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2-Imidazolidinetione - 97%, high purity , CAS No.96-45-7

4 Citations

≥97%

CAS#: 96-45-7
Formula: C₃H₆N₂S
Molecular Weight: 102.16
Beilstein Registry Number: 106275
EC Number: 202-506-9
MDL number: MFCD00005276
PubChem CID: 2723650
PubChem SID: 488192171

Item Number

I109215

Grouped product items
SKU	Size	Availability	Price
I109215-25g	25g	In stock	$20.90
I109215-100g	100g	In stock	$24.90
I109215-250g	250g	In stock	$43.90
I109215-500g	500g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$78.90

View related series

Halogen free heterocyclic block Sulfur containing compounds

Basic Description

Synonyms	imidazolidine-2-thione \| 2-Imidazolidinethione \| Ethylenethiourea \| 96-45-7 \| ETHYLENE THIOUREA \| 2-Mercaptoimidazoline \| Imidazolidinethione \| N,N'-Ethylenethiourea \| Ethlenethiourea \| Sanceller 22 \| Soxinol 22 \| Robac 22 \| Mercazin I \| Warecure C \| Rhenogran ETU \| 2-Imidazoline-2-th
Specifications & Purity	≥97%
Shipped In	Normal

Associated Targets(Human)

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HepG2 (196354 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Lymphoblastoid cell (5959 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ERG Tbio Transcriptional regulator ERG (5589 Activities)

Discover Target: ERG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TAS2R38 Tchem Taste receptor type 2 member 38 (37 Activities)

Discover Target: TAS2R38

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hsf1 Heat shock factor protein 1 (5445 Activities)

Discover Target: Hsf1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488192171
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488192171
IUPAC Name	imidazolidine-2-thione
INCHI	InChI=1S/C3H6N2S/c6-3-4-1-2-5-3/h1-2H2,(H2,4,5,6)
InChi Key	PDQAZBWRQCGBEV-UHFFFAOYSA-N
Canonical SMILES	C1CNC(=S)N1
Isomeric SMILES	C1CNC(=S)N1
WGK Germany	2
RTECS	NI9625000
PubChem CID	2723650
UN Number	2811
Packing Group	I
Molecular Weight	102.16
Beilstein	106275
Reaxy-Rn	106275

Certificates

Certificate of Analysis(COA)

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16 results found

Lot Number	Certificate Type	Date	Item
I2201579	Certificate of Analysis	Jun 18, 2024	I109215
I2201580	Certificate of Analysis	Jun 18, 2024	I109215
I2201582	Certificate of Analysis	Jun 18, 2024	I109215
E2210096	Certificate of Analysis	Feb 22, 2024	I109215
E2210097	Certificate of Analysis	Feb 22, 2024	I109215
E2210099	Certificate of Analysis	Feb 22, 2024	I109215
E2210100	Certificate of Analysis	Feb 22, 2024	I109215
E2210101	Certificate of Analysis	Feb 22, 2024	I109215
C1822031	Certificate of Analysis	Aug 07, 2023	I109215
C2126062	Certificate of Analysis	Jan 11, 2023	I109215
C2126064	Certificate of Analysis	Jan 11, 2023	I109215
D23142328	Certificate of Analysis	Mar 18, 2022	I109215
C2420038	Certificate of Analysis	Nov 20, 2021	I109215
I2201578	Certificate of Analysis	Nov 20, 2021	I109215
I2201581	Certificate of Analysis	Nov 20, 2021	I109215
J2311059	Certificate of Analysis	Nov 20, 2021	I109215

Chemical and Physical Properties

Solubility	Slightly soluble in water; Degree of Solubility in water: 20 g/l 30 °C; Soluble in Methanol,Ethanol; Insoluble in Acetone,Chloroform,Ether,Benzene
Sensitivity	Moisture sensitive.
Flash Point(°F)	252°C
Flash Point(°C)	252°C
Melt Point(°C)	203-204°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Danger
Hazard Statements	H302:Harmful if swallowed H360D:May damage the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice.
WGK Germany	2
RTECS	NI9625000
Reaxy-Rn	106275
Class	6.1
Merck Index	3803

Citations of This Product

1. Zhu Yanshaozuo, Shen Xixun, Chen Qian, Xu Qunjie. (2023) Preparation and Corrosion Resistance of Silicate Phosphate Composite Passivation Film on Zinc Substrate by Simple Chemical Impregnation Method. JOM, (1-17). [PMID:]
2. Miao Tian, Jianbo Shuai, Brandon A. Bishop, Wei Zhang, Jimei Chen, Xiaohui Wang. (2023) Plant cellulose-based biomimetic artificial Small-Diameter vascular materials enabled by gradient Dual-Network entanglement. CHEMICAL ENGINEERING JOURNAL, 476 (146751). [PMID:19160488]
3. Jingming Wang, Zhiquan Yu, Yongfeng Wang, Yuanyao Chen, Lin Xiao, Yanjun Zong, Qiyuan Feng, Lianqi Peng, Huiping Zhang, Chunyan Liu. (2024) Ethylene thiourea exposure induces neurobehavioral toxicity in zebrafish by disrupting axon growth and neuromuscular junctions. Journal of Environmental Sciences, 137 (108). [PMID:37980000]
4. Feifei Xu, Jianghong Zhao, Jianlong Wang, Taotao Guan, Kaixi Li. (2022) Strong coordination ability of sulfur with cobalt for facilitating scale-up synthesis of Co9S8 encapsulated S, N co-doped carbon as a trifunctional electrocatalyst for oxygen reduction reaction, oxygen and hydrogen evolution reaction. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 608 (2623). [PMID:34794809]

References

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2. D Boers,L van Amelsvoort,C Colosio,E Corsini,S Fustinoni,L Campo,C Bosetti,C La Vecchia,T Vergieva,M Tarkowski,J Liesivuori,P Steerenberg,H van Loveren. (2008-12-02) Asthmatic symptoms after exposure to ethylenebisdithiocarbamates and other pesticides in the Europit field studies.. Human & experimental toxicology, 27 ((9)): (721-727). [PMID:19042955]
3. Ilaria Massarelli,Marcello Imbriani,Alessio Coi,Marilena Saraceno,Niccolò Carli,Anna Maria Bianucci. (2009-03-11) Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals.. European journal of medicinal chemistry, 44 ((9)): (3658-3664). [PMID:19272677]
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6. Tao Zhang,Yu Zuo Bai,Da Jia Wang,Hui Min Jia,Zheng Wei Yuan,Wei Lin Wang. (2009-04-24) Spatiotemporal pattern analysis of transcription factor 4 in the developing anorectum of the rat embryo with anorectal malformations.. International journal of colorectal disease, 24 ((9)): (1039-1047). [PMID:19387659]
7. Tao Zhang,Yu Zuo Bai,Dan Zhang,Shi Wei Zhang,Da Jia Wang,Hui Min Jia,Zheng Wei Yuan,Wei Lin Wang. (2009-07-29) Temporal and spatial expression of caudal-type homeobox gene-1 in the development of anorectal malformations in rat embryos.. Journal of pediatric surgery, 44 ((8)): (1568-1574). [PMID:19635307]
8. F Ahmadi,A A Alizadeh,F Bakhshandeh-Saraskanrood,B Jafari,M Khodadadian. (2009-09-22) Experimental and computational approach to the rational monitoring of hydrogen-bonding interaction of 2-Imidazolidinethione with DNA and guanine.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48 ((1)): (29-36). [PMID:19766693]
9. Kate Jones,Katan Patel,John Cocker,Ruth Bevan,Len Levy. (2009-11-17) Determination of ethylenethiourea in urine by liquid chromatography-atmospheric pressure chemical ionisation-mass spectrometry for monitoring background levels in the general population.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878 ((27)): (2563-2566). [PMID:19914152]
10. Hongmei Pan,Lishi Zhang. (2010-04-07) [Effects of ethylenethiourea on synthesis and secretion of thyroglobulin and iodide uptake of FRTL-5 cells].. Wei sheng yan jiu = Journal of hygiene research, 39 ((1)): (79-82). [PMID:20364596]
11. Renato Polimanti,Sara Piacentini,Maria Barone,Flavia Porreca,Maria Fuciarelli. (2010-04-10) Serum proteins and work habits in a group of farm-workers exposed to EBDCs.. Annals of human biology, 37 ((3)): (440-450). [PMID:20377494]
12. Zhang Dan,Zhang Zhi Bo,Zhang Tao,Zhang Shi Wei,Wang Da Jia,Zhang Shu Cheng,Yuan Zheng Wei,Wei-Lin Wang. (2010-04-14) Hoxd-13 expression in the development of hindgut in ethylenethiourea-exposed fetal rats.. Journal of pediatric surgery, 45 ((4)): (755-761). [PMID:20385283]
13. Cheol Lee,Gregory S Parks,Olivier Civelli. (2010-07-17) Anxiolytic effects of the MCH1R antagonist TPI 1361-17.. Journal of molecular neuroscience : MN, 43 ((2)): (132-137). [PMID:20635163]
14. Huimin Jia,Qingjiang Chen,Tao Zhang,Yuzuo Bai,Zhengwei Yuan,Weilin Wang. (2011-01-08) Wnt5a expression in the hindgut of fetal rats with chemically induced anorectal malformations--studies in the ETU rat model.. International journal of colorectal disease, 26 ((4)): (493-499). [PMID:21212964]
15. Aurore Bonnechère,Vincent Hanot,Joris Van Loco. (2011-06-17) A rapid and environmental friendly determination of the dithiocarbamate metabolites ethylenethiourea and propylenethiourea in fruit and vegetables by ultra high performance liquid chromatography tandem mass spectrometry.. Journal of chromatography. A, 1218 ((29)): (4627-4631). [PMID:21676400]
16. Yanlei Huang,Shan Zheng. (2011-07-19) The effect of vitamin A deficiency during pregnancy on anorectal malformations.. Journal of pediatric surgery, 46 ((7)): (1400-1405). [PMID:21763842]
17. . (2011-08-20) Ethylene thiourea.. Report on carcinogens : carcinogen profiles, 12 (191-194). [PMID:21852838]
18. Sidney Pereira Pinto Lemos,José Luiz Martins,Patrícia Veruska Ribeiro Barbosa Lemos,Silvio Romero Gonçalves e Silva,Fernando Leandro dos Santos,Valdemiro Amaro da Silva Júnior. (2012-03-31) Abnormalities of digestive tract innervation in rat fetus treated with ethylenethiourea.. Acta cirurgica brasileira, 27 ((3)): (244-250). [PMID:22460255]
19. Cristina Ripollés,Juan V Sancho,Francisco J López,Félix Hernández. (2012-05-15) Liquid chromatography coupled to tandem mass spectrometry for the residue determination of ethylenethiourea (ETU) and propylenethiourea (PTU) in water.. Journal of chromatography. A, 1243 (53-61). [PMID:22578799]
20. Subhendu Chandra,Joydeep Chowdhury,Manash Ghosh,G B Talapatra. (2012-10-25) Genesis of enhanced Raman bands in SERS spectra of 2-mercaptoimidazole: FTIR, Raman, DFT, and SERS.. The journal of physical chemistry. A, 116 ((45)): (10934-10947). [PMID:23092302]
21. Li Zhou,Xiaoliang Liu,Shu Kang,Fengzu Zhang,Canping Pan. (2013-02-16) A rapid determination method for ethylenethiourea in potato and cucumber by modified QuEChERS - high performance liquid chromatography-tandem mass spectrometry.. Food chemistry, 138 ((2-3)): (1355-1359). [PMID:23411254]
22. Eva Ekman,Margaretha Maxe,Margareta Littorin,Bo A G Jönsson,Christian H Lindh. (2013-07-31) High-throughput method for the analysis of ethylenethiourea with direct injection of hydrolysed urine using online on-column extraction liquid chromatography and triple quadrupole mass spectrometry.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 934 (53-59). [PMID:23896430]
23. Jin Zhang,Xiao-Bing Tang,Wei-Lin Wang,Zheng-Wei Yuan,Yu-Zuo Bai. (2015-06-23) Spatiotemporal expression of BMP7 in the development of anorectal malformations in fetal rats.. International journal of clinical and experimental pathology, 8 ((4)): (3727-3734). [PMID:26097554]
24. Huimin Jia,Qingjiang Chen,Tao Zhang,Yuzuo Bai,Zhengwei Yuan,Weilin Wang. (2010-10-05) The expression analysis of Notch-1 and Jagged-2 during the development of the hindgut in rat embryos with ethylenethiourea induced anorectal malformations.. The Journal of surgical research, 172 ((1)): (131-136). [PMID:20888582]
25. Qing Jiang Chen,Hui Min Jia,Zhi Xin Niu,Tao Zhang,Yu Zuo Bai,Zheng Wei Yuan,Wei Lin Wang. (2011-03-26) The development of satellite cells and their niche in striated muscle complex of anorectal malformations rat embryos.. The Journal of surgical research, 168 ((1)): (e71-e80). [PMID:21435657]
26. Xinyu Dong,Junwang Meng,Bo Yang,Yang Zhang,Jie Gan,Xi Shu,Jinian Shu. (2011-04-12) Experimental studies on ozonation of ethylenethiourea.. Journal of environmental sciences (China), 23 ((1)): (65-69). [PMID:21476342]
27. Reiko Kaneko,Nahoko Haneishi,Yoko Kawamura. (2012-03-28) [Improvement of 2-mercaptoimidazoline analysis in rubber products containing chlorine].. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 53 ((1)): (52-56). [PMID:22450670]
28. Csaba Vágvölgyi,Enikő Sajben-Nagy,Bettina Bóka,Mónika Vörös,Adrienn Berki,Andrea Palágyi,Judit Krisch,Biljana Skrbić,N Durišić-Mladenović,László Manczinger. (2012-11-13) Isolation and characterization of antagonistic Bacillus strains capable to degrade ethylenethiourea.. Current microbiology, 66 ((3)): (243-250). [PMID:23143288]
29. Xiantian Ren,Jie Mi,Huimin Jia,Hong Gao,Yuzuo Bai,Weilin Wang. (2015-05-31) Reduced Wnt3a expression correlates with poor development of the hindgut in rats with anorectal malformations.. Experimental and molecular pathology, 99 ((1)): (81-85). [PMID:26024594]
30. Zhu Yanshaozuo, Shen Xixun, Chen Qian, Xu Qunjie. (2023) Preparation and Corrosion Resistance of Silicate Phosphate Composite Passivation Film on Zinc Substrate by Simple Chemical Impregnation Method. JOM, (1-17). [PMID:]
31. Miao Tian, Jianbo Shuai, Brandon A. Bishop, Wei Zhang, Jimei Chen, Xiaohui Wang. (2023) Plant cellulose-based biomimetic artificial Small-Diameter vascular materials enabled by gradient Dual-Network entanglement. CHEMICAL ENGINEERING JOURNAL, 476 (146751). [PMID:19160488]
32. Jingming Wang, Zhiquan Yu, Yongfeng Wang, Yuanyao Chen, Lin Xiao, Yanjun Zong, Qiyuan Feng, Lianqi Peng, Huiping Zhang, Chunyan Liu. (2024) Ethylene thiourea exposure induces neurobehavioral toxicity in zebrafish by disrupting axon growth and neuromuscular junctions. Journal of Environmental Sciences, 137 (108). [PMID:37980000]
33. Feifei Xu, Jianghong Zhao, Jianlong Wang, Taotao Guan, Kaixi Li. (2022) Strong coordination ability of sulfur with cobalt for facilitating scale-up synthesis of Co9S8 encapsulated S, N co-doped carbon as a trifunctional electrocatalyst for oxygen reduction reaction, oxygen and hydrogen evolution reaction. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 608 (2623). [PMID:34794809]

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