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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A109732-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $15.90 | |
A109732-10g | 10g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $23.90 | |
A109732-25g | 25g | In stock | $44.90 | |
A109732-100g | 100g | In stock | $160.90 | |
A109732-250g | 250g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $361.90 | |
A109732-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $650.90 |
Synonyms | Q27117919 | 2-Aminopyrimidine, 97% | AI3-24128 | 2(1H)-Pyrimidinimine, (E)- (9CI) | 2-aminopirimidina | 2-Pyrimidinamine | A927973 | SULFADIAZINE IMPURITY A [EP IMPURITY] | EINECS 203-648-4 | EN300-17309 | MB00175 | Pyrimidinamine | Sulfadiazine impurity |
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Specifications & Purity | ≥98% |
Storage Temp | Protected from light |
Shipped In | Normal |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488180637 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488180637 |
IUPAC Name | pyrimidin-2-amine |
INCHI | InChI=1S/C4H5N3/c5-4-6-2-1-3-7-4/h1-3H,(H2,5,6,7) |
InChi Key | LJXQPZWIHJMPQQ-UHFFFAOYSA-N |
Canonical SMILES | C1=CN=C(N=C1)N |
Isomeric SMILES | C1=CN=C(N=C1)N |
WGK Germany | 3 |
RTECS | UV6326000 |
PubChem CID | 7978 |
Molecular Weight | 95.1 |
Beilstein | 107014 |
Reaxy-Rn | 107014 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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H2402100 | Certificate of Analysis | Apr 30, 2024 | A109732 |
H2402101 | Certificate of Analysis | Apr 30, 2024 | A109732 |
G2426560 | Certificate of Analysis | Apr 30, 2024 | A109732 |
B2224045 | Certificate of Analysis | Jan 19, 2022 | A109732 |
B2224047 | Certificate of Analysis | Jan 19, 2022 | A109732 |
I2318152 | Certificate of Analysis | Jan 19, 2022 | A109732 |
B2325327 | Certificate of Analysis | Jun 01, 2021 | A109732 |
K2426216 | Certificate of Analysis | Jun 01, 2021 | A109732 |
Solubility | Soluble in water; Soluble in Methanol |
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Flash Point(°F) | 103 °C |
Flash Point(°C) | 103°C |
Boil Point(°C) | 158°C |
Melt Point(°C) | 127°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H303:May be harmful if swallowed |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P312:Call a POISON CENTER or doctor/... if you feel unwell. P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. |
WGK Germany | 3 |
RTECS | UV6326000 |
Reaxy-Rn | 107014 |
1. Pei Chen, Hui Zhu, Tianhao Na, Yong Yi, Jian Zhou, Tao Duan, Jiehong Lei. (2023) Functionalized collagen fiber with specific recognition sites for highly efficient iodine capture: theoretical calculations and experimental verification. CHEMICAL ENGINEERING JOURNAL, 476 (15): (146660). [PMID:12432077] [10.1016/j.cej.2023.146660] |
2. Yongshuang Huang, Jie Li, Meizhou Qi, Guifu Si, Chen Tan. (2023) In Situ Modification to Reinforce Isoprene Rubber by Sacrificial Bonds. ACS Applied Polymer Materials, 5 (6): (4080–4087). [PMID:] [10.1021/acsapm.3c00304] |
3. Yulin Sun, Saiyi Zhong, Qinqin Luo, Biao Yu, Jiangli Song, Dexin Tan. (2022) A vanillin-derived flame retardant based on 2-aminopyrimidine for enhanced flame retardancy and mechanical properties of epoxy resin. POLYMERS FOR ADVANCED TECHNOLOGIES, 34 (1): (166-180). [PMID:] [10.1002/pat.5875] |
1. Teruyoshi Kitamura,Atushi Hikita,Hironori Ishikawa,Akira Fujimoto. (2005-06-28) Photoinduced amino-imino tautomerization reaction in 2-aminopyrimidine and its methyl derivatives with acetic acid.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 62 ((4-5)): (1157-1164). [PMID:15978861] |
2. Ye-Xiang Xie,Shao-Feng Pi,Jian Wang,Du-Lin Yin,Jin-Heng Li. (2006-10-10) 2-aminopyrimidine-4,6-diol as an efficient ligand for solvent-free copper-catalyzed N-arylations of imidazoles with aryl and heteroaryl halides.. The Journal of organic chemistry, 71 ((21)): (8324-8327). [PMID:17025338] |
3. S A Abdel-Latif,H B Hassib,Y M Issa. (2006-11-07) Studies on some salicylaldehyde Schiff base derivatives and their complexes with Cr(III), Mn(II), Fe(III), Ni(II) and Cu(II).. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 67 ((3-4)): (950-957). [PMID:17084104] |
4. Adel M Awadallah,Jalal A Zahra. (2008-02-09) Reaction of nitrilimines with 2-substituted aza-heterocycles. Synthesis of pyrrolo[1,2-a]pyridine and pyrimido[2,1-d]1,2,3,5- tetrazine.. Molecules (Basel, Switzerland), 13 ((1)): (170-176). [PMID:18259139] |
5. Robert J Altenbach,Ronald M Adair,Brian M Bettencourt,Lawrence A Black,Shannon R Fix-Stenzel,Sujatha M Gopalakrishnan,Gin C Hsieh,Huaqing Liu,Kennan C Marsh,Michael J McPherson,Ivan Milicic,Thomas R Miller,Timothy A Vortherms,Usha Warrior,Jill M Wetter,Neil Wishart,David G Witte,Prisca Honore,Timothy A Esbenshade,Arthur A Hancock,Jorge D Brioni,Marlon D Cowart. (2008-09-25) Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligands.. Journal of medicinal chemistry, 51 ((20)): (6571-6580). [PMID:18811133] |
6. Graham Smith,Urs D Wermuth,Jonathan M White. (2009-03-07) Zero-, one- and two-dimensional hydrogen-bonded structures in the 1:1 proton-transfer compounds of 4,5-dichlorophthalic acid with the monocyclic heteroaromatic Lewis bases 2-aminopyrimidine, nicotinamide and isonicotinamide.. Acta crystallographica. Section C, Crystal structure communications, 65 ((Pt 3)): (o103-o107). [PMID:19265221] |
7. Manuel Tzouros,Axel Pähler. (2009-03-26) A targeted proteomics approach to the identification of peptides modified by reactive metabolites.. Chemical research in toxicology, 22 ((5)): (853-862). [PMID:19317514] |
8. Paul S Humphries,Jennifer A Lafontaine,Charles S Agree,David Alexander,Ping Chen,Quyen-Quyen T Do,Lilian Y Li,Elizabeth A Lunney,Ranjan J Rajapakse,Karen Siegel,Sergei L Timofeevski,Tianlun Wang,David M Wilhite. (2009-03-31) Synthesis and SAR of 4-substituted-2-aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors.. Bioorganic & medicinal chemistry letters, 19 ((8)): (2099-2102). [PMID:19327989] |
9. Nicholas R Perl,Nathan D Ide,Sudeep Prajapati,Hahdi H Perfect,Sergio G Durón,David Y Gin. (2010-01-26) Annulation of thioimidates and vinyl carbodiimides to prepare 2-aminopyrimidines, competent nucleophiles for intramolecular alkyne hydroamination. Synthesis of (-)-crambidine.. Journal of the American Chemical Society, 132 ((6)): (1802-1803). [PMID:20095555] |
10. Jinho Lee,Kyoung-Hee Kim,Shinwu Jeong. (2011-06-21) Discovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors.. Bioorganic & medicinal chemistry letters, 21 ((14)): (4203-4205). [PMID:21684737] |
11. Erick A Lindsey,Roberta J Worthington,Cristina Alcaraz,Christian Melander. (2012-02-04) 2-Aminopyrimidine as a novel scaffold for biofilm modulation.. Organic & biomolecular chemistry, 10 ((13)): (2552-2561). [PMID:22301774] |
12. Rajani Giridhar,Riyaj S Tamboli,R Ramajayam,Dhaval G Prajapati,M R Yadav. (2012-02-14) Assessment of antiplatelet activity of 2-aminopyrimidines.. European journal of medicinal chemistry, 50 (428-432). [PMID:22326145] |
13. Kamaljit Singh,Hardeep Kaur,Kelly Chibale,Jan Balzarini,Susan Little,Prasad V Bharatam. (2012-03-31) 2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.. European journal of medicinal chemistry, 52 (82-97). [PMID:22459876] |
14. N Prabavathi,A Nilufer,V Krishnakumar,L Akilandeswari. (2012-06-12) Spectroscopic, electronic structure and natural bond analysis of 2-aminopyrimidine and 4-aminopyrazolo[3,4-d]pyrimidine: a comparative study.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 96 (226-241). [PMID:22683558] |
15. Maya Tutughamiarso,Guido Wagner,Ernst Egert. (2012-07-20) Cocrystals of 5-fluorocytosine. I. Coformers with fixed hydrogen-bonding sites.. Acta crystallographica. Section B, Structural science, 68 ((Pt 4)): (431-443). [PMID:22810913] |
16. Andrej Pevec,. (2015-06-19) Synthesis and Structural Study of Some Pyrimidinium Hexafluoridosilicates.. Acta chimica Slovenica, 62 ((2)): ( 297-303 ). [PMID:26085410] |
17. Teodor Silviu Balaban,Richard Goddard,Myriam Linke-Schaetzel,Jean-Marie Lehn. (2003-04-03) 2-Aminopyrimidine directed self-assembly of zinc porphyrins containing bulky 3,5-di-tert-butylphenyl groups.. Journal of the American Chemical Society, 125 ((14)): (4233-4239). [PMID:12670245] |
18. A Aĭtmambetov,Z Menlimuratova. (2003-04-24) [Interaction of synthetic analogues of natural chalcones and flavones with guanidine].. Bioorganicheskaia khimiia, 29 ((2)): (198-199). [PMID:12708320] |
19. Rogier A Smits,Rob Leurs,Iwan J P de Esch. (2009-05-30) Major advances in the development of histamine H4 receptor ligands.. Drug discovery today, 14 ((15-16)): (745-753). [PMID:19477292] |
20. Miguel Angel Vilchis-Reyes,Alejandro Zentella,Miguel Angel Martínez-Urbina,Angel Guzmán,Omar Vargas,María Teresa Ramírez Apan,José Luis Ventura Gallegos,Eduardo Díaz. (2009-11-03) Synthesis and cytotoxic activity of 2-methylimidazo[1,2-a]pyridine- and quinoline-substituted 2-aminopyrimidine derivatives.. European journal of medicinal chemistry, 45 ((1)): (379-386). [PMID:19879023] |
21. Markus K Dahlgren,Christopher T Oberg,Erika A Wallin,Pär G Janson,Mikael Elofsson. (2010-07-27) Synthesis of 2-(2-aminopyrimidine)-2,2-difluoroethanols as potential bioisosters of salicylidene acylhydrazides.. Molecules (Basel, Switzerland), 15 ((6)): (4423-4438). [PMID:20657451] |
22. Xusheng Wang,Hongdeng Qiu,Xia Liu,Shengxiang Jiang. (2011-06-11) [Separation of bases, phenols and pharmaceuticals on ionic liquid-modified silica stationary phase with pure water as mobile phase].. Se pu = Chinese journal of chromatography, 29 ((3)): (269-272). [PMID:21657060] |
23. Nimisha Singh,Sarvesh Kumar Pandey,Namrata Anand,Richa Dwivedi,Shyam Singh,Sudhir Kumar Sinha,Vinita Chaturvedi,Natasa Jaiswal,Arvind Kumar Srivastava,Priyanka Shah,M Imran Siddiqui,Rama Pati Tripathi. (2011-07-09) Synthesis, molecular modeling and bio-evaluation of cycloalkyl fused 2-aminopyrimidines as antitubercular and antidiabetic agents.. Bioorganic & medicinal chemistry letters, 21 ((15)): (4404-4408). [PMID:21737274] |
24. Namrata Anand,Priyanka Singh,Anindra Sharma,Sameer Tiwari,Vandana Singh,Diwakar K Singh,Kishore K Srivastava,B N Singh,Rama Pati Tripathi. (2012-08-03) Synthesis and evaluation of small libraries of triazolylmethoxy chalcones, flavanones and 2-aminopyrimidines as inhibitors of mycobacterial FAS-II and PknG.. Bioorganic & medicinal chemistry, 20 ((17)): (5150-5163). [PMID:22854194] |
25. Sabine Schultes,Harald Engelhardt,Luc Roumen,Obbe P Zuiderveld,Eric E J Haaksma,Iwan J P de Esch,Rob Leurs,Chris de Graaf. (2012-11-20) Combining quantum mechanical ligand conformation analysis and protein modeling to elucidate GPCR-ligand binding modes.. ChemMedChem, 8 ((1)): (49-53). [PMID:23161844] |
26. Manishkumar D Joshi,Tianhao Li,Qiqing Zhong,Jared L Anderson. (2013-08-21) Using glucaminium-based ionic liquids for improving the separation of 2-aminopyrimidine-5-ylboronic acid and its pinacol ester by high performance liquid chromatography.. Journal of chromatography. A, 1308 (161-165). [PMID:23958694] |
27. Pei Chen, Hui Zhu, Tianhao Na, Yong Yi, Jian Zhou, Tao Duan, Jiehong Lei. (2023) Functionalized collagen fiber with specific recognition sites for highly efficient iodine capture: theoretical calculations and experimental verification. CHEMICAL ENGINEERING JOURNAL, 476 (15): (146660). [PMID:12432077] [10.1016/j.cej.2023.146660] |
28. Yongshuang Huang, Jie Li, Meizhou Qi, Guifu Si, Chen Tan. (2023) In Situ Modification to Reinforce Isoprene Rubber by Sacrificial Bonds. ACS Applied Polymer Materials, 5 (6): (4080–4087). [PMID:] [10.1021/acsapm.3c00304] |
29. Yulin Sun, Saiyi Zhong, Qinqin Luo, Biao Yu, Jiangli Song, Dexin Tan. (2022) A vanillin-derived flame retardant based on 2-aminopyrimidine for enhanced flame retardancy and mechanical properties of epoxy resin. POLYMERS FOR ADVANCED TECHNOLOGIES, 34 (1): (166-180). [PMID:] [10.1002/pat.5875] |