Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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H133672-1mg | 1mg | In stock | $85.90 | |
H133672-5mg | 5mg | In stock | $323.90 | |
H133672-10mg | 10mg | In stock | $603.90 | |
H133672-25mg | 25mg | In stock | $1,357.90 | |
H133672-50mg | 50mg | In stock | $2,443.90 |
Cytochrome P450 metabolite of estradiol
Synonyms | 2-hydroxy-17beta-estradiol | 2-Hydroxyestradiol, analytical standard | 2-bromo-1-(4-fluorophenyl) ethanone | 2-Hydroxy-17 | BIDD:ER0098 | 2,3,17beta-Trihydroxy-1,3,5(10)-Estratriene | Epitope ID:159258 | ESTRADIOL METABOLITE (2-HYDROXYESTRADIOL) | BDBM502 |
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Specifications & Purity | ≥95% |
Biochemical and Physiological Mechanisms | Cytochrome P450 metabolite of estradiol with low affinity for estrogen receptors. Stimulates increase in β-adrenergic receptor density. Biological effects mediated by 2-methoxyestradiol after methylation of 2OHE by catechol-O-methyltransferase (COMT). |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488188993 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488188993 |
IUPAC Name | (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-2,3,17-triol |
INCHI | InChI=1S/C18H24O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,17,19-21H,2-7H2,1H3/t11-,12+,14-,17-,18-/m0/s1 |
InChi Key | DILDHNKDVHLEQB-XSSYPUMDSA-N |
Canonical SMILES | CC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)O)O |
Isomeric SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=C(C=C34)O)O |
WGK Germany | 3 |
RTECS | KG7675000 |
PubChem CID | 247304 |
Molecular Weight | 288.38 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
C2328625 | Certificate of Analysis | Jan 06, 2023 | H133672 |
C2328720 | Certificate of Analysis | Jan 06, 2023 | H133672 |
C2328735 | Certificate of Analysis | Jan 06, 2023 | H133672 |
C2328765 | Certificate of Analysis | Jan 06, 2023 | H133672 |
C2328831 | Certificate of Analysis | Jan 06, 2023 | H133672 |
C2328841 | Certificate of Analysis | Jan 06, 2023 | H133672 |
C2328972 | Certificate of Analysis | Jan 06, 2023 | H133672 |
C2328975 | Certificate of Analysis | Jan 06, 2023 | H133672 |
C2329145 | Certificate of Analysis | Jan 06, 2023 | H133672 |
C2329146 | Certificate of Analysis | Jan 06, 2023 | H133672 |
A2304080 | Certificate of Analysis | Dec 21, 2022 | H133672 |
Solubility | ≤20mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide |
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Pictogram(s) | GHS08 |
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Signal | Warning |
Hazard Statements | H351:Suspected of causing cancer |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. |
WGK Germany | 3 |
RTECS | KG7675000 |