Grouped product items

SKU

Size

Availability

Price

Qty

D427161-1ml

1ml

Available within 4-8 weeks(?)

$59.90

Basic Description

Synonyms	2'-deoxyguanosine \| deoxyguanosine \| 961-07-9 \| Guanosine, 2'-deoxy- \| 2-Deoxyguanosine \| Guanine deoxy nucleoside \| Guanine deoxyriboside \| 2'-DEOXY-GUANOSINE \| 2(acute)-Deoxyguanosine \| 663615-45-0 \| 2'-Desoxyguanosine \| 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetra
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Purine nucleoside that upon sequential phosphoylation forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesise DNA.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

DCK Tchem Deoxycytidine kinase (530 Activities)

Discover Target: DCK

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TK1 Tchem Thymidine kinase, cytosolic (627 Activities)

Discover Target: TK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCRF-HSB-2 (188 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DU-145 (51482 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HL-60 (67320 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF7 (126967 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MT4 (17854 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HaCaT (4069 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)

Discover Target: ATAD5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)

Discover Target: IDH1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Pnp Purine nucleoside phosphorylase (4 Activities)

Discover Target: Pnp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Human alphaherpesvirus 2 (4932 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Human alphaherpesvirus 3 (4092 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Human betaherpesvirus 5 (5122 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Human alphaherpesvirus 1 (11089 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Human immunodeficiency virus 1 (70413 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RAW264.7 (28094 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

C6 (2371 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

L6 (7924 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

dgk Deoxyguanosine kinase (4 Activities)

Discover Target: dgk

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
INCHI	InChI=1S/C10H13N5O4/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,6+/m0/s1
InChi Key	YKBGVTZYEHREMT-KVQBGUIXSA-N
Canonical SMILES	C1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O
Isomeric SMILES	C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)CO)O
WGK Germany	3
RTECS	MF8760000
Alternate CAS	207121-55-9
PubChem CID	135398592
Molecular Weight	267.24(anhydrous basis)
Reaxy-Rn	760398

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Sensitivity	air sensitive;Moisture sensitive
Specific Rotation[α]	-42 ° (C=0.2, 1mol/L NaOH)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RTECS	MF8760000
Reaxy-Rn	760398

Citations of This Product

1. Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan. (2024) Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers. SEPARATION AND PURIFICATION TECHNOLOGY, 330 (125346). [PMID:15220430]
2. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang. (2023) A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr.. JOURNAL OF SEPARATION SCIENCE, 46 (21): (2300090). [PMID:37688342]
3. Xu Lian, Li Hui-Min, Lin Juan. (2023) Efficient synthesis of 2’-deoxyguanosine in one-pot cascade by employing an engineered purine nucleoside phosphorylase from Brevibacterium acetylicum. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 39 (10): (1-9). [PMID:37606812]
4. Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan. (2023) Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 312 (123384). [PMID:]
5. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan. (2022) Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 302 (122048). [PMID:]
6. Xin Wen, Huahua Fan, Lihong Jing, Ming Deng, Xiaodan Huang, Tifeng Jiao, Li Zhang, Minghua Liu. (2022) Competitive induction of circularly polarized luminescence of CdSe/ZnS quantum dots in a nucleotide–amino acid hydrogel. Materials Advances, 3 (1): (682-688). [PMID:]
7. Hengye Li,Xuemeng Zhang,Lin Zhang,Hui Cang,Fenying Kong,Dahe Fan,Wei Wang. (2018-04-13) Hyperbranched Polyglycerol Functionalized Silica Stationary Phase for Hydrophilic Interaction Liquid Chromatography.. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 34 ((4)): (433-438). [PMID:29643306]

References

1. Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan. (2024) Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers. SEPARATION AND PURIFICATION TECHNOLOGY, 330 (125346). [PMID:15220430]
2. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang. (2023) A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr.. JOURNAL OF SEPARATION SCIENCE, 46 (21): (2300090). [PMID:37688342]
3. Xu Lian, Li Hui-Min, Lin Juan. (2023) Efficient synthesis of 2’-deoxyguanosine in one-pot cascade by employing an engineered purine nucleoside phosphorylase from Brevibacterium acetylicum. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 39 (10): (1-9). [PMID:37606812]
4. Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan. (2023) Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 312 (123384). [PMID:]
5. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan. (2022) Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, 302 (122048). [PMID:]
6. Xin Wen, Huahua Fan, Lihong Jing, Ming Deng, Xiaodan Huang, Tifeng Jiao, Li Zhang, Minghua Liu. (2022) Competitive induction of circularly polarized luminescence of CdSe/ZnS quantum dots in a nucleotide–amino acid hydrogel. Materials Advances, 3 (1): (682-688). [PMID:]
7. Hengye Li,Xuemeng Zhang,Lin Zhang,Hui Cang,Fenying Kong,Dahe Fan,Wei Wang. (2018-04-13) Hyperbranched Polyglycerol Functionalized Silica Stationary Phase for Hydrophilic Interaction Liquid Chromatography.. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 34 ((4)): (433-438). [PMID:29643306]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

2′-Deoxyguanosine hydrate - 10mM in DMSO, high purity , CAS No.961-07-9