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2-Chloro-N6-cyclopentyladenosine - 98%, high purity , CAS No.37739-05-2, Agonist of A 1 receptor;Agonist of A 2A receptor;Agonist of A 2B receptor;Agonist of A 3 receptor

≥98%

CAS#: 37739-05-2
Formula: C₁₅H₂₀ClN₅O₄
Molecular Weight: 369.8
PubChem CID: 123807

Item Number

C170001

Grouped product items
SKU	Size	Availability	Price
C170001-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$151.90
C170001-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$339.90
C170001-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,223.90

Highly potent, selective A 1 agonist

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A1 receptor Agonist A2A receptor Agonist A2B receptor Agonist A3 receptor Agonist

Basic Description

Synonyms	CCPA\|2-Chloro-N6-cyclopentyladenosine\|37739-05-2\|2-CHLORO-N-CYCLOPENTYLADENOSINE\|2-chloro-N(6)cyclopentyladenosine\|Adenosine, 2-chloro-N-cyclopentyl-\|[3H]CCPA\|JX2F2W6WSP\|(2R,3R,4S,5R)-2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,
Specifications & Purity	98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Action Type	AGONIST
Mechanism of action	Agonist of A 1 receptor;Agonist of A 2A receptor;Agonist of A 2B receptor;Agonist of A 3 receptor

Associated Targets

ADORA2A Tclin Adenosine receptor A2a 3 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA2B Tclin Adenosine receptor A2b 1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA1 Tclin Adenosine receptor A1 15 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 12 Activities

Discover Target: ADORA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(2R,3R,4S,5R)-2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
INCHI	InChI=1S/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1
InChi Key	XSMYYYQVWPZWIZ-IDTAVKCVSA-N
Canonical SMILES	C1CCC(C1)NC2=C3C(=NC(=N2)Cl)N(C=N3)C4C(C(C(O4)CO)O)O
Isomeric SMILES	C1CCC(C1)NC2=C3C(=NC(=N2)Cl)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O
Alternate CAS	37739-05-2
PubChem CID	123807
MeSH Entry Terms	2-CCPA;2-chloro-N(6)cyclopentyladenosine;CCPA-2;CCPA-2-chloro-N(6)-cyclopentyladenosine;CCPA-2-Cl-N-CPA
Molecular Weight	369.8

PubChem CID

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ChEMBL Ligand

CAS Registry No.

GPCRdb Ligand

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6 results found

Lot Number	Certificate Type	Date	Item
H2105143	Certificate of Analysis	May 10, 2024	C170001
H2105144	Certificate of Analysis	May 10, 2024	C170001
H2105145	Certificate of Analysis	May 10, 2024	C170001
G2219306	Certificate of Analysis	Jun 06, 2022	C170001
G2219308	Certificate of Analysis	Jun 06, 2022	C170001
G2219313	Certificate of Analysis	Jun 06, 2022	C170001

References

1. Fujimoto K et al.. (2019) Adenosine Attenuates Aortic Smooth Muscle Cell Calcification through A3 Adenosine Receptor.. Tohoku J Exp Med, 249 (4): (275-283). [PMID:31875581]
2. Yi X et al.. (2018) Adenosine receptors enhance the ATP-induced odontoblastic differentiation of human dental pulp cells.. Biochem Biophys Res Commun, 497 (3): (850-856). [PMID:29454963]

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