Basic Description

Synonyms	2-Amino-3-pyridinecarboxylic acid \| F2191-0192 \| STK701078 \| 2-Amino-3-carboxypyridine \| NSC 3049 \| FT-0611255 \| Iminodibenyl \| Propyl phenyl ketone \| RP-3854 \| Tserenox \| 2-Amino-3-pyridinecarboyxlic acid \| EINECS 226-296-3 \| AC-2436 \| BBL001472 \| EN300-
Specifications & Purity	≥98%
Shipped In	Normal

Associated Targets(Human)

NAPRT Tchem Nicotinate phosphoribosyltransferase (2 Activities)

Discover Target: NAPRT

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DAO Tchem D-amino-acid oxidase (802 Activities)

Discover Target: DAO

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DDO Tchem D-aspartate oxidase (120 Activities)

Discover Target: DDO

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Gabrp GABA-A receptor; anion channel (5731 Activities)

Discover Target: Gabrp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488184744
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488184744
IUPAC Name	2-aminopyridine-3-carboxylic acid
INCHI	InChI=1S/C6H6N2O2/c7-5-4(6(9)10)2-1-3-8-5/h1-3H,(H2,7,8)(H,9,10)
InChi Key	KPIVDNYJNOPGBE-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=C(N=C1)N)C(=O)O
Isomeric SMILES	C1=CC(=C(N=C1)N)C(=O)O
WGK Germany	3
PubChem CID	72930
Molecular Weight	138.12
Beilstein	119031
Reaxy-Rn	119031

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot Number	Certificate Type	Date	Item
C2404083	Certificate of Analysis	Mar 30, 2024	A107211
C2404084	Certificate of Analysis	Mar 30, 2024	A107211
C2404085	Certificate of Analysis	Mar 30, 2024	A107211
B2324380	Certificate of Analysis	Mar 06, 2023	A107211
B2324396	Certificate of Analysis	Mar 02, 2023	A107211
I2209099	Certificate of Analysis	Jul 13, 2022	A107211
I2209101	Certificate of Analysis	Jul 13, 2022	A107211
I2209102	Certificate of Analysis	Jul 13, 2022	A107211

Chemical and Physical Properties

Melt Point(°C)	297°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	119031

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Peng Qiu, Zhaorui Song. (2023) Determination of Nicotinic Acid in Food and Pharmaceuticals by a Simple and Rapid Fluorescence Polarization Immunoassay (FPIA). ANALYTICAL LETTERS, [PMID:] [10.1080/00032719.2023.2173220]
2. Si-Fu Tang, Xiao-Bo Pan, Xiao-Xia Lv, Xue-Bo Zhao. (2013) Investigation on three new metal carboxydiphosphonates: Syntheses, structures, magnetic and luminescent properties. JOURNAL OF SOLID STATE CHEMISTRY, 197 (139). [PMID:] [10.1016/j.jssc.2012.08.052]

References

1. Y Ohba,M Sakata,K Zaitsu. (2000-08-26) Chemiluminescence derivatization of methylglyoxal using 2-aminonicotinic acid.. Chemical & pharmaceutical bulletin, 48 ((8)): (1236-1238). [PMID:10959598]
2. Mehmet Karabacak,Etem Kose,Ahmet Atac. (2012-03-01) Molecular structure (monomeric and dimeric structure) and HOMO-LUMO analysis of 2-aminonicotinic acid: a comparison of calculated spectroscopic properties with FT-IR and UV-vis.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 91 (83-96). [PMID:22366618]
3. Ghasem Marandi. (2018-04-18) Synthesis of 3-(Cyclohexylamino)-2-arylimidazo[1,2-a]pyridine-8- carboxylic Acids Via an Efficient Three-component Condensation Reaction between Cyclohexylisocyanide and 2-Aminopyridine-3-carboxylic Acid in the Presence of Aromatic Aldehyde.. Combinatorial chemistry & high throughput screening, 21 ((4)): (298-301). [PMID:29663877]
4. A J Dobson,R E Gerkin. (1997-11-18) 2-Aminonicotinic acid.. Acta crystallographica. Section C, Crystal structure communications, 53 ( Pt 10) (1427-1429). [PMID:9362553]
5. Ronald Bartzatt. (2007-10-30) Alkylation activity and molecular properties of two antineoplastic agents that utilise indometacin and a conjugate of aspirin with 2-aminonicotinic acid to transport nitrogen mustard groups.. Drugs in R&D, 8 ((6)): (363-372). [PMID:17963427]
6. Gian Paolo Vallerini,Laura Amori,Claudia Beato,Margarita Tararina,Xiao-Dan Wang,Robert Schwarcz,Gabriele Costantino. (2013-11-28) 2-Aminonicotinic acid 1-oxides are chemically stable inhibitors of quinolinic acid synthesis in the mammalian brain: a step toward new antiexcitotoxic agents.. Journal of medicinal chemistry, 56 ((23)): (9482-9495). [PMID:24274468]
7. Tycho Marinus,Adam B Fessler,Craig A Ogle,Danny Incarnato. (2021-01-06) A novel SHAPE reagent enables the analysis of RNA structure in living cells with unprecedented accuracy.. Nucleic acids research, 49 ((6)): (e34-e34). [PMID:33398343]
8. Peng Qiu, Zhaorui Song. (2023) Determination of Nicotinic Acid in Food and Pharmaceuticals by a Simple and Rapid Fluorescence Polarization Immunoassay (FPIA). ANALYTICAL LETTERS, [PMID:] [10.1080/00032719.2023.2173220]
9. Si-Fu Tang, Xiao-Bo Pan, Xiao-Xia Lv, Xue-Bo Zhao. (2013) Investigation on three new metal carboxydiphosphonates: Syntheses, structures, magnetic and luminescent properties. JOURNAL OF SOLID STATE CHEMISTRY, 197 (139). [PMID:] [10.1016/j.jssc.2012.08.052]

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SKU	Size	Availability	Price
A107211-5g	5g	Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks.	$30.90
A107211-25g	25g	In stock	$136.90
A107211-100g	100g	In stock	$492.90

2-Aminonicotinic acid - 98%, high purity , CAS No.5345-47-1