Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | 2,6-dimethyl pyridine | alpha,alpha'-Dimethylpyridine | BBL013176 | 2,6-Litidine-d6 | 2,6-Lutidine, analytical standard | AM10711 | 2.6-dimethylpyridine | DTXSID7051557 | AKOS005716680 | .alpha.,.alpha.'-Lutidine | AC-5116 | CHEBI:32548 | DTXCID1030109 | |
|---|---|
| Specifications & Purity | Distillation grade, ≥99% |
| Grade | Distillation grade |
| Product Description | 2,6-Lutidine, also known as 2,6-dimethylpyridine, is an organic compound that is commonly used as a reagent in various organic reactions, such as the synthesis of heterocycles, nitroalkenes, and alkyl halides. It can also be used as a catalyst in organic synthesis. Application 2,6-Lutidine can be used as: A base in the synthesis of an aldol adduct from malonic acid hemithioesters and aldehydes catalyzed by Cu(II) salt. An additive in reductive cyclization of epoxygeranyl acetate. A catalyst in combination with CuI for selective synthesis of N -sulfonyl-1,2,3.Flammable liquid-triazoles. |
Associated Targets(Human)
CHRNA3 Tclin Neuronal acetylcholine receptor subunit alpha-3 (0 Activities)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 2,6-dimethylpyridine |
|---|---|
| INCHI | InChI=1S/C7H9N/c1-6-4-3-5-7(2)8-6/h3-5H,1-2H3 |
| InChi Key | OISVCGZHLKNMSJ-UHFFFAOYSA-N |
| Canonical SMILES | CC1=NC(=CC=C1)C |
| Isomeric SMILES | CC1=NC(=CC=C1)C |
| WGK Germany | 3 |
| RTECS | OK9700000 |
| PubChem CID | 7937 |
| UN Number | 2734 |
| Packing Group | I |
| Molecular Weight | 107.15 |
| Beilstein | 105690 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Solubility | Soluble in ether, acetone, alcohol, water |
|---|---|
| Sensitivity | Air sensitive；Light sensitive |
| Refractive Index | 1.4966-1.4986 |
| Flash Point(°C) | 33℃ |
| Boil Point(°C) | 143-145°C |
| Melt Point(°C) | -6°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07, GHS02 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H226:Flammable liquid and vapor |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P271:Use only outdoors or in a well-ventilated area. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| RTECS | OK9700000 |
| Class | 8, 3 |
| Merck Index | 5616 |
Related Documents
Alternative Products
-
2,6-LutidineStarting at $14.90
-
2,6-LutidineStarting at $487.90
FAQs and Articles
FAQ
Indium (low valent)
Categories: Technical articles
Citations of This Product
| 1. Jiarong Qiu, Ben Zhou, Qiyue Yang, Yi Liu, Liangqing Zhang, Bingshu Wang, Shunming Song, Jingwen Zhang, Suchang Huang, Jianfeng Chen, Lu Lin, Xianhai Zeng. (2024) Efficient catalytic transfer hydrogenation of furfural and other biomass-derived compounds over sustainable magnetic catalyst. FUEL PROCESSING TECHNOLOGY, 254 (108010). [PMID:] [10.1016/j.fuproc.2023.108010] |
| 2. Bohong Yu, Yubo Liu, Yingxi Zhang, Linyi Xu, Kai Jin, Andi Sun, Xiuli Zhao, Yongjun Wang, Hongzhuo Liu. (2023) An SS31-rapamycin conjugate via RBC hitchhiking for reversing acute kidney injury. BIOMATERIALS, 303 (7): (122383). [PMID:37939640] [10.1016/j.biomaterials.2023.122383] |
| 3. Jun-Tao Shi, Xian-Hui Chen, Yuan-Yuan Peng, Gui-Ping Wang, Guang-Yan Du, Quan Li. (2023) Tunable Fluorescence and Morphology of Aggregates Built from a Mechanically Bonded Amphiphilic Bistable [2]Rotaxane. CHEMISTRY-A EUROPEAN JOURNAL, 29 (59): (e202302132). [PMID:37526053] [10.1002/chem.202302132] |
| 4. Yuan Li, Yuyang Wei, Wenbin Zhang. (2020) Oxidation behavior of N-hydroxyphthalimide (NHPI) and its electrocatalytic ability toward benzyl alcohol: Proton acceptor effect. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 870 (114251). [PMID:] [10.1016/j.jelechem.2020.114251] |
| 5. Chen Pei-Ling, Shi Qun-Ying, Chen Tian, Wang Ping, Liu Yun, Liu Li-Han. (2020) A dual-usage near-infrared (NIR) cell membrane targeting chimeric peptide for cancer cell membrane imaging and photothermal ablation. JOURNAL OF MATERIALS SCIENCE, 55 (18): (7843-7856). [PMID:] [10.1007/s10853-020-04546-1] |
| 6. Haifeng Wang, Zhenjiang Zhang, Puguang Ji, Xiaoyan Yu, Kimiyoshi Naito, Qingxin Zhang. (2018) Synthesis and properties of a novel high-temperature vinylpyridine-based phthalonitrile polymer. HIGH PERFORMANCE POLYMERS, [PMID:] [10.1177/0954008318801911] |
| 7. Hao Xu, Qinming Wu, Yueying Chu, Jingang Jiang, Ling Zhang, Shuxiang Pan, Changsheng Zhang, Longfeng Zhu, Feng Deng, Xiangju Meng, Stefan Maurer, Robert McGuire, Andrei-Nicolae Parvulescu, Ulrich Müller, Feng-Shou Xiao. (2018) Efficient synthesis of aluminosilicate RTH zeolite with good catalytic performances in NH3-SCR and MTO reactions. Journal of Materials Chemistry A, 6 (18): (8705-8711). [PMID:] [10.1039/C8TA01734D] |
| 8. Hong Cheng, Shi-Ying Li, Hao-Ran Zheng, Chu-Xin Li, Bo-Ru Xie, Ke-Wei Chen, Bin Li, Xian-Zheng Zhang. (2017) Multi-Förster Resonance Energy Transfer-Based Fluorescent Probe for Spatiotemporal Matrix Metalloproteinase-2 and Caspase-3 Imaging. ANALYTICAL CHEMISTRY, 89 (8): (4349–4354). [PMID:28365980] [10.1021/acs.analchem.7b00277] |
| 9. Houbo Zhou, Yi Chen, Christopher M. Plummer, Huahua Huang, Yongming Chen. (2017) Facile and efficient bromination of hydroxyl-containing polymers to synthesize well-defined brominated polymers. Polymer Chemistry, 8 (14): (2189-2196). [PMID:] [10.1039/C7PY00283A] |
| 10. Qiang Yu, Yanhong Liu, Diansheng Liu, Jianfeng Li. (2015) Geometric and electronic structures of five-coordinate manganese(II) “picket fence” porphyrin complexes. DALTON TRANSACTIONS, 44 (20): (9382-9390). [PMID:25913615] [10.1039/C5DT00685F] |
| 11. Jinshou Wang, Boan Shi, Zhen Shi, Yu Cao, Yingxuan Liu, Shenghui Zhang. (2013) Saponification of ethyl acetate in 2,6-lutidine + water near its critical point. PHYSICS AND CHEMISTRY OF LIQUIDS, [PMID:] [10.1080/00319104.2012.717890] |
References
| 1. Wensheng Yu,Yan Mei,Ying Kang,Zhengmao Hua,Zhendong Jin. (2004-09-10) Improved procedure for the oxidative cleavage of olefins by OsO4-NaIO4.. Organic letters, 6 ((19)): (3217-3219). [PMID:15355016] |
| 2. Ikuo Nakanishi,Tomonori Kawashima,Kei Ohkubo,Hideko Kanazawa,Keiko Inami,Masataka Mochizuki,Kiyoshi Fukuhara,Haruhiro Okuda,Toshihiko Ozawa,Shinobu Itoh,Shunichi Fukuzumi,Nobuo Ikota. (2005-02-11) Electron-transfer mechanism in radical-scavenging reactions by a vitamin E model in a protic medium.. Organic & biomolecular chemistry, 3 ((4)): (626-629). [PMID:15703798] |
| 3. Jun Gao,Maria Papadaki. (2005-10-26) Global kinetic model: a case study on the N-oxidation of alkylpyridines.. Journal of hazardous materials, 130 ((1-2)): (141-147). [PMID:16243432] |
| 4. Toshiaki Suzuki,Yoshitaka Hamashima,Mikiko Sodeoka. (2007-06-15) Asymmetric fluorination of alpha-aryl acetic acid derivatives with the catalytic system NiCl2-Binap/R3SiOTf/2,6-lutidine.. Angewandte Chemie (International ed. in English), 46 ((28)): (5435-5439). [PMID:17568468] |
| 5. D S Van Meter,O D Stuart,A B Carle,A M Stalcup. (2008-03-07) Characterization of a novel pyridinium bromide surface confined ionic liquid stationary phase for high-performance liquid chromatography under normal phase conditions via linear solvation energy relationships.. Journal of chromatography. A, 1191 ((1-2)): (67-71). [PMID:18321522] |
| 6. Qingnan Liu,Daniel K Havey,Ziman Li,Amy S Mullin. (2009-03-24) Effects of alkylation on deviations from Lennard-Jones collision rates for highly excited aromatic molecules: collisions of methylated pyridines with HOD.. The journal of physical chemistry. A, 113 ((16)): (4387-4396). [PMID:19301894] |
| 7. Cyrille Costentin,Viviane Hajj,Marc Robert,Jean-Michel Savéant,Cédric Tard. (2010-07-06) Effect of base pairing on the electrochemical oxidation of guanine.. Journal of the American Chemical Society, 132 ((29)): (10142-10147). [PMID:20597511] |
| 8. Dongling Wu,Dianzeng Jia,Lang Liu,Li Zhang,Jixi Guo. (2010-10-07) Reactivity of 2,6-lutidine/BR₃ and pyridine/BR₃ Lewis pairs (R = F, Me, C₆F₅): a density functional study.. The journal of physical chemistry. A, 114 ((43)): (11738-11745). [PMID:20923207] |
| 9. Kathryn A White,Andrew B Schofield,Philip Wormald,Joseph W Tavacoli,Bernard P Binks,Paul S Clegg. (2011-04-22) Inversion of particle-stabilized emulsions of partially miscible liquids by mild drying of modified silica particles.. Journal of colloid and interface science, 359 ((1)): (126-135). [PMID:21507417] |
| 10. Elena Arceo,Igor D Jurberg,Ana Alvarez-Fernández,Paolo Melchiorre. (2013-08-24) Photochemical activity of a key donor-acceptor complex can drive stereoselective catalytic α-alkylation of aldehydes.. Nature chemistry, 5 ((9)): (750-756). [PMID:23965676] |
| 11. Laura Robaldo,Alfredo Berzal-Herranz,Javier M Montserrat,Adolfo M Iribarren. (2014-08-01) Activity of core-modified 10-23 DNAzymes against HCV.. ChemMedChem, 9 ((9)): (2172-2177). [PMID:25079672] |
| 12. Daniel Zewge,Francis Gosselin,Denise M Kenski,Jenny Li,Vasant Jadhav,Yu Yuan,Sandhya S Nerurkar,David M Tellers,W Michael Flanagan,Ian W Davies. (2014-11-15) High-throughput chemical modification of oligonucleotides for systematic structure-activity relationship evaluation.. Bioconjugate chemistry, 25 ((12)): (2222-2232). [PMID:25398098] |
| 13. Meital Bloch,Lauren Jablonowski,Eylon Yavin,Dorit Moradov,Irena Djavsarov,Abraham Nyska,Margaret Wheatley,Abraham Rubinstein. (2014-12-02) Multi-modal detection of colon malignancy by NIR-tagged recognition polymers and ultrasound contrast agents.. International journal of pharmaceutics, 478 ((2)): (504-516). [PMID:25437110] |
| 14. Monika Witala,Roberto Nervo,Oleg Konovalov,Kim Nygård. (2015-06-25) Microscopic segregation of hydrophilic ions in critical binary aqueous solvents.. Soft matter, 11 ((29)): (5883-5888). [PMID:26107528] |
| 15. James R Frost,Colin M Pearson,Thomas N Snaddon,Richard A Booth,Richard M Turner,Johan Gold,David M Shaw,Matthew J Gaunt,Steven V Ley. (2015-08-01) Callipeltosides A, B and C: Total Syntheses and Structural Confirmation.. Chemistry (Weinheim an der Bergstrasse, Germany), 21 ((38)): (13261-13277). [PMID:26230615] |
| 16. Masazumi Tamura,Ryota Kishi,Yoshinao Nakagawa,Keiichi Tomishige. (2015-10-06) Self-assembled hybrid metal oxide base catalysts prepared by simply mixing with organic modifiers.. Nature communications, 6 (8580-8580). [PMID:26436638] |
| 17. Bojana Ginovska,Tom Autrey,Kshitij Parab,Mark E Bowden,Robert G Potter,Donald M Camaioni. (2015-10-24) Heterolysis of H2 Across a Classical Lewis Pair, 2,6-Lutidine⋅BCl3 : Synthesis, Characterization, and Mechanism.. Chemistry (Weinheim an der Bergstrasse, Germany), 21 ((44)): (15713-15719). [PMID:26493883] |
| 18. Matthew T Holden,Matthew C D Carter,Cheng-Hsien Wu,Jamison Wolfer,Eric Codner,Michael R Sussman,David M Lynn,Lloyd M Smith. (2015-10-24) Photolithographic Synthesis of High-Density DNA and RNA Arrays on Flexible, Transparent, and Easily Subdivided Plastic Substrates.. Analytical chemistry, 87 ((22)): (11420-11428). [PMID:26494264] |
| 19. Jiarong Qiu, Ben Zhou, Qiyue Yang, Yi Liu, Liangqing Zhang, Bingshu Wang, Shunming Song, Jingwen Zhang, Suchang Huang, Jianfeng Chen, Lu Lin, Xianhai Zeng. (2024) Efficient catalytic transfer hydrogenation of furfural and other biomass-derived compounds over sustainable magnetic catalyst. FUEL PROCESSING TECHNOLOGY, 254 (108010). [PMID:] [10.1016/j.fuproc.2023.108010] |
| 20. Bohong Yu, Yubo Liu, Yingxi Zhang, Linyi Xu, Kai Jin, Andi Sun, Xiuli Zhao, Yongjun Wang, Hongzhuo Liu. (2023) An SS31-rapamycin conjugate via RBC hitchhiking for reversing acute kidney injury. BIOMATERIALS, 303 (7): (122383). [PMID:37939640] [10.1016/j.biomaterials.2023.122383] |
| 21. Jun-Tao Shi, Xian-Hui Chen, Yuan-Yuan Peng, Gui-Ping Wang, Guang-Yan Du, Quan Li. (2023) Tunable Fluorescence and Morphology of Aggregates Built from a Mechanically Bonded Amphiphilic Bistable [2]Rotaxane. CHEMISTRY-A EUROPEAN JOURNAL, 29 (59): (e202302132). [PMID:37526053] [10.1002/chem.202302132] |
| 22. Yuan Li, Yuyang Wei, Wenbin Zhang. (2020) Oxidation behavior of N-hydroxyphthalimide (NHPI) and its electrocatalytic ability toward benzyl alcohol: Proton acceptor effect. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 870 (114251). [PMID:] [10.1016/j.jelechem.2020.114251] |
| 23. Chen Pei-Ling, Shi Qun-Ying, Chen Tian, Wang Ping, Liu Yun, Liu Li-Han. (2020) A dual-usage near-infrared (NIR) cell membrane targeting chimeric peptide for cancer cell membrane imaging and photothermal ablation. JOURNAL OF MATERIALS SCIENCE, 55 (18): (7843-7856). [PMID:] [10.1007/s10853-020-04546-1] |
| 24. Haifeng Wang, Zhenjiang Zhang, Puguang Ji, Xiaoyan Yu, Kimiyoshi Naito, Qingxin Zhang. (2018) Synthesis and properties of a novel high-temperature vinylpyridine-based phthalonitrile polymer. HIGH PERFORMANCE POLYMERS, [PMID:] [10.1177/0954008318801911] |
| 25. Hao Xu, Qinming Wu, Yueying Chu, Jingang Jiang, Ling Zhang, Shuxiang Pan, Changsheng Zhang, Longfeng Zhu, Feng Deng, Xiangju Meng, Stefan Maurer, Robert McGuire, Andrei-Nicolae Parvulescu, Ulrich Müller, Feng-Shou Xiao. (2018) Efficient synthesis of aluminosilicate RTH zeolite with good catalytic performances in NH3-SCR and MTO reactions. Journal of Materials Chemistry A, 6 (18): (8705-8711). [PMID:] [10.1039/C8TA01734D] |
| 26. Hong Cheng, Shi-Ying Li, Hao-Ran Zheng, Chu-Xin Li, Bo-Ru Xie, Ke-Wei Chen, Bin Li, Xian-Zheng Zhang. (2017) Multi-Förster Resonance Energy Transfer-Based Fluorescent Probe for Spatiotemporal Matrix Metalloproteinase-2 and Caspase-3 Imaging. ANALYTICAL CHEMISTRY, 89 (8): (4349–4354). [PMID:28365980] [10.1021/acs.analchem.7b00277] |
| 27. Houbo Zhou, Yi Chen, Christopher M. Plummer, Huahua Huang, Yongming Chen. (2017) Facile and efficient bromination of hydroxyl-containing polymers to synthesize well-defined brominated polymers. Polymer Chemistry, 8 (14): (2189-2196). [PMID:] [10.1039/C7PY00283A] |
| 28. Qiang Yu, Yanhong Liu, Diansheng Liu, Jianfeng Li. (2015) Geometric and electronic structures of five-coordinate manganese(II) “picket fence” porphyrin complexes. DALTON TRANSACTIONS, 44 (20): (9382-9390). [PMID:25913615] [10.1039/C5DT00685F] |
| 29. Jinshou Wang, Boan Shi, Zhen Shi, Yu Cao, Yingxuan Liu, Shenghui Zhang. (2013) Saponification of ethyl acetate in 2,6-lutidine + water near its critical point. PHYSICS AND CHEMISTRY OF LIQUIDS, [PMID:] [10.1080/00319104.2012.717890] |