Determine the necessary mass, volume, or concentration for preparing a solution.
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Synonyms | 2,6-DIHYDROXYBENZOIC ACID | 303-07-1 | gamma-Resorcylic acid | 2-Carboxyresorcinol | 6-Hydroxysalicylic acid | 2,6-Resorcylic acid | Benzoic acid, 2,6-dihydroxy- | .gamma.-Resorcylic acid | 2,6-Dihydroxybenzoicacid | 2,6-dihydroxy benzoic acid | RSA5G6VRPV | MFCD00002462 | 2,6-d |
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Specifications & Purity | 10mM in DMSO |
Storage Temp | Protected from light,Store at -80°C |
Shipped In | Ice chest + Ice pads |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2,6-dihydroxybenzoic acid |
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INCHI | InChI=1S/C7H6O4/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,8-9H,(H,10,11) |
InChi Key | AKEUNCKRJATALU-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=C(C(=C1)O)C(=O)O)O |
Isomeric SMILES | C1=CC(=C(C(=C1)O)C(=O)O)O |
WGK Germany | 3 |
RTECS | DG8578000 |
Alternate CAS | 303-07-1 |
PubChem CID | 9338 |
NSC Number | 49172 |
MeSH Entry Terms | 2,6-dihydroxybenzoic acid;gamma-resorcylic acid |
Molecular Weight | 154.12 |
Beilstein | 2209755 |
Reaxy-Rn | 2209755 |
Enter Lot Number to search for COA:
Sensitivity | Light sensitive. |
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Melt Point(°C) | 160-165°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | DG8578000 |
Reaxy-Rn | 2209755 |
1. Xiu-Ni Hua, Xia Pan, Yang Zhu, Zhuoer Cai, Qi Song, Yaozhenhui Li, Wenbin Feng, Xin Chen, Hui Zhang, Baiwang Sun. (2022) Novel pharmaceutical salts of cephalexin with organic counterions: structural analysis and properties. RSC Advances, 12 (54): (34843-34850). [PMID:36540208] [10.1039/D2RA05565A] |
2. Yujiang Xie, Genpei Shi, Jie Sun, Si Li, Wei Gao, Yimin Hu, Chang Zu, Weiwei Tang, Junbo Gong. (2022) Computational Screening and Experimental Validation on Multicomponent Crystals of a New Class of Janus Kinase (JAK) Inhibitor Drug with Improved Solubility. Crystals, 12 (12): (1722). [PMID:] [10.3390/cryst12121722] |
3. Guojia Yu, Xinjian Chen, Lichao He, Xiangrong Li, Zhiyong Zhou, Zhongqi Ren. (2021) Study on the solubilization of telmisartan by forming cocrystals with aromatic carboxylic acids. CRYSTENGCOMM, 23 (27): (4871-4878). [PMID:] [10.1039/D1CE00551K] |
4. Deying Meng, Huangmei Zhou, Jianhua Xu, Sanjun Zhang. (2021) Studies on the interaction of salicylic acid and its monohydroxy substituted derivatives with bovine serum albumin. CHEMICAL PHYSICS, 546 (111182). [PMID:] [10.1016/j.chemphys.2021.111182] |
5. Ma Mingxuan, Du Yingxiang, Zhang Liu, Gan Jie, Yang Jiangxia. (2020) β-Cyclodextrin covalent organic framework–modified organic polymer monolith as a stationary phase for combined hydrophilic and hydrophobic aqueous capillary electrochromatographic separation of small molecules. MICROCHIMICA ACTA, 187 (7): (1-11). [PMID:32533434] [10.1007/s00604-020-04360-1] |
6. Mingfang Zhu, Hongqing Ye, Mushen Lai, Jianshan Ye, Rui Li, Wenhao Zhang, Huanru Liang, Rongkun Zhu, Huajun Fan, Shi Chen. (2019) The gold nanoparticle sensitized pRGO-MWCNTs grid modified carbon fiber microelectrode as an efficient sensor system for simultaneous detection of three dihydroxybenzoic acid isomers. ELECTROCHIMICA ACTA, 322 (134765). [PMID:] [10.1016/j.electacta.2019.134765] |
7. Qiqin Wang, Huihui Wu, Kun Peng, Hanying Jin, Huikai Shao, Yuqiang Wang, Jacques Crommen, Zhengjin Jiang. (2018) Hydrophilic polymeric monoliths containing choline phosphate for separation science applications. ANALYTICA CHIMICA ACTA, 999 (184). [PMID:29254571] [10.1016/j.aca.2017.11.032] |
8. Yuyan Wang, Yanxin Chen, Peipei Zhu, Ying Bao, Chuang Xie, Junbo Gong, Xiaobin Jiang, Baohong Hou, Wei Chen. (2017) Measurement and Correlation of the Solubility of 2,6-Dihydroxybenzoic Acid in Alcohols and Binary Solvents. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 62 (10): (3009–3014). [PMID:] [10.1021/acs.jced.6b00957] |
9. Guangxin Yuan, Yongbo Peng, Zhenghua Liu, Jieya Hong, Yao Xiao, Jialiang Guo, Norman W. Smith, Jacques Crommen, Zhengjin Jiang. (2013) A facile and efficient strategy to enhance hydrophilicity of zwitterionic sulfoalkylbetaine type monoliths. JOURNAL OF CHROMATOGRAPHY A, 1301 (88). [PMID:23796416] [10.1016/j.chroma.2013.05.063] |
10. Yuanqing Fu, Shan Hong, Duo Li, Songbai Liu. (2013) Novel Chemical Synthesis of Ginkgolic Acid (13:0) and Evaluation of Its Tyrosinase Inhibitory Activity. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 61 (22): (5347–5352). [PMID:23701207] [10.1021/jf4012642] |
1. Xiu-Ni Hua, Xia Pan, Yang Zhu, Zhuoer Cai, Qi Song, Yaozhenhui Li, Wenbin Feng, Xin Chen, Hui Zhang, Baiwang Sun. (2022) Novel pharmaceutical salts of cephalexin with organic counterions: structural analysis and properties. RSC Advances, 12 (54): (34843-34850). [PMID:36540208] [10.1039/D2RA05565A] |
2. Yujiang Xie, Genpei Shi, Jie Sun, Si Li, Wei Gao, Yimin Hu, Chang Zu, Weiwei Tang, Junbo Gong. (2022) Computational Screening and Experimental Validation on Multicomponent Crystals of a New Class of Janus Kinase (JAK) Inhibitor Drug with Improved Solubility. Crystals, 12 (12): (1722). [PMID:] [10.3390/cryst12121722] |
3. Guojia Yu, Xinjian Chen, Lichao He, Xiangrong Li, Zhiyong Zhou, Zhongqi Ren. (2021) Study on the solubilization of telmisartan by forming cocrystals with aromatic carboxylic acids. CRYSTENGCOMM, 23 (27): (4871-4878). [PMID:] [10.1039/D1CE00551K] |
4. Deying Meng, Huangmei Zhou, Jianhua Xu, Sanjun Zhang. (2021) Studies on the interaction of salicylic acid and its monohydroxy substituted derivatives with bovine serum albumin. CHEMICAL PHYSICS, 546 (111182). [PMID:] [10.1016/j.chemphys.2021.111182] |
5. Ma Mingxuan, Du Yingxiang, Zhang Liu, Gan Jie, Yang Jiangxia. (2020) β-Cyclodextrin covalent organic framework–modified organic polymer monolith as a stationary phase for combined hydrophilic and hydrophobic aqueous capillary electrochromatographic separation of small molecules. MICROCHIMICA ACTA, 187 (7): (1-11). [PMID:32533434] [10.1007/s00604-020-04360-1] |
6. Mingfang Zhu, Hongqing Ye, Mushen Lai, Jianshan Ye, Rui Li, Wenhao Zhang, Huanru Liang, Rongkun Zhu, Huajun Fan, Shi Chen. (2019) The gold nanoparticle sensitized pRGO-MWCNTs grid modified carbon fiber microelectrode as an efficient sensor system for simultaneous detection of three dihydroxybenzoic acid isomers. ELECTROCHIMICA ACTA, 322 (134765). [PMID:] [10.1016/j.electacta.2019.134765] |
7. Qiqin Wang, Huihui Wu, Kun Peng, Hanying Jin, Huikai Shao, Yuqiang Wang, Jacques Crommen, Zhengjin Jiang. (2018) Hydrophilic polymeric monoliths containing choline phosphate for separation science applications. ANALYTICA CHIMICA ACTA, 999 (184). [PMID:29254571] [10.1016/j.aca.2017.11.032] |
8. Yuyan Wang, Yanxin Chen, Peipei Zhu, Ying Bao, Chuang Xie, Junbo Gong, Xiaobin Jiang, Baohong Hou, Wei Chen. (2017) Measurement and Correlation of the Solubility of 2,6-Dihydroxybenzoic Acid in Alcohols and Binary Solvents. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 62 (10): (3009–3014). [PMID:] [10.1021/acs.jced.6b00957] |
9. Guangxin Yuan, Yongbo Peng, Zhenghua Liu, Jieya Hong, Yao Xiao, Jialiang Guo, Norman W. Smith, Jacques Crommen, Zhengjin Jiang. (2013) A facile and efficient strategy to enhance hydrophilicity of zwitterionic sulfoalkylbetaine type monoliths. JOURNAL OF CHROMATOGRAPHY A, 1301 (88). [PMID:23796416] [10.1016/j.chroma.2013.05.063] |
10. Yuanqing Fu, Shan Hong, Duo Li, Songbai Liu. (2013) Novel Chemical Synthesis of Ginkgolic Acid (13:0) and Evaluation of Its Tyrosinase Inhibitory Activity. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 61 (22): (5347–5352). [PMID:23701207] [10.1021/jf4012642] |