2′-Fluoro-2′-deoxycytidine - >98.0%(T), high purity , CAS No.10212-20-1

  • ≥98%(T)
Item Number
F119524
Grouped product items
SKUSizeAvailabilityPrice Qty
F119524-200mg
200mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$12.90
F119524-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$49.90
F119524-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$220.90

Basic Description

Synonyms4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one | AS-59691 | SMR001233493 | 2'-Deoxy-2'-fluorocytidine | 2'deoxy-2'-fluorocytidine | 2-Deoxy-2-fluorocytidine | AKOS015854842 | UNII-LCY080JPY9 | .beta.-D-2'-Deoxy-2'
Specifications & Purity≥98%(T)
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

application:

2'-Fluoro-2'-deoxycytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Fluoro-2'-deoxycytidine has been shown to inhibit Borna Disease virus replication and spread.

Associated Targets(Human)

DCK Tchem Deoxycytidine kinase (530 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MT4 (17854 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLRMT Tbio DNA-directed RNA polymerase, mitochondrial (57 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLG Tchem DNA polymerase subunit gamma-1/gamma-2 (16 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Cda Cytidine deaminase (37 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hepatitis C virus (23859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Measles morbillivirus (693 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
INCHI InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s1
InChi Key NVZFZMCNALTPBY-XVFCMESISA-N
Canonical SMILES C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)F
Isomeric SMILES C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)F
WGK Germany 3
PubChem CID 101507
Molecular Weight 245.21
Reaxy-Rn 619217

Certificates

Certificate of Analysis(COA)

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1 results found

Lot NumberCertificate TypeDateItem
I1409102Certificate of AnalysisJun 24, 2022 F119524

Chemical and Physical Properties

SolubilitySoluble in DMSO, Methanol.
Specific Rotation[α]80° (C=1,MeOH)
Melt Point(°C)167°C(lit.)

Safety and Hazards(GHS)

WGK Germany 3
Reaxy-Rn 619217

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