The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied.
Product Application
2-Adamantylamine hydrochloride was used to prepare 2-adamantylamide of 2'-(carboxymethoxime)-olivomycin I. The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
1.Yahui Zhang, Haifeng Yao, Yongping Dong. (2024) Electrochemiluminescence of an iridium complex doped with SiO2 nanoparticles to detect 2-adamantanamine based on the host–guest interaction of cucurbit[7]uril. ANALYST, 149 (4):(1160-1168). [PMID:38167663][10.1039/D3AN02021E]
References
1.Yasuhiko Higashi,Shota Nakamura,Hiroki Matsumura,Youichi Fujii. (2005-09-15) Simultaneous liquid chromatographic assay of amantadine and its four related compounds in phosphate-buffered saline using 4-fluoro-7-nitro-2,1,3-benzoxadiazole as a fluorescent derivatization reagent.. Biomedical chromatography : BMC, 20 ((5)):(423-428). [PMID:16161183]
2.Alina A Okhina,Artem D Rogachev,Olga I Yarovaya,Mikhail V Khvostov,Tatyana G Tolstikova,Andrey G Pokrovsky,Veniamin A Khazanov,Nariman F Salakhutdinov. (2019-12-23) Development and validation of an LC-MS/MS method for the quantitative analysis of the anti-influenza agent camphecene in rat plasma and its application to study the blood-to-plasma distribution of the agent.. Journal of pharmaceutical and biomedical analysis, 180 (113039-113039). [PMID:31865208]
3.C Clark,M M Woodson,H T Nagasawa. (1991-01-01) Inhibition of lymphocyte proliferation by amantadine and its isomer, 2-aminoadamantane; impact on Lyt-2+ T cells while sparing L3T4+ T cells.. Immunopharmacology, 21 ((1)):(41-50). [PMID:1860784]
4.Iu V Vakhitova,R S Iamidanov,V A Vakhitov,S B Seredenin. (2005-04-29) [DNA macroarray analysis of gene expression changes in rat brain after single administration of 2-aminoadamantane compound].. Molekuliarnaia biologiia, 39 ((2)):(276-285). [PMID:15856951]
5.Anna N Tevyashova,Eugenia N Olsufyeva,Eugenia N Zbarsky,Jan Balzarini,Alexander A Shtil,Lyubov G Dezhenkova,Vladimir M Bukhman,Victor B Zbarsky,Maria N Preobrazhenskaya. (2009-01-10) Modification of the antibiotic olivomycin I at the 2'-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity.. The Journal of antibiotics, 62 ((1)):(37-41). [PMID:19132061]
6.Yahui Zhang, Haifeng Yao, Yongping Dong. (2024) Electrochemiluminescence of an iridium complex doped with SiO2 nanoparticles to detect 2-adamantanamine based on the host–guest interaction of cucurbit[7]uril. ANALYST, 149 (4):(1160-1168). [PMID:38167663][10.1039/D3AN02021E]
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G2404150