2′-Deoxycytidine (deoxyC) forms dCTP upon phosphorylation which is used to synthesis DNA via various DNA polymerases or reverse transcriptases. DeoxyC is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2′-deoxyuridine. Deoxy
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Store at -20°C
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Product Description
application：
2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2′-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2′-deoxyuridine. 2′-Deoxycytidine is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK).
product description：
2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides containing cytosine as the nucleobase. It is found in the blood, feces, and urine.
application：
2′-Deoxycytidine has been used:
as a substrate for Trypanosoma brucei cytidine deaminase (TbCDA) to measure its activity
as a standard in the isolation and quantification of metabolite levels in murine tumor interstitial fluid by liquid chromatography-mass spectrometry (LC–MS)
to study the role of autophagy in response to oncogenes and DNA replication stress
1.Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan. (2024) Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers. SEPARATION AND PURIFICATION TECHNOLOGY, 330 (125346). [PMID:15220430]
2.Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan. (2023) Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 312 (123384). [PMID:]
3.Pan Wang, Mengdei Zhou, Zhuangxin Wei, Lu Liu, Tao Cheng, Xiaohua Tian, Jianming Pan. (2023) Preparation of bowl-shaped polydopamine surface imprinted polymer composite adsorbent for specific separation of 2′-deoxyadenosine. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 60 (69). [PMID:]
4.Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan. (2022) Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 302 (122048). [PMID:]
5.Hengye Li,Xuemeng Zhang,Lin Zhang,Hui Cang,Fenying Kong,Dahe Fan,Wei Wang. (2018-04-13) Hyperbranched Polyglycerol Functionalized Silica Stationary Phase for Hydrophilic Interaction Liquid Chromatography.. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 34 ((4)):(433-438). [PMID:29643306]
References
1.Joshua J Klaene, Caroline Flarakos, James Glick, Jennifer T Barret, Helmut Zarbl, Paul Vouros,. (2015-11-27) Tracking matrix effects in the analysis of DNA adducts of polycyclic aromatic hydrocarbons.. Journal of chromatography. A, ( 112-123 ). [PMID:26607319]
2.Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan. (2024) Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers. SEPARATION AND PURIFICATION TECHNOLOGY, 330 (125346). [PMID:15220430]
3.Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan. (2023) Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 312 (123384). [PMID:]
4.Pan Wang, Mengdei Zhou, Zhuangxin Wei, Lu Liu, Tao Cheng, Xiaohua Tian, Jianming Pan. (2023) Preparation of bowl-shaped polydopamine surface imprinted polymer composite adsorbent for specific separation of 2′-deoxyadenosine. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 60 (69). [PMID:]
5.Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan. (2022) Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 302 (122048). [PMID:]
6.Hengye Li,Xuemeng Zhang,Lin Zhang,Hui Cang,Fenying Kong,Dahe Fan,Wei Wang. (2018-04-13) Hyperbranched Polyglycerol Functionalized Silica Stationary Phase for Hydrophilic Interaction Liquid Chromatography.. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 34 ((4)):(433-438). [PMID:29643306]
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