Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | 6-carboxy-nicotinic acid | 1189695-39-3 | AM20050593 | FG-0457 | SY007555 | F0001-0013 | 2,5-Pyridinedicarboxylic acid | AB00376873-03 | pyridine carboxylate, 6b | AKOS000119637 | NCGC00336418-01 | W-204355 | Pyridinedicarboxylic acid-(2,5) | PYRIDINE-2,5 |
|---|---|
| Specifications & Purity | ≥98% |
| Shipped In | Normal |
| Product Description | 2,5-Pyridinedicarboxylic acid is used to prepare new 2,5-pyridinedicarboxylic acid derivatives as antiviral agents. 2,5-Pyridinedicarboxylic acid can be used: • In the synthesis of diorganotin(IV) 2,5-pyridinedicarboxylates. • In the preparation of three-dimensional coordination polymers of lanthanide 2,5-pyridinedicarboxylates by hydrothermal method. • As an organocatalyst in the synthesis of 1,5-benzodiazepine derivatives via one pot three-component reaction. |
Associated Targets(Human)
EGLN1 Tclin Egl nine homolog 1 (0 Activities)
EGLN3 Tclin Egl nine homolog 3 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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EGLN2 Tclin Egl nine homolog 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MMP1 Tchem Interstitial collagenase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MMP9 Tchem Matrix metalloproteinase-9 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ALOX5 Tclin Arachidonate 5-lipoxygenase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MMP2 Tchem 72 kDa type IV collagenase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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P4HA1 Tchem Prolyl 4-hydroxylase subunit alpha-1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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P4HTM Tchem Transmembrane prolyl 4-hydroxylase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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NOS2 Tchem Nitric oxide synthase, inducible (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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KDM4E Tchem Lysine-specific demethylase 4E (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MMP3 Tchem Stromelysin-1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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MMP8 Tchem Neutrophil collagenase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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TYR Tclin Tyrosinase (717 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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EGLN2 Tclin Hypoxia-inducible factor prolyl hydroxylase 1 (404 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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MMP8 Tchem Matrix metalloproteinase 8 (1942 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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P4HTM Tchem Hypoxia-inducible factor prolyl 4-hydroxylase (111 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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EGLN1 Tclin Egl nine homolog 1 (1702 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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EGLN3 Tclin Egl nine homolog 3 (250 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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P4HA1 Tchem Prolyl 4-hydroxylase subunit alpha-1 (16 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
blaZ Beta-lactamase (285 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Nos2 Nitric oxide synthase, inducible (3573 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mmp2 Matrix metalloproteinase-2 (12 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mmp9 Matrix metalloproteinase 9 (38 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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P4ha1 Prolyl 4-hydroxylase alpha-1 subunit (36 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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lef Anthrax lethal factor (7585 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Beta-lactamase L1 (242 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| Pubchem Sid | 488180462 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488180462 |
| IUPAC Name | pyridine-2,5-dicarboxylic acid |
| INCHI | InChI=1S/C7H5NO4/c9-6(10)4-1-2-5(7(11)12)8-3-4/h1-3H,(H,9,10)(H,11,12) |
| InChi Key | LVPMIMZXDYBCDF-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC(=NC=C1C(=O)O)C(=O)O |
| Isomeric SMILES | C1=CC(=NC=C1C(=O)O)C(=O)O |
| WGK Germany | 3 |
| PubChem CID | 7493 |
| Molecular Weight | 167.12 |
| Beilstein | 131697 |
| Reaxy-Rn | 131697 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 A2411005 | Certificate of Analysis | Aug 08, 2022 | P106867 |
| D2324720 | Certificate of Analysis | Aug 08, 2022 | P106867 |
| D2426043 | Certificate of Analysis | Aug 08, 2022 | P106867 |
| I2214246 | Certificate of Analysis | Aug 08, 2022 | P106867 |
| I2214248 | Certificate of Analysis | Aug 08, 2022 | P106867 |
| I2214251 | Certificate of Analysis | Aug 08, 2022 | P106867 |
| J2429111 | Certificate of Analysis | Aug 08, 2022 | P106867 |
| J2429112 | Certificate of Analysis | Aug 08, 2022 | P106867 |
Chemical and Physical Properties
| Melt Point(°C) | 254 °C |
|---|
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |
| WGK Germany | 3 |
| Reaxy-Rn | 131697 |
| Merck Index | 5159 |
Related Documents
Citations of This Product
| 1. Zhiyuan Liu, Linmeng Wang, Changan Wang, Rushuo Li, Peiyun Zhou, Hongyi Gao, Ge Wang. (2024) Modulating the strong metal-support interactions by regulating the chemical microenvironment of Pt confined in MOFs for low temperature hydrogenation of DCPD. CHEMICAL ENGINEERING JOURNAL, 479 (147601). [PMID:] [10.1016/j.cej.2023.147601] |
| 2. Li-Qiong He, Zhi-Mei Wang, Yu-Jie Li, Jing Yang, Li-Fu Liao, Xi-Lin Xiao, Yong Liu. (2022) A Novel Electrochemical Sensor Modified with a Computer-Simulative Magnetic Ion-Imprinted Membrane for Identification of Uranyl Ion. SENSORS, 22 (12): (4410). [PMID:35746190] [10.3390/s22124410] |
| 3. Shengnan Yin, Changlun Tong. (2021) Europium(III)-Modified Silver Nanoparticles as Ratiometric Colorimetric and Fluorescent Dual-Mode Probes for Selective Detection of Dipicolinic Acid in Bacterial Spores and Lake Waters. ACS Applied Nano Materials, 4 (5): (5469–5477). [PMID:] [10.1021/acsanm.1c00838] |
| 4. Ru-Ru Gao, Wei Dong. (2021) ATP and lanthanide ions derived coordination polymer nanoparticles as a novel family of versatile materials: Color-tunable emission, artificial tongues and logic devices. MICROCHEMICAL JOURNAL, 160 (105753). [PMID:] [10.1016/j.microc.2020.105753] |
| 5. Guo-Cheng Liu, Yan Li, Ying Xiong, Xiang-Xiang Liu, Qiao-Min Li, Ju-Wen Zhang, Hong-Yan Lin, Xiao-Wu Li. (2018) Spacers-directed structural diversity of Co(II)/Zn(II) complexes based on S-/O-bridged dipyridylamides: electrochemical, fluorescent recognition behavior and photocatalytic properties. JOURNAL OF COORDINATION CHEMISTRY, [PMID:] [10.1080/00958972.2018.1438606] |
References
| 1. Rose NR, Ng SS, Mecinović J, Liénard BM, Bello SH, Sun Z, McDonough MA, Oppermann U, Schofield CJ. (2008) Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.. J Med Chem, 51 (22): (7053-6). [PMID:18942826] [10.1021/op500134e] |
| 2. L E Horsfall,G Garau,B M R Liénard,O Dideberg,C J Schofield,J M Frère,M Galleni. (2007-02-20) Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila.. Antimicrobial agents and chemotherapy, 51 ((6)): (2136-2142). [PMID:17307979] |
| 3. Jennifer A Jacobsen,Jessica L Fullagar,Melissa T Miller,Seth M Cohen. (2010-12-30) Identifying chelators for metalloprotein inhibitors using a fragment-based approach.. Journal of medicinal chemistry, 54 ((2)): (591-602). [PMID:21189019] |
| 4. Debal Kanti Singha,Partha Mahata. (2017-08-16) Coordination polymer-derived nano-sized zinc ferrite with excellent performance in nitro-explosive detection.. Dalton transactions (Cambridge, England : 2003), 46 ((34)): (11344-11354). [PMID:28809982] |
| 5. Athanasios Koutsianos,Ewa Kazimierska,Andrew R Barron,Marco Taddei,Enrico Andreoli. (2019-02-20) A new approach to enhancing the CO2 capture performance of defective UiO-66 via post-synthetic defect exchange.. Dalton transactions (Cambridge, England : 2003), 48 ((10)): (3349-3359). [PMID:30778497] |
| 6. Noemí Contreras-Pereda,Faezeh Moghzi,Javier Baselga,Haixia Zhong,Jan Janczak,Janet Soleimannejad,Renhao Dong,Daniel Ruiz-Molina. (2020-08-05) Ultrasound-assisted exfoliation of a layered 2D coordination polymer with HER electrocatalytic activity.. Ultrasonics sonochemistry, 70 (105292-105292). [PMID:32750659] |
| 7. Zhiyuan Liu, Linmeng Wang, Changan Wang, Rushuo Li, Peiyun Zhou, Hongyi Gao, Ge Wang. (2024) Modulating the strong metal-support interactions by regulating the chemical microenvironment of Pt confined in MOFs for low temperature hydrogenation of DCPD. CHEMICAL ENGINEERING JOURNAL, 479 (147601). [PMID:] [10.1016/j.cej.2023.147601] |
| 8. Li-Qiong He, Zhi-Mei Wang, Yu-Jie Li, Jing Yang, Li-Fu Liao, Xi-Lin Xiao, Yong Liu. (2022) A Novel Electrochemical Sensor Modified with a Computer-Simulative Magnetic Ion-Imprinted Membrane for Identification of Uranyl Ion. SENSORS, 22 (12): (4410). [PMID:35746190] [10.3390/s22124410] |
| 9. Shengnan Yin, Changlun Tong. (2021) Europium(III)-Modified Silver Nanoparticles as Ratiometric Colorimetric and Fluorescent Dual-Mode Probes for Selective Detection of Dipicolinic Acid in Bacterial Spores and Lake Waters. ACS Applied Nano Materials, 4 (5): (5469–5477). [PMID:] [10.1021/acsanm.1c00838] |
| 10. Ru-Ru Gao, Wei Dong. (2021) ATP and lanthanide ions derived coordination polymer nanoparticles as a novel family of versatile materials: Color-tunable emission, artificial tongues and logic devices. MICROCHEMICAL JOURNAL, 160 (105753). [PMID:] [10.1016/j.microc.2020.105753] |
| 11. Guo-Cheng Liu, Yan Li, Ying Xiong, Xiang-Xiang Liu, Qiao-Min Li, Ju-Wen Zhang, Hong-Yan Lin, Xiao-Wu Li. (2018) Spacers-directed structural diversity of Co(II)/Zn(II) complexes based on S-/O-bridged dipyridylamides: electrochemical, fluorescent recognition behavior and photocatalytic properties. JOURNAL OF COORDINATION CHEMISTRY, [PMID:] [10.1080/00958972.2018.1438606] |