liu, Xin Zhou, Yingyi Chen, Hanlan Liu, Xionghan Feng, Guohong Qiu, Fan Liu, Zhaorui Zeng. (2010) Innovative chemically bonded ionic liquids-based sol–gel coatings as highly porous, stable and selective stationary phases for solid phase microextraction. ANALYTICA CHIMICA ACTA, 683 (96). [PMID:21094387] [10.1016/j.aca.2010.10.004] |