2'-Deoxyadenosine Anhydrous - >98.0%(HPLC)(T), high purity , CAS No.958-09-8

8 Citations
Item Number
D155667
Grouped product items
SKUSizeAvailabilityPrice Qty
D155667-5g
5g
In stock
$26.90
D155667-25g
25g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$117.90

Basic Description

Synonyms2'-deoxyadenosine | 958-09-8 | deoxyadenosine | Adenyldeoxyriboside | Adenine deoxyribose | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol | ADENOSINE, 2'-DEOXY- | Desoxyadenosine | 2-Deoxyadenosine | Adenine deoxyribonucleoside | CCRIS 1782 | NSC 1
Specifications & PurityMoligand™, ≥98%(HPLC)(T)
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Product Description

2′-Deoxyadenosine, also called DNA nucleoside A, is a nucleoside adenosine derivative. 2′-Deoxyadenosine pairs with deoxythymidine (T) in double-stranded DNA. In absence of adenosine deaminase (ADA) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease (ADA-SCID).
A nucleoside adenosine derivative with mutagenic properties

Associated Targets(Human)

DCK Tchem Deoxycytidine kinase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TK1 Tchem Thymidine kinase, cytosolic (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA2A Tclin Adenosine receptor A2a (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA2B Tclin Adenosine receptor A2b (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADCY5 Tchem Adenylate cyclase type 5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADA Tclin Adenosine deaminase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA1 Tclin Adenosine receptor A1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA3 Tchem Adenosine receptor A3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADA Tclin Adenosine deaminase (129 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA2A Tclin Adenosine A2a receptor (16305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA2B Tclin Adenosine A2b receptor (7672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DCK Tchem Deoxycytidine kinase (530 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TK1 Tchem Thymidine kinase, cytosolic (627 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MT4 (17854 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATH-8 cell line (300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HaCaT (4069 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEL (6614 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Adcy5 Adenylate cyclase type V (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichomonas vaginalis (2376 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 2 (4932 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human respirovirus 3 (1674 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vaccinia virus (4609 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 1 (11089 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hepatitis B virus (7925 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Poliovirus 1 (1274 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Semliki Forest virus (705 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sindbis virus (1599 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vesicular stomatitis virus (4460 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Coxsackievirus B4 (2249 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Respiratory syncytial virus (3434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Duck hepatitis B virus (235 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDCK (10148 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
C6 (2371 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L6 (7924 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
dak Deoxyadenosine kinase (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mammalian orthoreovirus 1 (1523 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Woodchuck hepatitis virus (122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
INCHI InChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
InChi Key OLXZPDWKRNYJJZ-RRKCRQDMSA-N
Canonical SMILES C1C(C(OC1N2C=NC3=C(N=CN=C32)N)CO)O
Isomeric SMILES C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)O
RTECS AU7358600
PubChem CID 13730
Molecular Weight 251.25
Reaxy-Rn 91015

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

5 results found

Lot NumberCertificate TypeDateItem
F2418377Certificate of AnalysisJun 12, 2024 D155667
F2418378Certificate of AnalysisJun 12, 2024 D155667
F2418376Certificate of AnalysisJun 12, 2024 D155667
F2418379Certificate of AnalysisJun 12, 2024 D155667
B2207276Certificate of AnalysisJan 07, 2022 D155667

Chemical and Physical Properties

SensitivityAir Sensitive,Heat Sensitive
Specific Rotation[α]-27° (C=0.5,H2O)
Melt Point(°C)191 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

RTECS AU7358600
Reaxy-Rn 91015

Related Documents

Citations of This Product

1. Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan.  (2024)  Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers.  SEPARATION AND PURIFICATION TECHNOLOGY,  330  (125346).  [PMID:15220430]
2. Ziyi Wang, Li Xu, Ting Zou, Furong Tang, Juan Zhang.  (2024)  Fabrication of boronic acid-functionalized covalent organic framework for the selective adsorption of cis-diol-containing compounds.  APPLIED SURFACE SCIENCE,  644  (13): (158698).  [PMID:28500754]
3. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang.  (2023)  A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr..  JOURNAL OF SEPARATION SCIENCE,  46  (21): (2300090).  [PMID:37688342]
4. Ziyi Wang, Ting Zou, Shitao Feng, Fengshou Wu, Juan Zhang.  (2023)  Boronic acid-functionalized magnetic porphyrin-based covalent organic framework for selective enrichment of cis-diol-containing nucleosides.  ANALYTICA CHIMICA ACTA,  1278  (341691).  [PMID:37709444]
5. Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan.  (2023)  Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine.  SEPARATION AND PURIFICATION TECHNOLOGY,  312  (123384).  [PMID:]
6. Pan Wang, Mengdei Zhou, Zhuangxin Wei, Lu Liu, Tao Cheng, Xiaohua Tian, Jianming Pan.  (2023)  Preparation of bowl-shaped polydopamine surface imprinted polymer composite adsorbent for specific separation of 2′-deoxyadenosine.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,  60  (69).  [PMID:]
7. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan.  (2022)  Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine.  SEPARATION AND PURIFICATION TECHNOLOGY,  302  (122048).  [PMID:]
8. Hengye Li,Xuemeng Zhang,Lin Zhang,Xiaojin Wang,Fenying Kong,Dahe Fan,Lei Li,Wei Wang.  (2016-10-30)  Preparation of a boronate affinity silica stationary phase with enhanced binding properties towards cis-diol compounds..  Journal of chromatography. A,  1473  (90-98).  [PMID:27776772]

References

1. Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan.  (2024)  Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers.  SEPARATION AND PURIFICATION TECHNOLOGY,  330  (125346).  [PMID:15220430]
2. Ziyi Wang, Li Xu, Ting Zou, Furong Tang, Juan Zhang.  (2024)  Fabrication of boronic acid-functionalized covalent organic framework for the selective adsorption of cis-diol-containing compounds.  APPLIED SURFACE SCIENCE,  644  (13): (158698).  [PMID:28500754]
3. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang.  (2023)  A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr..  JOURNAL OF SEPARATION SCIENCE,  46  (21): (2300090).  [PMID:37688342]
4. Ziyi Wang, Ting Zou, Shitao Feng, Fengshou Wu, Juan Zhang.  (2023)  Boronic acid-functionalized magnetic porphyrin-based covalent organic framework for selective enrichment of cis-diol-containing nucleosides.  ANALYTICA CHIMICA ACTA,  1278  (341691).  [PMID:37709444]
5. Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan.  (2023)  Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine.  SEPARATION AND PURIFICATION TECHNOLOGY,  312  (123384).  [PMID:]
6. Pan Wang, Mengdei Zhou, Zhuangxin Wei, Lu Liu, Tao Cheng, Xiaohua Tian, Jianming Pan.  (2023)  Preparation of bowl-shaped polydopamine surface imprinted polymer composite adsorbent for specific separation of 2′-deoxyadenosine.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,  60  (69).  [PMID:]
7. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan.  (2022)  Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine.  SEPARATION AND PURIFICATION TECHNOLOGY,  302  (122048).  [PMID:]
8. Hengye Li,Xuemeng Zhang,Lin Zhang,Xiaojin Wang,Fenying Kong,Dahe Fan,Lei Li,Wei Wang.  (2016-10-30)  Preparation of a boronate affinity silica stationary phase with enhanced binding properties towards cis-diol compounds..  Journal of chromatography. A,  1473  (90-98).  [PMID:27776772]

Solution Calculators