Determine the necessary mass, volume, or concentration for preparing a solution.
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Synonyms | 2,5-DIHYDROXYBENZOIC ACID | gentisic acid | 490-79-9 | Hydroquinonecarboxylic acid | Benzoic acid, 2,5-dihydroxy- | 5-Hydroxysalicylic acid | Gentisate | Gensigen | Gensigon | 2,5-Dioxybenzoic acid | 2,5-Dhba | Gentisinic acid | Salicylic acid, 5-hydroxy- | Carboxyhydroquinone | Kys |
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Specifications & Purity | 10mM in DMSO |
Storage Temp | Protected from light,Store at -80°C |
Shipped In | Ice chest + Ice pads |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2,5-dihydroxybenzoic acid |
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INCHI | InChI=1S/C7H6O4/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,8-9H,(H,10,11) |
InChi Key | WXTMDXOMEHJXQO-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=C(C=C1O)C(=O)O)O |
Isomeric SMILES | C1=CC(=C(C=C1O)C(=O)O)O |
WGK Germany | 3 |
RTECS | LY3850000 |
PubChem CID | 3469 |
Molecular Weight | 154.12 |
Beilstein | 10(4)1441 |
Reaxy-Rn | 2209119 |
Enter Lot Number to search for COA:
Melt Point(°C) | 200-205°C |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | LY3850000 |
Reaxy-Rn | 2209119 |
Merck Index | 4398 |
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39. Yitao Li, Xingdong Shi, Zhi Zhang, Yazhou Peng. (2019) Enhanced coagulation by high-frequency ultrasound in Microcystis aeruginosa-laden water: Strategies and mechanisms. ULTRASONICS SONOCHEMISTRY, 55 (232). [PMID:30712852] [10.1016/j.ultsonch.2019.01.022] |
40. Chen Xin, Tang Hongzhi, Liu Yongdi, Xu Ping, Xue Yong, Lin Kuangfei, Cui Changzheng. (2018) Purification and Initial Characterization of 3-Hydroxybenzoate 6-Hydroxylase From a Halophilic Martelella Strain AD-3. Frontiers in Microbiology, 9 (1335). [PMID:30034371] [10.3389/fmicb.2018.01335] |
41. Weixuan Wang, Yadong Hu, Changmei Yang, Songbiao Zhu, Xiaofei Wang, Zhenyu Zhang, Haiteng Deng. (2018) Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition *. MOLECULAR & CELLULAR PROTEOMICS, 17 (10): (2005-2017). [PMID:29980616] [10.1074/mcp.RA118.000882] |
42. Qiqin Wang, Huihui Wu, Kun Peng, Hanying Jin, Huikai Shao, Yuqiang Wang, Jacques Crommen, Zhengjin Jiang. (2018) Hydrophilic polymeric monoliths containing choline phosphate for separation science applications. ANALYTICA CHIMICA ACTA, 999 (184). [PMID:29254571] [10.1016/j.aca.2017.11.032] |
43. Lei Zhou, Zhiqiang Xiong, Wei Liu, Liqiang Zou. (2017) Different inhibition mechanisms of gentisic acid and cyaniding-3-O-glucoside on polyphenoloxidase. FOOD CHEMISTRY, 234 (445). [PMID:28551259] [10.1016/j.foodchem.2017.05.010] |
44. Dai Lili, Jin Shanxia, Fan Mengying, Zhou Ping. (2017) Preparation of quaternized cellulose/chitosan microspheres for selective enrichment of phosphopeptides. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 (13): (3309-3317). [PMID:28258465] [10.1007/s00216-017-0273-2] |
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46. Nan Lv, Zhigang Wang, Wenzhi Bi, Guangming Li, Jilin Zhang, Jiazuan Ni. (2016) C8-modified CeO2//SiO2 Janus fibers for selective capture and individual MS detection of low-abundance peptides and phosphopeptides. Journal of Materials Chemistry B, 4 (25): (4402-4409). [PMID:32263422] [10.1039/C6TB00476H] |
47. Zhiqiang Xiong, Wei Liu, Lei Zhou, Liqiang Zou, Jun Chen. (2016) Mushroom (Agaricus bisporus) polyphenoloxidase inhibited by apigenin: Multi-spectroscopic analyses and computational docking simulation. FOOD CHEMISTRY, 203 (430). [PMID:26948635] [10.1016/j.foodchem.2016.02.045] |
48. Xiaoming Zhang, Yuyang Tian, Jiangtao Jia, Tingting Zhang, Guangshan Zhu. (2016) Synthesis, characterization and dissolution of three pharmaceutical cocrystals based on deferiprone. JOURNAL OF MOLECULAR STRUCTURE, 1108 (560). [PMID:] [10.1016/j.molstruc.2015.12.055] |
49. Zhi-Gang Wang, Wen-Zhi Bi, Shu-Cui Ma, Nan Lv, Ji-Lin Zhang, De-Hui Sun, Jia-Zuan Ni. (2015) Facet-Dependent Effect of Well-Defined CeO2 Nanocrystals on the Adsorption and Dephosphorylation of Phosphorylated Molecules. PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, 32 (6): (652-660). [PMID:] [10.1002/ppsc.201400230] |
50. Zhi-Gang Wang, Gong Cheng, Yan-Lin Liu, Ji-Lin Zhang, De-Hui Sun, Jia-Zuan Ni. (2014) Novel core–shell Cerium(IV)-immobilized magnetic polymeric microspheres for selective enrichment and rapid separation of phosphopeptides. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 417 (217). [PMID:24407680] [10.1016/j.jcis.2013.11.004] |
51. Gong Cheng, Yan-Lin Liu, Zhi-Gang Wang, Ji-Lin Zhang, De-Hui Sun, Jia-Zuan Ni. (2012) The GO/rGO–Fe3O4 composites with good water-dispersibility and fast magnetic response for effective immobilization and enrichment of biomolecules. JOURNAL OF MATERIALS CHEMISTRY, 22 (41): (21998-22004). [PMID:] [10.1039/C2JM33695B] |
52. Cheng Gong, Liu Yan-Lin, Zhang Ji-Lin, Sun De-Hui, Ni Jia-Zuan. (2012) Lanthanum silicate coated magnetic microspheres as a promising affinity material for phosphopeptide enrichment and identification. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 404 (3): (763-770). [PMID:22722743] [10.1007/s00216-012-6150-0] |
53. Xina Cheng,Xueting Ye,Dan Liu,Nan Zhao,Huiyuan Gao,Ping Wang,Guangbo Ge,Xiaozhe Zhang. (2017-08-25) N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry.. Rapid communications in mass spectrometry : RCM, 31 ((21)): (1779-1784). [PMID:28838027] |
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19. Qiqin Wang, Lingjue Sun, Huihui Wu, Ning Deng, Xianglong Zhao, Jingwei Zhou, Tingting Zhang, Hai Han, Zhengjin Jiang. (2022) Rapid fabrication of zwitterionic sulfobetaine vinylimidazole-based monoliths via photoinitiated copolymerization for hydrophilic interaction chromatography. Journal of Pharmaceutical Analysis, 12 (783). [PMID:36320596] [10.1016/j.jpha.2022.05.008] |
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37. Lei Xu, Xiao Ma, Junfeng Niu, Jie Chen, Chengzhi Zhou. (2019) Removal of trace naproxen from aqueous solution using a laboratory-scale reactive flow-through membrane electrode. JOURNAL OF HAZARDOUS MATERIALS, 379 (120692). [PMID:31255850] [10.1016/j.jhazmat.2019.05.085] |
38. Liping Liu, Shanxia Jin, Pengcheng Mei, Ping Zhou. (2019) Preparation of cotton wool modified with boric acid functionalized titania for selective enrichment of glycopeptides. TALANTA, 203 (58). [PMID:31202350] [10.1016/j.talanta.2019.05.050] |
39. Yitao Li, Xingdong Shi, Zhi Zhang, Yazhou Peng. (2019) Enhanced coagulation by high-frequency ultrasound in Microcystis aeruginosa-laden water: Strategies and mechanisms. ULTRASONICS SONOCHEMISTRY, 55 (232). [PMID:30712852] [10.1016/j.ultsonch.2019.01.022] |
40. Chen Xin, Tang Hongzhi, Liu Yongdi, Xu Ping, Xue Yong, Lin Kuangfei, Cui Changzheng. (2018) Purification and Initial Characterization of 3-Hydroxybenzoate 6-Hydroxylase From a Halophilic Martelella Strain AD-3. Frontiers in Microbiology, 9 (1335). [PMID:30034371] [10.3389/fmicb.2018.01335] |
41. Weixuan Wang, Yadong Hu, Changmei Yang, Songbiao Zhu, Xiaofei Wang, Zhenyu Zhang, Haiteng Deng. (2018) Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition *. MOLECULAR & CELLULAR PROTEOMICS, 17 (10): (2005-2017). [PMID:29980616] [10.1074/mcp.RA118.000882] |
42. Qiqin Wang, Huihui Wu, Kun Peng, Hanying Jin, Huikai Shao, Yuqiang Wang, Jacques Crommen, Zhengjin Jiang. (2018) Hydrophilic polymeric monoliths containing choline phosphate for separation science applications. ANALYTICA CHIMICA ACTA, 999 (184). [PMID:29254571] [10.1016/j.aca.2017.11.032] |
43. Lei Zhou, Zhiqiang Xiong, Wei Liu, Liqiang Zou. (2017) Different inhibition mechanisms of gentisic acid and cyaniding-3-O-glucoside on polyphenoloxidase. FOOD CHEMISTRY, 234 (445). [PMID:28551259] [10.1016/j.foodchem.2017.05.010] |
44. Dai Lili, Jin Shanxia, Fan Mengying, Zhou Ping. (2017) Preparation of quaternized cellulose/chitosan microspheres for selective enrichment of phosphopeptides. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 (13): (3309-3317). [PMID:28258465] [10.1007/s00216-017-0273-2] |
45. Benguo Liu, Huizhi Xiao, Jiaqi Li, Sheng Geng, Hanjun Ma, Guizhao Liang. (2017) Interaction of phenolic acids with trypsin: Experimental and molecular modeling studies. FOOD CHEMISTRY, 228 (1). [PMID:28317701] [10.1016/j.foodchem.2017.01.126] |
46. Nan Lv, Zhigang Wang, Wenzhi Bi, Guangming Li, Jilin Zhang, Jiazuan Ni. (2016) C8-modified CeO2//SiO2 Janus fibers for selective capture and individual MS detection of low-abundance peptides and phosphopeptides. Journal of Materials Chemistry B, 4 (25): (4402-4409). [PMID:32263422] [10.1039/C6TB00476H] |
47. Zhiqiang Xiong, Wei Liu, Lei Zhou, Liqiang Zou, Jun Chen. (2016) Mushroom (Agaricus bisporus) polyphenoloxidase inhibited by apigenin: Multi-spectroscopic analyses and computational docking simulation. FOOD CHEMISTRY, 203 (430). [PMID:26948635] [10.1016/j.foodchem.2016.02.045] |
48. Xiaoming Zhang, Yuyang Tian, Jiangtao Jia, Tingting Zhang, Guangshan Zhu. (2016) Synthesis, characterization and dissolution of three pharmaceutical cocrystals based on deferiprone. JOURNAL OF MOLECULAR STRUCTURE, 1108 (560). [PMID:] [10.1016/j.molstruc.2015.12.055] |
49. Zhi-Gang Wang, Wen-Zhi Bi, Shu-Cui Ma, Nan Lv, Ji-Lin Zhang, De-Hui Sun, Jia-Zuan Ni. (2015) Facet-Dependent Effect of Well-Defined CeO2 Nanocrystals on the Adsorption and Dephosphorylation of Phosphorylated Molecules. PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, 32 (6): (652-660). [PMID:] [10.1002/ppsc.201400230] |
50. Zhi-Gang Wang, Gong Cheng, Yan-Lin Liu, Ji-Lin Zhang, De-Hui Sun, Jia-Zuan Ni. (2014) Novel core–shell Cerium(IV)-immobilized magnetic polymeric microspheres for selective enrichment and rapid separation of phosphopeptides. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 417 (217). [PMID:24407680] [10.1016/j.jcis.2013.11.004] |
51. Gong Cheng, Yan-Lin Liu, Zhi-Gang Wang, Ji-Lin Zhang, De-Hui Sun, Jia-Zuan Ni. (2012) The GO/rGO–Fe3O4 composites with good water-dispersibility and fast magnetic response for effective immobilization and enrichment of biomolecules. JOURNAL OF MATERIALS CHEMISTRY, 22 (41): (21998-22004). [PMID:] [10.1039/C2JM33695B] |
52. Cheng Gong, Liu Yan-Lin, Zhang Ji-Lin, Sun De-Hui, Ni Jia-Zuan. (2012) Lanthanum silicate coated magnetic microspheres as a promising affinity material for phosphopeptide enrichment and identification. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 404 (3): (763-770). [PMID:22722743] [10.1007/s00216-012-6150-0] |
53. Xina Cheng,Xueting Ye,Dan Liu,Nan Zhao,Huiyuan Gao,Ping Wang,Guangbo Ge,Xiaozhe Zhang. (2017-08-25) N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry.. Rapid communications in mass spectrometry : RCM, 31 ((21)): (1779-1784). [PMID:28838027] |