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2-(6-phenyl-1,3-benzothiazole-2-carbonyl)-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole , CAS No.P608687, Inhibitor of lipase G; endothelial type

Item Number
P608687
Grouped product items
SKUSizeAvailabilityPrice Qty
P608687-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,000.90
P608687-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
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lipase G，endothelial type Inhibitor (2)

Basic Description

Specifications & PurityMoligand™
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of lipase G; endothelial type

AI Insight

Associated Targets(Human)

LIPC Tchem Hepatic triacylglycerol lipase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
LIPG Tchem Endothelial lipase (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
LIPC Tchem Hepatic lipase (436 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

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Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-(6-phenyl-1,3-benzothiazole-2-carbonyl)-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
INCHI InChI=1S/C17H13N5O4S2/c18-28(24,25)19-9-14-21-22-16(26-14)15(23)17-20-12-7-6-11(8-13(12)27-17)10-4-2-1-3-5-10/h1-8,19H,9H2,(H2,18,24,25)
InChi Key LXSODRTWQNWTOG-UHFFFAOYSA-N
Canonical SMILES O=C(c1nc2c(s1)cc(cc2)c1ccccc1)c1nnc(o1)CNS(=O)(=O)N
Isomeric SMILES C1=CC=C(C=C1)C2=CC3=C(C=C2)N=C(S3)C(=O)C4=NN=C(O4)CNS(=O)(=O)N
PubChem CID 90057968

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Related Documents

 SDS

 Specification Sheet

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References

1. Tora G, Kim SH, Pi Z, Johnson JA, Jiang J, Phillips M, Lloyd J, Abell LM, Lu H, Locke G et al..  (2020)  Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo..  J Med Chem,  63  (4): (1660-1670).  [PMID:31990537] [10.1021/acs.jmedchem.9b01831]

Solution Calculators

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