Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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B191082-50ml | 50ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $219.90 |
Synonyms | Alotano | CAS-151-67-7 | CCG-213438 | DTXCID605371 | Fluothane, Halothane, USP | HMS2094K17 | Halotano | Narkotan | NCGC00090868-02 | ETHANE, 2-BROMO-2-CHLORO-1,1,1-TRIFLUORO-,(+/-)- | Halothane [Anaesthetics, volatile] | HY-B1010 | Freon 123B1 | Narcotan |
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Specifications & Purity | Moligand™, ≥99% |
Biochemical and Physiological Mechanisms | 2-Bromo-2-chloro-1,1,1-trifluoroethane is an inhalation anesthetic. In an effect believed to be independent of anesthesia, halothane inhibits the synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step. |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ACTIVATOR, CHANNEL BLOCKER, GATING INHIBITOR, INHIBITOR, POSITIVE MODULATOR |
Mechanism of action | Potassium channel subfamily K member 18 opener |
Product Description | Application 2-Bromo-2-chloro-1,1,1-trifluoroethane, or halothane, has been used in a study that combined molecular simulations with free energy simulations to study solvation of halothane in polarizable water and methanol. Halothane has also been used in a study to investigate the interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor. |
ALogP | 2.3 |
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Enter Lot Number to search for COA:
Solubility | Soluble in water (8 mg/ml) |
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Sensitivity | Light sensitive |
Refractive Index | n20/D 1.369 |
Boil Point(°C) | 50.2 °C |
Pictogram(s) | GHS08, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H335:May cause respiratory irritation H341:Suspected of causing genetic defects H318:Causes serious eye damage H360:May damage fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
Class | 9 |
Starting at $169.90
1. Meadows HJ, Randall AD. (2001) Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel.. Neuropharmacology, 40 (4): (551-9). [PMID:11249964] [10.1021/op500134e] |
2. Talley EM, Bayliss DA. (2002) Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: volatile anesthetics and neurotransmitters share a molecular site of action.. J Biol Chem, 277 (20): (17733-42). [PMID:11886861] [10.1021/op500134e] |