2-amino-2-Norbornanecarboxylic Acid - 97%, high purity , CAS No.20448-79-7

Item Number
B287272
Grouped product items
SKUSizeAvailabilityPrice Qty
B287272-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$18.90
B287272-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$39.90
B287272-50mg
50mg
In stock
$64.90
B287272-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$107.90

LAT1 inhibitor

Basic Description

Synonyms20448-79-7 | 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid | 2-Amino-2-norbornanecarboxylic acid | 2-Aminonorbornane-2-carboxylic acid | BCH | LAT1-IN-1 | CHEMBL2074957 | Bicyclo[2.2.1]heptane-2-carboxylic acid, 2-amino- | b-BCH | Bicyclo(2.2.1)heptane-2-carboxylic acid,
Specifications & PurityMoligand™, ≥97%
Biochemical and Physiological MechanismsInhibitor ofL-type amino acid transporter LAT1. Suppresses growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines.2-Amino-2-desmethylboronic acid (BCH) is a Na(+)-independent system-specific substrate, and other syst
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™

Associated Targets(Human)

MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC7A5 Tchem L-type amino acid transporter 1 (388 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC43A1 Tbio L-type amino acid transporter 3 (7 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A15 Tchem Sodium-dependent neutral amino acid transporter B(0)AT2 (42 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Slc16a10 Monocarboxylate transporter 10 (73 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 2-aminobicyclo[2.2.1]heptane-2-carboxylic acid
INCHI InChI=1S/C8H13NO2/c9-8(7(10)11)4-5-1-2-6(8)3-5/h5-6H,1-4,9H2,(H,10,11)
InChi Key MPUVBVXDFRDIPT-UHFFFAOYSA-N
Canonical SMILES C1CC2CC1CC2(C(=O)O)N
Isomeric SMILES C1CC2CC1CC2(C(=O)O)N
PubChem CID 115288
Molecular Weight 155.2

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
C2426042Certificate of AnalysisJun 14, 2023 B287272
G2320404Certificate of AnalysisJun 14, 2023 B287272
G2320406Certificate of AnalysisJun 14, 2023 B287272
J2325025Certificate of AnalysisJun 14, 2023 B287272

Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 15.52, Max Conc. mM: 100
SensitivityMoisture sensitive

Related Documents

Solution Calculators