2′-Deoxyguanosine hydrate - 99%, high purity , CAS No.961-07-9

  • ≥99%
Item Number
D100364
Grouped product items
SKUSizeAvailabilityPrice Qty
D100364-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$9.90
D100364-500mg
500mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$32.90
D100364-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$50.90
D100364-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$147.90
D100364-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$425.90
D100364-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$849.90

Purine nucleoside.

Basic Description

Synonyms1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid, AldrichCPR | CHEBI:17172 | 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one | C00330 | SR-01000906476-1 | 6H-purin-6-one, 2-amino-9-(2-deoxy-beta-D-erythro-pentofuranos
Specifications & Purity≥99%
Biochemical and Physiological MechanismsPurine nucleoside that upon sequential phosphoylation forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesise DNA.
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

DCK Tchem Deoxycytidine kinase (530 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TK1 Tchem Thymidine kinase, cytosolic (627 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCRF-HSB-2 (188 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MT4 (17854 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HaCaT (4069 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pnp Purine nucleoside phosphorylase (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 2 (4932 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 3 (4092 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human betaherpesvirus 5 (5122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 1 (11089 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
C6 (2371 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L6 (7924 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
dgk Deoxyguanosine kinase (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
INCHI InChI=1S/C10H13N5O4/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,6+/m0/s1
InChi Key YKBGVTZYEHREMT-KVQBGUIXSA-N
Canonical SMILES C1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O
Isomeric SMILES C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)CO)O
WGK Germany 3
RTECS MF8760000
Alternate CAS 207121-55-9
PubChem CID 135398592
Molecular Weight 267.24(anhydrous basis)
Reaxy-Rn 760398

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

18 results found

Lot NumberCertificate TypeDateItem
K2427591Certificate of AnalysisNov 08, 2024 D100364
K2427590Certificate of AnalysisNov 08, 2024 D100364
F2417252Certificate of AnalysisJun 04, 2024 D100364
F2417269Certificate of AnalysisJun 04, 2024 D100364
D2425285Certificate of AnalysisMar 21, 2024 D100364
D2425287Certificate of AnalysisMar 21, 2024 D100364
L2220239Certificate of AnalysisNov 29, 2022 D100364
L2220238Certificate of AnalysisNov 29, 2022 D100364
L2220221Certificate of AnalysisNov 29, 2022 D100364
L2220220Certificate of AnalysisNov 29, 2022 D100364
I2207338Certificate of AnalysisJul 22, 2022 D100364
I2207339Certificate of AnalysisJul 22, 2022 D100364
I2207337Certificate of AnalysisJul 22, 2022 D100364
I2207336Certificate of AnalysisJul 22, 2022 D100364
I2207335Certificate of AnalysisJul 22, 2022 D100364
F2228234Certificate of AnalysisMay 28, 2022 D100364
F2228232Certificate of AnalysisMay 28, 2022 D100364
C2222031Certificate of AnalysisMar 25, 2022 D100364

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Chemical and Physical Properties

SolubilitySlightly soluble in water.
Sensitivityair sensitive;Moisture sensitive
Specific Rotation[α]-42 ° (C=0.2, 1mol/L NaOH)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

WGK Germany 3
RTECS MF8760000
Reaxy-Rn 760398

Related Documents

Citations of This Product

1. Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan.  (2024)  Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers.  SEPARATION AND PURIFICATION TECHNOLOGY,  330  (125346).  [PMID:15220430] [10.1016/j.seppur.2023.125346]
2. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang.  (2023)  A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr..  JOURNAL OF SEPARATION SCIENCE,  46  (21): (2300090).  [PMID:37688342] [10.1002/jssc.202300090]
3. Xu Lian, Li Hui-Min, Lin Juan.  (2023)  Efficient synthesis of 2’-deoxyguanosine in one-pot cascade by employing an engineered purine nucleoside phosphorylase from Brevibacterium acetylicum.  WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,  39  (10): (1-9).  [PMID:37606812] [10.1007/s11274-023-03721-1]
4. Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan.  (2023)  Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine.  SEPARATION AND PURIFICATION TECHNOLOGY,  312  (123384).  [PMID:] [10.1016/j.seppur.2023.123384]
5. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan.  (2022)  Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine.  SEPARATION AND PURIFICATION TECHNOLOGY,  302  (122048).  [PMID:] [10.1016/j.seppur.2022.122048]
6. Xin Wen, Huahua Fan, Lihong Jing, Ming Deng, Xiaodan Huang, Tifeng Jiao, Li Zhang, Minghua Liu.  (2022)  Competitive induction of circularly polarized luminescence of CdSe/ZnS quantum dots in a nucleotide–amino acid hydrogel.  Materials Advances,  (1): (682-688).  [PMID:] [10.1039/D1MA00843A]
7. Chang Xiangwei, Zhang Zhenyu, Yan Hui, Su Shulan, Wei Dandan, Guo Sheng, Shang Erxin, Sun Xiaodong, Gui Shuangying, Duan Jinao.  (2021)  Discovery of Quality Markers of Nucleobases, Nucleosides, Nucleotides and Amino Acids for Chrysanthemi Flos From Different Geographical Origins Using UPLC–MS/MS Combined With Multivariate Statistical Analysis.  Frontiers in Chemistry,    [PMID:34422760] [10.3389/fchem.2021.689254]
8. Jia Ding, Fei Liu, Chunling Qi, Yunlei Zhou, Huanshun Yin, Shiyun Ai.  (2021)  Enhanced photoactivity of perovskite Bi4NbO8Cl/PTC-NH2 heterojunction and its application for photoelectrochemical sensing of DNA hydroxymethylation.  SENSORS AND ACTUATORS B-CHEMICAL,  344  (130211).  [PMID:] [10.1016/j.snb.2021.130211]
9. Ji-shuo Chang, Zhong-xiao Lin, Ya-juan Liu, Si-ming Yang, Yu Zhang, Xi-yong Yu.  (2021)  Ultra performance liquid chromatography–tandem mass spectrometry assay for the quantification of RNA and DNA methylation.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  197  (113969).  [PMID:33636646] [10.1016/j.jpba.2021.113969]
10. Shuangshou Wang, Zhendong He, Wenzhi Li, Jiayi Zhao, Tong Chen, Shimin Shao, Hongmei Chen.  (2020)  Reshaping of pipette tip: A facile and practical strategy for sorbent packing-free solid phase extraction.  ANALYTICA CHIMICA ACTA,  1100  (47).  [PMID:31987152] [10.1016/j.aca.2019.11.060]
11. Yuanyuan Xu, Yue Yang, Aifang Xue, Hao Chen, Shengqing Li.  (2018)  In situ precipitation of hydrous titanium dioxide for dispersive micro solid-phase extraction of nucleosides and their separation.  NEW JOURNAL OF CHEMISTRY,  42  (7): (4909-4914).  [PMID:] [10.1039/C7NJ04590E]
12. Chaozhan Wang, Huanhuan Xu, Yinmao Wei.  (2016)  The preparation of high-capacity boronate affinity adsorbents by surface initiated reversible addition fragmentation chain transfer polymerization for the enrichment of ribonucleosides in serum.  ANALYTICA CHIMICA ACTA,  902  (115).  [PMID:26703260] [10.1016/j.aca.2015.11.013]
13. Hengye Li,Xuemeng Zhang,Lin Zhang,Hui Cang,Fenying Kong,Dahe Fan,Wei Wang.  (2018-04-13)  Hyperbranched Polyglycerol Functionalized Silica Stationary Phase for Hydrophilic Interaction Liquid Chromatography..  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry,  34  ((4)): (433-438).  [PMID:29643306]

References

1. Camila Donato Mahl, Camile Saul Behling, Fernanda S Hackenhaar, Mélany Natuane de Carvalho e Silva, Jordana Putti, Tiago B Salomon, Sydney Hartz Alves, Alexandre Fuentefria, Mara S Benfato,.  (2015-05-04)  Induction of ROS generation by fluconazole in Candida glabrata: activation of antioxidant enzymes and oxidative DNA damage..  Diagnostic microbiology and infectious disease,  82  ((3)): ( 203-208 ).  [PMID:25935629]
2. Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan.  (2024)  Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers.  SEPARATION AND PURIFICATION TECHNOLOGY,  330  (125346).  [PMID:15220430] [10.1016/j.seppur.2023.125346]
3. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang.  (2023)  A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr..  JOURNAL OF SEPARATION SCIENCE,  46  (21): (2300090).  [PMID:37688342] [10.1002/jssc.202300090]
4. Xu Lian, Li Hui-Min, Lin Juan.  (2023)  Efficient synthesis of 2’-deoxyguanosine in one-pot cascade by employing an engineered purine nucleoside phosphorylase from Brevibacterium acetylicum.  WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,  39  (10): (1-9).  [PMID:37606812] [10.1007/s11274-023-03721-1]
5. Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan.  (2023)  Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine.  SEPARATION AND PURIFICATION TECHNOLOGY,  312  (123384).  [PMID:] [10.1016/j.seppur.2023.123384]
6. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan.  (2022)  Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine.  SEPARATION AND PURIFICATION TECHNOLOGY,  302  (122048).  [PMID:] [10.1016/j.seppur.2022.122048]
7. Xin Wen, Huahua Fan, Lihong Jing, Ming Deng, Xiaodan Huang, Tifeng Jiao, Li Zhang, Minghua Liu.  (2022)  Competitive induction of circularly polarized luminescence of CdSe/ZnS quantum dots in a nucleotide–amino acid hydrogel.  Materials Advances,  (1): (682-688).  [PMID:] [10.1039/D1MA00843A]
8. Chang Xiangwei, Zhang Zhenyu, Yan Hui, Su Shulan, Wei Dandan, Guo Sheng, Shang Erxin, Sun Xiaodong, Gui Shuangying, Duan Jinao.  (2021)  Discovery of Quality Markers of Nucleobases, Nucleosides, Nucleotides and Amino Acids for Chrysanthemi Flos From Different Geographical Origins Using UPLC–MS/MS Combined With Multivariate Statistical Analysis.  Frontiers in Chemistry,    [PMID:34422760] [10.3389/fchem.2021.689254]
9. Jia Ding, Fei Liu, Chunling Qi, Yunlei Zhou, Huanshun Yin, Shiyun Ai.  (2021)  Enhanced photoactivity of perovskite Bi4NbO8Cl/PTC-NH2 heterojunction and its application for photoelectrochemical sensing of DNA hydroxymethylation.  SENSORS AND ACTUATORS B-CHEMICAL,  344  (130211).  [PMID:] [10.1016/j.snb.2021.130211]
10. Ji-shuo Chang, Zhong-xiao Lin, Ya-juan Liu, Si-ming Yang, Yu Zhang, Xi-yong Yu.  (2021)  Ultra performance liquid chromatography–tandem mass spectrometry assay for the quantification of RNA and DNA methylation.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  197  (113969).  [PMID:33636646] [10.1016/j.jpba.2021.113969]
11. Shuangshou Wang, Zhendong He, Wenzhi Li, Jiayi Zhao, Tong Chen, Shimin Shao, Hongmei Chen.  (2020)  Reshaping of pipette tip: A facile and practical strategy for sorbent packing-free solid phase extraction.  ANALYTICA CHIMICA ACTA,  1100  (47).  [PMID:31987152] [10.1016/j.aca.2019.11.060]
12. Yuanyuan Xu, Yue Yang, Aifang Xue, Hao Chen, Shengqing Li.  (2018)  In situ precipitation of hydrous titanium dioxide for dispersive micro solid-phase extraction of nucleosides and their separation.  NEW JOURNAL OF CHEMISTRY,  42  (7): (4909-4914).  [PMID:] [10.1039/C7NJ04590E]
13. Chaozhan Wang, Huanhuan Xu, Yinmao Wei.  (2016)  The preparation of high-capacity boronate affinity adsorbents by surface initiated reversible addition fragmentation chain transfer polymerization for the enrichment of ribonucleosides in serum.  ANALYTICA CHIMICA ACTA,  902  (115).  [PMID:26703260] [10.1016/j.aca.2015.11.013]
14. Hengye Li,Xuemeng Zhang,Lin Zhang,Hui Cang,Fenying Kong,Dahe Fan,Wei Wang.  (2018-04-13)  Hyperbranched Polyglycerol Functionalized Silica Stationary Phase for Hydrophilic Interaction Liquid Chromatography..  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry,  34  ((4)): (433-438).  [PMID:29643306]

Solution Calculators