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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | salicyl alcohol | 2-HYDROXYBENZYL ALCOHOL | 90-01-7 | 2-(Hydroxymethyl)phenol | Saligenin | Benzenemethanol, 2-hydroxy- | o-Hydroxybenzyl alcohol | Saligenol | 2-Methylolphenol | Diathesin | o-Methylolphenol | 2-Hydroxymethylphenol | o-(Hydroxymethyl)phenol | 2-Hydroxybenzenemetha |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | 2-Hydroxybenzyl alcohol participates in the selective ring opening reaction of 4H-1,3,2-benzodioxasilines. |
Associated Targets(Human)
SLC26A4 Tbio Pendrin (0 Activities)
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (0 Activities)
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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)
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ARG1 Tchem Arginase-1 (0 Activities)
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CCRF-CEM (65223 Activities)
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HEK293 (82097 Activities)
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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
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SLC26A4 Tbio Pendrin (86 Activities)
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Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
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Plasmodium falciparum (966862 Activities)
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L1210 (27553 Activities)
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rep Replicase polyprotein 1ab (378 Activities)
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ARG1 Arginase-1 (70 Activities)
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SARS-CoV-2 (38078 Activities)
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Names and Identifiers
| IUPAC Name | 2-(hydroxymethyl)phenol |
|---|---|
| INCHI | InChI=1S/C7H8O2/c8-5-6-3-1-2-4-7(6)9/h1-4,8-9H,5H2 |
| InChi Key | CQRYARSYNCAZFO-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC=C(C(=C1)CO)O |
| Isomeric SMILES | C1=CC=C(C(=C1)CO)O |
| WGK Germany | 3 |
| RTECS | DO6430000 |
| PubChem CID | 5146 |
| Molecular Weight | 124.14 |
| Beilstein | 1907195 |
| Reaxy-Rn | 1907195 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Sensitivity | Light sensitive. |
|---|---|
| Melt Point(°C) | 87°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| RTECS | DO6430000 |
| Reaxy-Rn | 1907195 |
| Merck Index | 8325 |
Related Documents
Citations of This Product
| 1. An Zhidong, Yang Piaoping, Duan Delong, Li Jiang, Wan Tong, Kong Yue, Caratzoulas Stavros, Xiang Shuting, Liu Jiaxing, Huang Lei, Frenkel Anatoly I., Jiang Yuan-Ye, Long Ran, Li Zhenxing, Vlachos Dionisios G.. (2023) Highly active, ultra-low loading single-atom iron catalysts for catalytic transfer hydrogenation. Nature Communications, 14 (1): (1-12). [PMID:37863924] |
| 2. Weiwei Yang, Mao Peng, Ye Lv, Mengya Sun, Jinli Zhang, Wei Li, Yan Fu. (2023) Selective electrooxidation of 2-hydroxybenzyl alcohol coupled with H2 production promoted by surface reconstruction of β-Ni(OH)2 nanosheets. CHEMICAL ENGINEERING JOURNAL, 475 (16): (146138). [PMID:14761976] |
| 3. Peng Xie, Wang Zhang, Wugao Wu, Zhuanglin Shen, Mingliang Wang, Yuxiao Lai, Yantao Chen, Zhongfan Jia. (2022) Phenoxyl mediators improve enzymatic degradation of organic pollutants: Effect and mechanism. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 215 (606). [PMID:35750102] |
References
| 1. An Zhidong, Yang Piaoping, Duan Delong, Li Jiang, Wan Tong, Kong Yue, Caratzoulas Stavros, Xiang Shuting, Liu Jiaxing, Huang Lei, Frenkel Anatoly I., Jiang Yuan-Ye, Long Ran, Li Zhenxing, Vlachos Dionisios G.. (2023) Highly active, ultra-low loading single-atom iron catalysts for catalytic transfer hydrogenation. Nature Communications, 14 (1): (1-12). [PMID:37863924] |
| 2. Weiwei Yang, Mao Peng, Ye Lv, Mengya Sun, Jinli Zhang, Wei Li, Yan Fu. (2023) Selective electrooxidation of 2-hydroxybenzyl alcohol coupled with H2 production promoted by surface reconstruction of β-Ni(OH)2 nanosheets. CHEMICAL ENGINEERING JOURNAL, 475 (16): (146138). [PMID:14761976] |
| 3. Peng Xie, Wang Zhang, Wugao Wu, Zhuanglin Shen, Mingliang Wang, Yuxiao Lai, Yantao Chen, Zhongfan Jia. (2022) Phenoxyl mediators improve enzymatic degradation of organic pollutants: Effect and mechanism. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 215 (606). [PMID:35750102] |