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SKU

Size

Availability

Price

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H120323-5g

In stock

$14.90

H120323-10g

10g

In stock

$22.90

H120323-25g

25g

In stock

$43.90

H120323-100g

100g

In stock

$157.90

H120323-250g

250g

In stock

$296.90

Basic Description

Synonyms	SCHEMBL129889 \| SY012884 \| 2-Hydroxy-5-nitrobenzoic acid, 99% \| 5-nitro salicyclic acid \| 5-nitro-2-oxidanyl-benzoic acid \| 5-NITROSALICYCLIC ACID \| DTXSID2059142 \| A845661 \| W-100125 \| 82L9G7FYZ3 \| NSC183 \| NSC-183 \| AI3-08840 \| CS-W017068 \| AK-918/40744
Specifications & Purity	≥98%
Shipped In	Normal
Product Description	2-Hydroxy-5-nitrobenzoic acid inhibits the activity of wild type-bovine low Mr protein tyrosine phosphatase. The inhibition constant has been evaluated.

Associated Targets(Human)

SLC26A4 Tbio Pendrin (0 Activities)

Discover Target: SLC26A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HEK293 (82097 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Colon (26 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488180381
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488180381
IUPAC Name	2-hydroxy-5-nitrobenzoic acid
INCHI	InChI=1S/C7H5NO5/c9-6-2-1-4(8(12)13)3-5(6)7(10)11/h1-3,9H,(H,10,11)
InChi Key	PPDRLQLKHRZIJC-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=C(C=C1[N+](=O)[O-])C(=O)O)O
Isomeric SMILES	C1=CC(=C(C=C1[N+](=O)[O-])C(=O)O)O
WGK Germany	3
PubChem CID	7318
Molecular Weight	183.12
Beilstein	2213719
Reaxy-Rn	2213719

Certificates

Certificate of Analysis(COA)

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8 results found

Lot Number	Certificate Type	Date	Item
K2421161	Certificate of Analysis	Jul 06, 2024	H120323
C1911189	Certificate of Analysis	Jan 05, 2023	H120323
G2320111	Certificate of Analysis	Jun 10, 2022	H120323
H2205233	Certificate of Analysis	Jun 10, 2022	H120323
H2205234	Certificate of Analysis	Jun 10, 2022	H120323
H2205238	Certificate of Analysis	Jun 10, 2022	H120323
H2205239	Certificate of Analysis	Jun 10, 2022	H120323
H2205240	Certificate of Analysis	Jun 10, 2022	H120323

Chemical and Physical Properties

Solubility	Soluble in water 1g/1475ml
Melt Point(°C)	236°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	2213719
Merck Index	6631

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jiayue Dong, Peizeng Yang, Gregory V. Korshin, Junhe Lu. (2023) Bromide Catalyzes the Transformation of Nitrite by Sulfate Radical Oxidation. ACS ES&T Water, 3 (9): (3105–3112). [PMID:] [10.1021/acsestwater.3c00257]
2. Jiayue Dong, Peizeng Yang, Jing Chen, Yuefei Ji, Junhe Lu. (2022) Nitrophenolic byproducts formation during sulfate radical oxidation and their fate in simulated drinking water treatment processes. WATER RESEARCH, 224 (119054). [PMID:36088770] [10.1016/j.watres.2022.119054]
3. Kai Sun, Jiaying Yu, Jinzhong Hu, Jian Chen, Jia Song, Zhixin Chen, Zhuoer Cai, Zhuoxuan Lu, Liming Zhang, Zhifei Wang. (2022) Salicylic acid-based hypoxia-responsive chemodynamic nanomedicines boost antitumor immunotherapy by modulating immunosuppressive tumor microenvironment. Acta Biomaterialia, 148 (230). [PMID:35724919] [10.1016/j.actbio.2022.06.026]
4. Xu Gao, Qi Zhang, Ziyi Yang, Yuefei Ji, Jing Chen, Junhe Lu. (2022) Formation of Nitrophenolic Byproducts during UV-Activated Peroxydisulfate Oxidation in the Presence of Nitrate. ACS ES&T Engineering, 2 (2): (222–231). [PMID:] [10.1021/acsestengg.1c00356]
5. Qi Zhou, Xuelin Dong, Binbin Zhang, Shan Lu, Xinwei Zhang, Qin Wang, Yonggui Liao, Yajiang Yang, Hong Wang. (2021) Luminescence sensitization of terbium-loaded supramolecular gels by hydroxybenzoic acids and used for salicylates sensing. TALANTA, 225 (122061). [PMID:33592780] [10.1016/j.talanta.2020.122061]
6. Peizeng Yang, Li Qian, Yan Cheng, Yuefei Ji, Junhe Lu, Deyang Kong. (2021) Formation of nitrophenolic byproducts in soils subjected to sulfate radical oxidation. CHEMICAL ENGINEERING JOURNAL, 403 (126316). [PMID:] [10.1016/j.cej.2020.126316]
7. Yan Yan, Jinyao Sun, Xianting Xie, Pengchong Wang, Ying Sun, Yalin Dong, Jianfeng Xing. (2018) Colon-targeting mutual prodrugs of 5-aminosalicylic acid and butyrate for the treatment of ulcerative colitis. RSC Advances, 8 (5): (2561-2574). [PMID:35541446] [10.1039/C7RA13011B]

References

1. David Calligaris,Daniel R Feldman,Isaiah Norton,Olutayo Olubiyi,Armen N Changelian,Revaz Machaidze,Matthew L Vestal,Edward R Laws,Ian F Dunn,Sandro Santagata,Nathalie Y R Agar. (2015-07-29) MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation.. Proceedings of the National Academy of Sciences of the United States of America, 112 ((32)): (9978-9983). [PMID:26216958]
2. Sookjin Kang,Wooseong Kim,Seongkeun Jeong,Yonghyun Lee,Joon Nam,Sunyoung Lee,Yunjin Jung. (2017-05-06) Oxidized 5-aminosalicylic acid activates Nrf2-HO-1 pathway by covalently binding to Keap1: Implication in anti-inflammatory actions of 5-aminosalicylic acid.. Free radical biology & medicine, 108 (715-724). [PMID:28473247]
3. Timotej Strmeň,Vladimír Vrkoslav,Zuzana Bosáková,Josef Cvačka. (2020-01-09) Atmospheric pressure chemical ionization mass spectrometry at low flow rates: Importance of ion source housing.. Rapid communications in mass spectrometry : RCM, 34 ((10)): (e8722-e8722). [PMID:31912928]
4. Keishiro Nagoshi,Mariko Yamakoshi,Kenya Sakamoto,Mitsuo Takayama. (2018-04-21) Specific Cα-C Bond Cleavage of β-Carbon-Centered Radical Peptides Produced by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry.. Journal of the American Society for Mass Spectrometry, 29 ((7)): (1473-1483). [PMID:29675742]
5. Assala Lamaa,Jonathan Humbert,Marion Aguirrebengoa,Xue Cheng,Estelle Nicolas,Jacques Côté,Didier Trouche. (2020-02-29) Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation.. eLife, 9 [PMID:32109204]
6. Jiayue Dong, Peizeng Yang, Gregory V. Korshin, Junhe Lu. (2023) Bromide Catalyzes the Transformation of Nitrite by Sulfate Radical Oxidation. ACS ES&T Water, 3 (9): (3105–3112). [PMID:] [10.1021/acsestwater.3c00257]
7. Jiayue Dong, Peizeng Yang, Jing Chen, Yuefei Ji, Junhe Lu. (2022) Nitrophenolic byproducts formation during sulfate radical oxidation and their fate in simulated drinking water treatment processes. WATER RESEARCH, 224 (119054). [PMID:36088770] [10.1016/j.watres.2022.119054]
8. Kai Sun, Jiaying Yu, Jinzhong Hu, Jian Chen, Jia Song, Zhixin Chen, Zhuoer Cai, Zhuoxuan Lu, Liming Zhang, Zhifei Wang. (2022) Salicylic acid-based hypoxia-responsive chemodynamic nanomedicines boost antitumor immunotherapy by modulating immunosuppressive tumor microenvironment. Acta Biomaterialia, 148 (230). [PMID:35724919] [10.1016/j.actbio.2022.06.026]
9. Xu Gao, Qi Zhang, Ziyi Yang, Yuefei Ji, Jing Chen, Junhe Lu. (2022) Formation of Nitrophenolic Byproducts during UV-Activated Peroxydisulfate Oxidation in the Presence of Nitrate. ACS ES&T Engineering, 2 (2): (222–231). [PMID:] [10.1021/acsestengg.1c00356]
10. Qi Zhou, Xuelin Dong, Binbin Zhang, Shan Lu, Xinwei Zhang, Qin Wang, Yonggui Liao, Yajiang Yang, Hong Wang. (2021) Luminescence sensitization of terbium-loaded supramolecular gels by hydroxybenzoic acids and used for salicylates sensing. TALANTA, 225 (122061). [PMID:33592780] [10.1016/j.talanta.2020.122061]
11. Peizeng Yang, Li Qian, Yan Cheng, Yuefei Ji, Junhe Lu, Deyang Kong. (2021) Formation of nitrophenolic byproducts in soils subjected to sulfate radical oxidation. CHEMICAL ENGINEERING JOURNAL, 403 (126316). [PMID:] [10.1016/j.cej.2020.126316]
12. Yan Yan, Jinyao Sun, Xianting Xie, Pengchong Wang, Ying Sun, Yalin Dong, Jianfeng Xing. (2018) Colon-targeting mutual prodrugs of 5-aminosalicylic acid and butyrate for the treatment of ulcerative colitis. RSC Advances, 8 (5): (2561-2574). [PMID:35541446] [10.1039/C7RA13011B]

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2-Hydroxy-5-nitrobenzoic acid - >98.0%, high purity , CAS No.96-97-9

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator