2'-Deoxyadenosine 5'-triphosphate [dATP] trisodium salt trihydrate - ≥98%, high purity , CAS No.1927-31-7, Agonist of P2Y 11 receptor

Item Number
D276527
Grouped product items
SKUSizeAvailabilityPrice Qty
D276527-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$118.90

Nucleoside triphosphate.

View related series
P2Y11 receptor Agonist

Basic Description

SynonymsAdenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy- | UNII-K8KCC8SH6N | 4-26-00-03593 (Beilstein Handbook Reference) | EINECS 217-662-3 | AS-69027 | Epitope ID:149167 | Q201090 | D-erythro-pentitol, 1-C-(7-amino-1H-pyrazolo(4,3-d)pyrimidin-3-yl)-1,4-anhy
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsNucleoside triphosphate. Substrate for a variety of polymerases including DNA polymerase(s) and reverse transcriptase(s). Used in DNA synthesis reactions such as PCR, DNA sequencing and molecular cloning techniques.
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of P2Y 11 receptor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(Human)

P2RY11 Tchem P2Y purinoceptor 11 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
POLA1 Tclin DNA polymerase alpha subunit (225 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TK1 Tchem Thymidine kinase, cytosolic (627 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P2RY11 Tchem Purinergic receptor P2Y11 (134 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TK2 Tchem Thymidine kinase, mitochondrial (96 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

pol Human immunodeficiency virus type 1 reverse transcriptase (18245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mat1a S-adenosylmethionine synthetase alpha and beta forms (31 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mat2a S-adenosylmethionine synthetase gamma form (83 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P2RY1 P2Y purinoceptor 1 (470 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name [[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
INCHI InChI=1S/C10H16N5O12P3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1
InChi Key SUYVUBYJARFZHO-RRKCRQDMSA-N
Canonical SMILES C1C(C(OC1N2C=NC3=C(N=CN=C32)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
Isomeric SMILES C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
Molecular Weight 491.18

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water to 75 mM

Safety and Hazards(GHS)

Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

Related Documents

Citations of This Product

1. Liangliang Wang, Xiufeng Wu, Guanyu Chen, Yawen Chen, Lilan Xu, Jianmin Wang, Jinghua Chen.  (2024)  Dual amplified electrochemical sensing coupling of ternary hybridization-based exosomal microRNA recognition and perchlorate-assisted electrocatalytic cycle.  BIOSENSORS & BIOELECTRONICS,  243  (20): (115783).  [PMID:23084991] [10.1016/j.bios.2023.115783]
2. Liu Xufei, Qiu Shengqiang, Mei Peng, Zhang Qing, Yang Yingkui.  (2021)  Chain structure-dependent electrochemical performance of polyimide cathode materials for lithium-ion batteries.  JOURNAL OF MATERIALS SCIENCE,  56  (5): (3900-3910).  [PMID:] [10.1007/s10853-020-05510-9]
3. Liang-Liang Wang, Wen-Qian Chen, Yu-Ru Wang, Lu-Peng Zeng, Ting-Ting Chen, Guan-Yu Chen, Jing-Hua Chen.  (2020)  Numerous long single-stranded DNAs produced by dual amplification reactions for electrochemical detection of exosomal microRNAs.  BIOSENSORS & BIOELECTRONICS,  169  (112555).  [PMID:32927348] [10.1016/j.bios.2020.112555]
4. Zheng Dan, Guo Peng, Xiong Juan, Wang Shengfu.  (2016)  Streptavidin Modified ZnO Film Bulk Acoustic Resonator for Detection of Tumor Marker Mucin 1.  Nanoscale Research Letters,  11  (1): (1-8).  [PMID:27624339] [10.1186/s11671-016-1612-5]
5. Wei Wen, Jing-Yi Huang, Ting Bao, Jun Zhou, Hong-Xing Xia, Xiu-Hua Zhang, Sheng-Fu Wang, Yuan-Di Zhao.  (2016)  Increased electrocatalyzed performance through hairpin oligonucleotide aptamer-functionalized gold nanorods labels and graphene-streptavidin nanomatrix: Highly selective and sensitive electrochemical biosensor of carcinoembryonic antigen.  BIOSENSORS & BIOELECTRONICS,  83  (142).  [PMID:27111123] [10.1016/j.bios.2016.04.039]
6. Chunyan Qin, Wei Wen, Xiuhua Zhang, Haoshuang Gu, Shengfu Wang.  (2015)  Visual detection of thrombin using a strip biosensor through aptamer-cleavage reaction with enzyme catalytic amplification.  ANALYST,  140  (22): (7710-7717).  [PMID:26451394] [10.1039/C5AN01712B]

References

1. Liangliang Wang, Xiufeng Wu, Guanyu Chen, Yawen Chen, Lilan Xu, Jianmin Wang, Jinghua Chen.  (2024)  Dual amplified electrochemical sensing coupling of ternary hybridization-based exosomal microRNA recognition and perchlorate-assisted electrocatalytic cycle.  BIOSENSORS & BIOELECTRONICS,  243  (20): (115783).  [PMID:23084991] [10.1016/j.bios.2023.115783]
2. Liu Xufei, Qiu Shengqiang, Mei Peng, Zhang Qing, Yang Yingkui.  (2021)  Chain structure-dependent electrochemical performance of polyimide cathode materials for lithium-ion batteries.  JOURNAL OF MATERIALS SCIENCE,  56  (5): (3900-3910).  [PMID:] [10.1007/s10853-020-05510-9]
3. Liang-Liang Wang, Wen-Qian Chen, Yu-Ru Wang, Lu-Peng Zeng, Ting-Ting Chen, Guan-Yu Chen, Jing-Hua Chen.  (2020)  Numerous long single-stranded DNAs produced by dual amplification reactions for electrochemical detection of exosomal microRNAs.  BIOSENSORS & BIOELECTRONICS,  169  (112555).  [PMID:32927348] [10.1016/j.bios.2020.112555]
4. Zheng Dan, Guo Peng, Xiong Juan, Wang Shengfu.  (2016)  Streptavidin Modified ZnO Film Bulk Acoustic Resonator for Detection of Tumor Marker Mucin 1.  Nanoscale Research Letters,  11  (1): (1-8).  [PMID:27624339] [10.1186/s11671-016-1612-5]
5. Wei Wen, Jing-Yi Huang, Ting Bao, Jun Zhou, Hong-Xing Xia, Xiu-Hua Zhang, Sheng-Fu Wang, Yuan-Di Zhao.  (2016)  Increased electrocatalyzed performance through hairpin oligonucleotide aptamer-functionalized gold nanorods labels and graphene-streptavidin nanomatrix: Highly selective and sensitive electrochemical biosensor of carcinoembryonic antigen.  BIOSENSORS & BIOELECTRONICS,  83  (142).  [PMID:27111123] [10.1016/j.bios.2016.04.039]
6. Chunyan Qin, Wei Wen, Xiuhua Zhang, Haoshuang Gu, Shengfu Wang.  (2015)  Visual detection of thrombin using a strip biosensor through aptamer-cleavage reaction with enzyme catalytic amplification.  ANALYST,  140  (22): (7710-7717).  [PMID:26451394] [10.1039/C5AN01712B]

Solution Calculators