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2-Bromo-2-chloro-1,1,1-trifluoroethane - 10mM in DMSO, high purity , CAS No.151-67-7(DMSO)

  • Moligand™
  • 10mM in DMSO
Item Number
B580274
Grouped product items
SKUSizeAvailabilityPrice Qty
B580274-1ml
1ml
Available within 8-12 weeks(?)
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$169.90
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Potassium Channel

Basic Description

Synonymshalothane|151-67-7|2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE|Fluothane|Narcotane|Rhodialothan|Anestan|Bromochlorotrifluoroethane|Phthorothanum|Ftuorotan|Halothan|Narcotan|Fluorotane|Fluktan|Ftorotan|Narkotan|Halotano|Freon 123B1|Halotan|Halsan|Halan|Chalotha
Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms2-Bromo-2-chloro-1,1,1-trifluoroethane is an inhalation anesthetic. In an effect believed to be independent of anesthesia, halothane inhibits the synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Product Description

Application

2-Bromo-2-chloro-1,1,1-trifluoroethane, or halothane, has been used in a study that combined molecular simulations with free energy simulations to study solvation of halothane in polarizable water and methanol. Halothane has also been used in a study to investigate the interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor.

Associated Targets

CYP2E1 Tchem Cytochrome P450 2E1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CACNA1C Tclin Voltage-dependent L-type calcium channel subunit alpha-1C 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALB Tchem Serum albumin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOB Tclin Amine oxidase [flavin-containing] B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNK3 Tclin Potassium channel subfamily K member 3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNK5 Tchem Potassium channel subfamily K member 5 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNK9 Tclin Potassium channel subfamily K member 9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNB1 Tclin Potassium voltage-gated channel subfamily B member 1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-bromo-2-chloro-1,1,1-trifluoroethane
INCHI InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H
InChi Key BCQZXOMGPXTTIC-UHFFFAOYSA-N
Canonical SMILES C(C(F)(F)F)(Cl)Br
Isomeric SMILES C(C(F)(F)F)(Cl)Br
PubChem CID 3562
Molecular Weight 197.38

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water (8 mg/ml)
SensitivityLight sensitive

Related Documents

Solution Calculators