Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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D155667-5g | 5g | In stock | $26.90 | |
D155667-25g | 25g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $117.90 |
Synonyms | adenine-9 2-deoxy-b-D-erythro-Pentofuranoside | 9-(2-deoxy-b-D-ribofuranosyl)-9H-Purin-6-amine | NSC-141848 | P582C98ULC | beta-D-Ribofuranose, 1-(6-amino-9H-purin-9-yl)-1,2-dideoxy- | CS-W021069 | 5-(6-AMINO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3 |
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Specifications & Purity | Moligand™, ≥98%(HPLC)(T) |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Product Description | 2′-Deoxyadenosine, also called DNA nucleoside A, is a nucleoside adenosine derivative. 2′-Deoxyadenosine pairs with deoxythymidine (T) in double-stranded DNA. In absence of adenosine deaminase (ADA) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease (ADA-SCID). |
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IUPAC Name | (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol |
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INCHI | InChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1 |
InChi Key | OLXZPDWKRNYJJZ-RRKCRQDMSA-N |
Canonical SMILES | C1C(C(OC1N2C=NC3=C(N=CN=C32)N)CO)O |
Isomeric SMILES | C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)O |
RTECS | AU7358600 |
PubChem CID | 13730 |
Molecular Weight | 251.25 |
Reaxy-Rn | 91015 |
CAS Registry No. | 958-09-8 |
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Wikipedia | Deoxyadenosine |
ChEBI | CHEBI:17256 |
PubChem CID | 13730 |
ChEMBL Ligand | CHEMBL449329 |
RCSB PDB Ligand | 3D1 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
F2418377 | Certificate of Analysis | Jun 12, 2024 | D155667 |
F2418378 | Certificate of Analysis | Jun 12, 2024 | D155667 |
F2418376 | Certificate of Analysis | Jun 12, 2024 | D155667 |
F2418379 | Certificate of Analysis | Jun 12, 2024 | D155667 |
B2207276 | Certificate of Analysis | Jan 07, 2022 | D155667 |
Sensitivity | Air Sensitive,Heat Sensitive |
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Specific Rotation[α] | -27° (C=0.5,H2O) |
Melt Point(°C) | 191 °C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
RTECS | AU7358600 |
Reaxy-Rn | 91015 |
1. Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan. (2024) Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers. SEPARATION AND PURIFICATION TECHNOLOGY, 330 (125346). [PMID:15220430] [10.1016/j.seppur.2023.125346] |
2. Ziyi Wang, Li Xu, Ting Zou, Furong Tang, Juan Zhang. (2024) Fabrication of boronic acid-functionalized covalent organic framework for the selective adsorption of cis-diol-containing compounds. APPLIED SURFACE SCIENCE, 644 (13): (158698). [PMID:28500754] [10.1016/j.apsusc.2023.158698] |
3. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang. (2023) A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr.. JOURNAL OF SEPARATION SCIENCE, 46 (21): (2300090). [PMID:37688342] [10.1002/jssc.202300090] |
4. Ziyi Wang, Ting Zou, Shitao Feng, Fengshou Wu, Juan Zhang. (2023) Boronic acid-functionalized magnetic porphyrin-based covalent organic framework for selective enrichment of cis-diol-containing nucleosides. ANALYTICA CHIMICA ACTA, 1278 (341691). [PMID:37709444] [10.1016/j.aca.2023.341691] |
5. Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan. (2023) Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 312 (123384). [PMID:] [10.1016/j.seppur.2023.123384] |
6. Pan Wang, Mengdei Zhou, Zhuangxin Wei, Lu Liu, Tao Cheng, Xiaohua Tian, Jianming Pan. (2023) Preparation of bowl-shaped polydopamine surface imprinted polymer composite adsorbent for specific separation of 2′-deoxyadenosine. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 60 (69). [PMID:] [10.1016/j.cjche.2023.01.009] |
7. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan. (2022) Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 302 (122048). [PMID:] [10.1016/j.seppur.2022.122048] |
8. Jia Ding, Fei Liu, Chunling Qi, Yunlei Zhou, Huanshun Yin, Shiyun Ai. (2021) Enhanced photoactivity of perovskite Bi4NbO8Cl/PTC-NH2 heterojunction and its application for photoelectrochemical sensing of DNA hydroxymethylation. SENSORS AND ACTUATORS B-CHEMICAL, 344 (130211). [PMID:] [10.1016/j.snb.2021.130211] |
9. Zhonghua Dong, Yueyue Sun, Guangwei Wei, Siying Li, Zhongxi Zhao. (2019) A Nucleoside/Nucleobase-Rich Extract from Cordyceps Sinensis Inhibits the Epithelial–Mesenchymal Transition and Protects against Renal Fibrosis in Diabetic Nephropathy. MOLECULES, 24 (22): (4119). [PMID:31739543] [10.3390/molecules24224119] |
10. Yuan Yuan, Min Jiang, Hongyang Zhang, Ju Liu, Min Zhang, Ping Hu. (2019) Simultaneous quantification of urinary purines and creatinine by ultra high performance liquid chromatography with ultraviolet spectroscopy and quadrupole time-of-flight mass spectrometry: Method development, validation, and application to gout study. JOURNAL OF SEPARATION SCIENCE, 42 (15): (2523-2533). [PMID:31144454] [10.1002/jssc.201900170] |
11. Deng Ya’nan, Gao Qin, Ma Juan, Wang Chaozhan, Wei Yinmao. (2018) Preparation of a boronate affinity material with ultrahigh binding capacity for cis-diols by grafting polymer brush from polydopamine-coated magnetized graphene oxide. MICROCHIMICA ACTA, 185 (3): (1-8). [PMID:29594797] [10.1007/s00604-018-2732-7] |
12. Yuanyuan Xu, Yue Yang, Aifang Xue, Hao Chen, Shengqing Li. (2018) In situ precipitation of hydrous titanium dioxide for dispersive micro solid-phase extraction of nucleosides and their separation. NEW JOURNAL OF CHEMISTRY, 42 (7): (4909-4914). [PMID:] [10.1039/C7NJ04590E] |
13. Yanan Pan, Xiumei Guo, Shanshan Li, Xiaoyan Liu, Haixia Zhang. (2018) A boronate-decorated porous carbon material derived from a zinc-based metal–organic framework for enrichment of cis-diol-containing nucleosides. NEW JOURNAL OF CHEMISTRY, 42 (3): (2288-2294). [PMID:] [10.1039/C7NJ04575A] |
14. Shuxia Wang, Huihui Li, Xiujuan Guan, Ting Cheng, Haixia Zhang. (2017) Silica – Boronate affinity material for quick enrichment of intracellular nucleosides. TALANTA, 166 (148). [PMID:28213215] [10.1016/j.talanta.2017.01.048] |
15. Huihui Li, Ting Cheng, Shuxia Wang, Xinyue Zhu, Haixia Zhang. (2016) High-efficiency extraction of nucleosides based on the combination of self-assembly ionic liquid layer and boronic acid-functionalized attapulgite. TALANTA, 153 (71). [PMID:27130092] [10.1016/j.talanta.2016.02.004] |
16. Chaozhan Wang, Huanhuan Xu, Yinmao Wei. (2016) The preparation of high-capacity boronate affinity adsorbents by surface initiated reversible addition fragmentation chain transfer polymerization for the enrichment of ribonucleosides in serum. ANALYTICA CHIMICA ACTA, 902 (115). [PMID:26703260] [10.1016/j.aca.2015.11.013] |
17. Li-li Zhang, Yong-liang Bai, Shu-lan Shu, Da-wei Qian, Zhen Ou-yang, Li Liu, Jin-ao Duan. (2014) Simultaneous quantitation of nucleosides, nucleobases, amino acids, and alkaloids in mulberry leaf by ultra high performance liquid chromatography with triple quadrupole tandem mass spectrometry. JOURNAL OF SEPARATION SCIENCE, 37 (11): (1265-1275). [PMID:24616434] [10.1002/jssc.201301267] |
18. Sheng Guo, Jin-ao Duan, Dawei Qian, Hanqing Wang, Yuping Tang, Yefei Qian, Dawei Wu, Shulan Su, Erxin Shang. (2013) Hydrophilic interaction ultra-high performance liquid chromatography coupled with triple quadrupole mass spectrometry for determination of nucleotides, nucleosides and nucleobases in Ziziphus plants. JOURNAL OF CHROMATOGRAPHY A, 1301 (147). [PMID:23800804] [10.1016/j.chroma.2013.05.074] |
19. Hengye Li,Xuemeng Zhang,Lin Zhang,Xiaojin Wang,Fenying Kong,Dahe Fan,Lei Li,Wei Wang. (2016-10-30) Preparation of a boronate affinity silica stationary phase with enhanced binding properties towards cis-diol compounds.. Journal of chromatography. A, 1473 (90-98). [PMID:27776772] |
1. Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan. (2024) Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers. SEPARATION AND PURIFICATION TECHNOLOGY, 330 (125346). [PMID:15220430] [10.1016/j.seppur.2023.125346] |
2. Ziyi Wang, Li Xu, Ting Zou, Furong Tang, Juan Zhang. (2024) Fabrication of boronic acid-functionalized covalent organic framework for the selective adsorption of cis-diol-containing compounds. APPLIED SURFACE SCIENCE, 644 (13): (158698). [PMID:28500754] [10.1016/j.apsusc.2023.158698] |
3. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang. (2023) A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr.. JOURNAL OF SEPARATION SCIENCE, 46 (21): (2300090). [PMID:37688342] [10.1002/jssc.202300090] |
4. Ziyi Wang, Ting Zou, Shitao Feng, Fengshou Wu, Juan Zhang. (2023) Boronic acid-functionalized magnetic porphyrin-based covalent organic framework for selective enrichment of cis-diol-containing nucleosides. ANALYTICA CHIMICA ACTA, 1278 (341691). [PMID:37709444] [10.1016/j.aca.2023.341691] |
5. Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan. (2023) Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 312 (123384). [PMID:] [10.1016/j.seppur.2023.123384] |
6. Pan Wang, Mengdei Zhou, Zhuangxin Wei, Lu Liu, Tao Cheng, Xiaohua Tian, Jianming Pan. (2023) Preparation of bowl-shaped polydopamine surface imprinted polymer composite adsorbent for specific separation of 2′-deoxyadenosine. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 60 (69). [PMID:] [10.1016/j.cjche.2023.01.009] |
7. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan. (2022) Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 302 (122048). [PMID:] [10.1016/j.seppur.2022.122048] |
8. Jia Ding, Fei Liu, Chunling Qi, Yunlei Zhou, Huanshun Yin, Shiyun Ai. (2021) Enhanced photoactivity of perovskite Bi4NbO8Cl/PTC-NH2 heterojunction and its application for photoelectrochemical sensing of DNA hydroxymethylation. SENSORS AND ACTUATORS B-CHEMICAL, 344 (130211). [PMID:] [10.1016/j.snb.2021.130211] |
9. Zhonghua Dong, Yueyue Sun, Guangwei Wei, Siying Li, Zhongxi Zhao. (2019) A Nucleoside/Nucleobase-Rich Extract from Cordyceps Sinensis Inhibits the Epithelial–Mesenchymal Transition and Protects against Renal Fibrosis in Diabetic Nephropathy. MOLECULES, 24 (22): (4119). [PMID:31739543] [10.3390/molecules24224119] |
10. Yuan Yuan, Min Jiang, Hongyang Zhang, Ju Liu, Min Zhang, Ping Hu. (2019) Simultaneous quantification of urinary purines and creatinine by ultra high performance liquid chromatography with ultraviolet spectroscopy and quadrupole time-of-flight mass spectrometry: Method development, validation, and application to gout study. JOURNAL OF SEPARATION SCIENCE, 42 (15): (2523-2533). [PMID:31144454] [10.1002/jssc.201900170] |
11. Deng Ya’nan, Gao Qin, Ma Juan, Wang Chaozhan, Wei Yinmao. (2018) Preparation of a boronate affinity material with ultrahigh binding capacity for cis-diols by grafting polymer brush from polydopamine-coated magnetized graphene oxide. MICROCHIMICA ACTA, 185 (3): (1-8). [PMID:29594797] [10.1007/s00604-018-2732-7] |
12. Yuanyuan Xu, Yue Yang, Aifang Xue, Hao Chen, Shengqing Li. (2018) In situ precipitation of hydrous titanium dioxide for dispersive micro solid-phase extraction of nucleosides and their separation. NEW JOURNAL OF CHEMISTRY, 42 (7): (4909-4914). [PMID:] [10.1039/C7NJ04590E] |
13. Yanan Pan, Xiumei Guo, Shanshan Li, Xiaoyan Liu, Haixia Zhang. (2018) A boronate-decorated porous carbon material derived from a zinc-based metal–organic framework for enrichment of cis-diol-containing nucleosides. NEW JOURNAL OF CHEMISTRY, 42 (3): (2288-2294). [PMID:] [10.1039/C7NJ04575A] |
14. Shuxia Wang, Huihui Li, Xiujuan Guan, Ting Cheng, Haixia Zhang. (2017) Silica – Boronate affinity material for quick enrichment of intracellular nucleosides. TALANTA, 166 (148). [PMID:28213215] [10.1016/j.talanta.2017.01.048] |
15. Huihui Li, Ting Cheng, Shuxia Wang, Xinyue Zhu, Haixia Zhang. (2016) High-efficiency extraction of nucleosides based on the combination of self-assembly ionic liquid layer and boronic acid-functionalized attapulgite. TALANTA, 153 (71). [PMID:27130092] [10.1016/j.talanta.2016.02.004] |
16. Chaozhan Wang, Huanhuan Xu, Yinmao Wei. (2016) The preparation of high-capacity boronate affinity adsorbents by surface initiated reversible addition fragmentation chain transfer polymerization for the enrichment of ribonucleosides in serum. ANALYTICA CHIMICA ACTA, 902 (115). [PMID:26703260] [10.1016/j.aca.2015.11.013] |
17. Li-li Zhang, Yong-liang Bai, Shu-lan Shu, Da-wei Qian, Zhen Ou-yang, Li Liu, Jin-ao Duan. (2014) Simultaneous quantitation of nucleosides, nucleobases, amino acids, and alkaloids in mulberry leaf by ultra high performance liquid chromatography with triple quadrupole tandem mass spectrometry. JOURNAL OF SEPARATION SCIENCE, 37 (11): (1265-1275). [PMID:24616434] [10.1002/jssc.201301267] |
18. Sheng Guo, Jin-ao Duan, Dawei Qian, Hanqing Wang, Yuping Tang, Yefei Qian, Dawei Wu, Shulan Su, Erxin Shang. (2013) Hydrophilic interaction ultra-high performance liquid chromatography coupled with triple quadrupole mass spectrometry for determination of nucleotides, nucleosides and nucleobases in Ziziphus plants. JOURNAL OF CHROMATOGRAPHY A, 1301 (147). [PMID:23800804] [10.1016/j.chroma.2013.05.074] |
19. Hengye Li,Xuemeng Zhang,Lin Zhang,Xiaojin Wang,Fenying Kong,Dahe Fan,Lei Li,Wei Wang. (2016-10-30) Preparation of a boronate affinity silica stationary phase with enhanced binding properties towards cis-diol compounds.. Journal of chromatography. A, 1473 (90-98). [PMID:27776772] |