2',7'-Dichlorofluorescein - indicator,≥90.0%, high purity , CAS No.76-54-0

Item Number
D113554
Grouped product items
SKUSizeAvailabilityPrice Qty
D113554-1g
1g
In stock
$21.90
D113554-5g
5g
In stock
$98.90
D113554-25g
25g
In stock
$134.90

Intracellular fluorescent label

Basic Description

SynonymsDichloro(R)fluorescein | DTXSID8058798 | HY-W040143A | 2',7'-DICHLOROFLUORESCEIN [MI] | FLUORESCEIN-27 | UNII-56NQM5UZT1 | Fluorescein 27 | Spiro[isobenzofuran-1(3H),9'-[9h]xanthen]-3-one,2',7'-dichloro-3',6'-dihydroxy- | CS-W020883 | 2',7'-Dichlorofluore
Specifications & Purityindicator, ≥90%
Biochemical and Physiological MechanismsIntracellular fluorescent label. Zinpyr-1, DCFA, DFCA DA and DCFDA N-succinimidyl ester precursor. Marker for cellular oxidative stress.
Shipped InNormal
Gradeindicator
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

for Fluorescent indicator

Associated Targets(Human)

UGT1A9 Tbio UDP-glucuronosyltransferase 1-9 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488183646
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488183646
IUPAC Name 2',7'-dichloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
INCHI InChI=1S/C20H10Cl2O5/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,23-24H
InChi Key VFNKZQNIXUFLBC-UHFFFAOYSA-N
Canonical SMILES C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C=C4OC5=CC(=C(C=C35)Cl)O)O)Cl
Isomeric SMILES C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C=C4OC5=CC(=C(C=C35)Cl)O)O)Cl
PubChem CID 64944
Molecular Weight 401.2
Beilstein 58009

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot NumberCertificate TypeDateItem
L2425010Certificate of AnalysisDec 28, 2024 D113554
L2418555Certificate of AnalysisDec 28, 2024 D113554
L2418554Certificate of AnalysisDec 28, 2024 D113554
C1720078Certificate of AnalysisNov 04, 2024 D113554
J2429120Certificate of AnalysisNov 01, 2024 D113554
E1605120Certificate of AnalysisJan 05, 2024 D113554
E2309759Certificate of AnalysisMay 15, 2023 D113554
E2309754Certificate of AnalysisMay 15, 2023 D113554
E2309747Certificate of AnalysisMay 15, 2023 D113554
E2309745Certificate of AnalysisMay 15, 2023 D113554
E2309726Certificate of AnalysisMay 15, 2023 D113554
K2214079Certificate of AnalysisNov 21, 2022 D113554
I2219422Certificate of AnalysisSep 24, 2022 D113554
C2225037Certificate of AnalysisApr 28, 2022 D113554
G2222629Certificate of AnalysisJun 02, 2021 D113554
G2222630Certificate of AnalysisJun 02, 2021 D113554
E2128106Certificate of AnalysisJun 02, 2021 D113554

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Chemical and Physical Properties

SolubilitySoluble in Solution of sodium hydroxide in water; Slightly soluble in Ethanol
Flash Point(°C)12°C
Melt Point(°C)280°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Related Documents

Citations of This Product

1. Miao Qiao, Xin Hua, Yongjun Yuan, Xi Cao.  (2023)  Enrichment of EPA and DHA by enzymatic ethanolysis: Effects of lipases from Thermomyces lanuginosus, Rhizomucor miehei, Rhizopus oryzae and Candida antarctica.  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY,      [PMID:] [10.1002/aocs.12800]
2. Xiangyu Meng, Yao Li, Yiqing Liu, Runyu Zhou, Yongsheng Fu, Junmin Chen.  (2023)  Degradation of organic pollutants through activating bisulfite with lanthanum ferrite-loaded biomass carbon.  RSC Advances,  13  (35): (24819-24829).  [PMID:37608974] [10.1039/D3RA04271E]
3. Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan.  (2024)  Highly bright stable organic radicals encapsulated by amphiphilic polypeptide for efficient near-infrared phototheranostics.  TALANTA,  266  (124948).  [PMID:37459788] [10.1016/j.talanta.2023.124948]
4. Ping Qi, Liangying Jia, Mengjiao Yi, Enzhi Zhao, Yihan Liu, Aixin Song, Jingcheng Hao.  (2022)  Chemiluminescent gels of G-quadruplexes in deep eutectic solvents.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  655  (130319).  [PMID:] [10.1016/j.colsurfa.2022.130319]
5. Bo Huang, Xiangmei Liu, Zhaoyang Li, Yufeng Zheng, Kelvin Wai Kwok Yeung, Zhenduo Cui, Yanqin Liang, Shengli Zhu, Shuilin Wu.  (2021)  Rapid bacteria capturing and killing by AgNPs/N-CD@ZnO hybrids strengthened photo-responsive xerogel for rapid healing of bacteria-infected wounds.  CHEMICAL ENGINEERING JOURNAL,  414  (128805).  [PMID:] [10.1016/j.cej.2021.128805]
6. Long Deng, Qian Zou, Biao Liu, Wenhui Ye, Chengfei Zhuo, Li Chen, Ze-Yuan Deng, Ya-Wei Fan, Jing Li.  (2018)  Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China.  Food & Function,  (8): (4234-4245).  [PMID:29999510] [10.1039/C8FO00787J]

References

1. Miao Qiao, Xin Hua, Yongjun Yuan, Xi Cao.  (2023)  Enrichment of EPA and DHA by enzymatic ethanolysis: Effects of lipases from Thermomyces lanuginosus, Rhizomucor miehei, Rhizopus oryzae and Candida antarctica.  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY,      [PMID:] [10.1002/aocs.12800]
2. Xiangyu Meng, Yao Li, Yiqing Liu, Runyu Zhou, Yongsheng Fu, Junmin Chen.  (2023)  Degradation of organic pollutants through activating bisulfite with lanthanum ferrite-loaded biomass carbon.  RSC Advances,  13  (35): (24819-24829).  [PMID:37608974] [10.1039/D3RA04271E]
3. Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan.  (2024)  Highly bright stable organic radicals encapsulated by amphiphilic polypeptide for efficient near-infrared phototheranostics.  TALANTA,  266  (124948).  [PMID:37459788] [10.1016/j.talanta.2023.124948]
4. Ping Qi, Liangying Jia, Mengjiao Yi, Enzhi Zhao, Yihan Liu, Aixin Song, Jingcheng Hao.  (2022)  Chemiluminescent gels of G-quadruplexes in deep eutectic solvents.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  655  (130319).  [PMID:] [10.1016/j.colsurfa.2022.130319]
5. Bo Huang, Xiangmei Liu, Zhaoyang Li, Yufeng Zheng, Kelvin Wai Kwok Yeung, Zhenduo Cui, Yanqin Liang, Shengli Zhu, Shuilin Wu.  (2021)  Rapid bacteria capturing and killing by AgNPs/N-CD@ZnO hybrids strengthened photo-responsive xerogel for rapid healing of bacteria-infected wounds.  CHEMICAL ENGINEERING JOURNAL,  414  (128805).  [PMID:] [10.1016/j.cej.2021.128805]
6. Long Deng, Qian Zou, Biao Liu, Wenhui Ye, Chengfei Zhuo, Li Chen, Ze-Yuan Deng, Ya-Wei Fan, Jing Li.  (2018)  Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China.  Food & Function,  (8): (4234-4245).  [PMID:29999510] [10.1039/C8FO00787J]

Solution Calculators