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2′-Deoxyguanosine hydrate - 99%, high purity , CAS No.961-07-9

≥99%

CAS#: 961-07-9
Formula: C₁₀H₁₃N₅O₄·xH₂O
Molecular Weight: 267.24(anhydrous basis)
MDL number: MFCD00150760
PubChem CID: 135398592

Item Number

D100364

Grouped product items
SKU	Size	Availability	Price
D100364-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$9.90
D100364-500mg	500mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$32.90
D100364-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$50.90
D100364-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$147.90
D100364-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$539.90
D100364-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$639.90

Purine nucleoside.

View related series

Pyrimidines Six-Membered Heterocyclic Compounds

Basic Description

Synonyms	2'-deoxyguanosine\|deoxyguanosine\|961-07-9\|Guanosine, 2'-deoxy-\|2-Deoxyguanosine\|Guanine deoxy nucleoside\|Guanine deoxyriboside\|2'-DEOXY-GUANOSINE\|2(acute)-Deoxyguanosine\|663615-45-0\|2'-Desoxyguanosine\|2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetra
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Purine nucleoside that upon sequential phosphoylation forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesise DNA.
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

DCK Tchem Deoxycytidine kinase 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TK1 Tchem Thymidine kinase, cytosolic 0 Activities

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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MAPT Tclin Microtubule-associated protein tau 0 Activities

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ATAD5 Tbio ATPase family AAA domain-containing protein 5 0 Activities

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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

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PNP Tclin Purine nucleoside phosphorylase 0 Activities

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Names and Identifiers

IUPAC Name	2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
INCHI	InChI=1S/C10H13N5O4/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,6+/m0/s1
InChi Key	YKBGVTZYEHREMT-KVQBGUIXSA-N
Canonical SMILES	C1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O
Isomeric SMILES	C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)CO)O
WGK Germany	3
RTECS	MF8760000
Alternate CAS	207121-55-9
PubChem CID	135398592
Molecular Weight	267.24(anhydrous basis)
Reaxy-Rn	760398

Certificates

Certificate of Analysis(COA)

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16 results found

Lot Number	Certificate Type	Date	Item
F2417252	Certificate of Analysis	Jun 04, 2024	D100364
F2417269	Certificate of Analysis	Jun 04, 2024	D100364
D2425285	Certificate of Analysis	Mar 21, 2024	D100364
D2425287	Certificate of Analysis	Mar 21, 2024	D100364
L2220220	Certificate of Analysis	Nov 29, 2022	D100364
L2220221	Certificate of Analysis	Nov 29, 2022	D100364
L2220238	Certificate of Analysis	Nov 29, 2022	D100364
L2220239	Certificate of Analysis	Nov 29, 2022	D100364
I2207335	Certificate of Analysis	Jul 22, 2022	D100364
I2207336	Certificate of Analysis	Jul 22, 2022	D100364
I2207337	Certificate of Analysis	Jul 22, 2022	D100364
I2207338	Certificate of Analysis	Jul 22, 2022	D100364
I2207339	Certificate of Analysis	Jul 22, 2022	D100364
F2228232	Certificate of Analysis	May 28, 2022	D100364
F2228234	Certificate of Analysis	May 28, 2022	D100364
C2222031	Certificate of Analysis	Mar 25, 2022	D100364

Solubility

Slightly soluble in water.

Sensitivity

air sensitive;Moisture sensitive

Specific Rotation[α]

-42 ° (C=0.2, 1mol/L NaOH)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RTECS	MF8760000
Reaxy-Rn	760398

References

1. Camila Donato Mahl, Camile Saul Behling, Fernanda S Hackenhaar, Mélany Natuane de Carvalho e Silva, Jordana Putti, Tiago B Salomon, Sydney Hartz Alves, Alexandre Fuentefria, Mara S Benfato,. (2015-05-04) Induction of ROS generation by fluconazole in Candida glabrata: activation of antioxidant enzymes and oxidative DNA damage.. Diagnostic microbiology and infectious disease, 82 ((3)): ( 203-208 ). [PMID:25935629]

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