2-Mercaptopyrimidine - >98.0%(HPLC), high purity , CAS No.1450-85-7

  • ≥98%(HPLC)
Item Number
M158441
Grouped product items
SKUSizeAvailabilityPrice Qty
M158441-5g
5g
In stock
$33.90
M158441-10g
10g
In stock
$50.90
M158441-25g
25g
In stock
$97.90
M158441-100g
100g
In stock
$352.90
M158441-250g
250g
In stock
$792.90

Basic Description

Synonyms2-Mercaptopyrimidine | 1450-85-7 | Pyrimidine-2-thiol | 2-Pyrimidinethiol | 2-Thiopyrimidine | Pyrimidine-2(1H)-thione | 2(1H)-Pyrimidinethione | 131242-36-9 | 1H-pyrimidine-2-thione | Pyrimidinethione | 2-Pyrimidinethione | thiopyrimidine | pyrimidine-2-thione | 1,2-dihydropyrimi
Specifications & Purity≥98%(HPLC)
Shipped InNormal
Product Description

2-Pyrimidinethiol has been used to study the highly selective palladium catalyzed kinetic resolutions of the racemic cyclic allylic carbonates and racemic acyclic allylic carbonates[1]. It has also been used to study the photodegradation of 2-pyrimidinethiol in aerated aqueous solution using zinc oxide.

Associated Targets(Human)

PRKAA2 Tchem AMP-activated protein kinase, alpha-2 subunit (1328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

J774.A1 (2436 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus anthracis (2936 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488191961
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488191961
IUPAC Name 1H-pyrimidine-2-thione
INCHI InChI=1S/C4H4N2S/c7-4-5-2-1-3-6-4/h1-3H,(H,5,6,7)
InChi Key HBCQSNAFLVXVAY-UHFFFAOYSA-N
Canonical SMILES C1=CNC(=S)N=C1
Isomeric SMILES C1=CNC(=S)N=C1
WGK Germany 3
PubChem CID 1550489
Molecular Weight 112.15
Beilstein 107105

Certificates

Certificate of Analysis(COA)

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15 results found

Lot NumberCertificate TypeDateItem
F2316598Certificate of AnalysisFeb 08, 2023 M158441
F2316789Certificate of AnalysisFeb 08, 2023 M158441
F2316793Certificate of AnalysisFeb 08, 2023 M158441
F2316799Certificate of AnalysisFeb 08, 2023 M158441
F2316800Certificate of AnalysisFeb 08, 2023 M158441
F2316802Certificate of AnalysisFeb 08, 2023 M158441
F2316805Certificate of AnalysisFeb 08, 2023 M158441
F2316808Certificate of AnalysisFeb 08, 2023 M158441
F2316815Certificate of AnalysisFeb 08, 2023 M158441
F2316824Certificate of AnalysisFeb 08, 2023 M158441
B2226052Certificate of AnalysisJan 03, 2022 M158441
B2226059Certificate of AnalysisJan 03, 2022 M158441
B2226070Certificate of AnalysisJan 03, 2022 M158441
B2226084Certificate of AnalysisJan 03, 2022 M158441
J2228119Certificate of AnalysisJan 03, 2022 M158441

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Chemical and Physical Properties

Melt Point(°C)230 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3

Related Documents

References

1. V Sood,H Kaur,R Sandhu.  (1989-01-01)  Effects of pyrimidine-2-thiol on the ovarian histology of Epilachna vigintioctopunctata (Fabr.) (Coleoptera: Coccinellidae)..  Folia morphologica,  37  ((4)): (402-406).  [PMID:2634600]
2. Hans-Joachim Gais,Thomas Jagusch,Nicole Spalthoff,Frank Gerhards,Michael Frank,Gerhard Raabe.  (2003-09-04)  Highly selective palladium catalyzed kinetic resolution and enantioselective substitution of racemic allylic carbonates with sulfur nucleophiles: asymmetric synthesis of allylic sulfides, allylic sulfones, and allylic alcohols..  Chemistry (Weinheim an der Bergstrasse, Germany),  ((17)): (4202-4221).  [PMID:12953206]
3. V Krishnakumar,R John Xavier.  (2005-07-02)  Molecular and vibrational structure of 2-mercapto pyrimidine and 2,4-diamino-6-hydroxy-5-nitroso pyrimidine: FT-IR, FT-Raman and quantum chemical calculations..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  63  ((2)): (454-463).  [PMID:15990356]
4. Denis Lima Guerra,Alane Azevedo Pinto,Janaína Azevedo de Souza,Claudio Airoldi,Rúbia Ribeiro Viana.  (2009-01-22)  Kinetic and thermodynamic uranyl (II) adsorption process into modified Na-Magadiite and Na-Kanemite..  Journal of hazardous materials,  166  ((2-3)): (1550-1555).  [PMID:19155125]
5. Zadkiel Alvarez,Kyungae Lee,Ernesto Abel-Santos.  (2010-10-06)  Testing nucleoside analogues as inhibitors of Bacillus anthracis spore germination in vitro and in macrophage cell culture..  Antimicrobial agents and chemotherapy,  54  ((12)): (5329-5336).  [PMID:20921305]
6. Jie Huang,Liming Zhang,Biao Chen,Nan Ji,Fenghua Chen,Yi Zhang,Zhijun Zhang.  (2010-10-12)  Nanocomposites of size-controlled gold nanoparticles and graphene oxide: formation and applications in SERS and catalysis..  Nanoscale,  ((12)): (2733-2738).  [PMID:20936236]
7. Barbara Cosimelli,Elda Severi,Ettore Novellino,Anna Cavaccini,Mauro Cataldi,Roberta Budriesi,Matteo Micucci,Alberto Chiarini,Pierfranco Ioan.  (2011-07-01)  Preliminary finding on a new calcium channel entry blocker chemotype: 5,6-diamino-4-hydroxy-2-mercaptopyrimidine derivatives..  Journal of medicinal chemistry,  54  ((15)): (5597-5601).  [PMID:21714522]
8. Homan Kang,Sinyoung Jeong,Yul Koh,Myeong Geun Cha,Jin-Kyoung Yang,San Kyeong,Jaehi Kim,Seon-Yeong Kwak,Hye-Jin Chang,Hyunmi Lee,Cheolhwan Jeong,Jong-Ho Kim,Bong-Hyun Jun,Yong-Kweon Kim,Dae Hong Jeong,Yoon-Sik Lee.  (2015-05-29)  Direct identification of on-bead peptides using surface-enhanced Raman spectroscopic barcoding system for high-throughput bioanalysis..  Scientific reports,  (10144-10144).  [PMID:26017924]
9. Mahboubeh Jamshidi,Mojgan Babaghasabha,Hamid R Shahsavari,S Masoud Nabavizadeh.  (2017-11-10)  The influence of thiolate ligands on the luminescence properties of cycloplatinated(ii) complexes..  Dalton transactions (Cambridge, England : 2003),  46  ((45)): (15919-15927).  [PMID:29119183]
10. Rebecca Portugal,Nana Shao,William B Whitman,Kylie D Allen,Robert H White.  (2019-02-05)  Identification and biosynthesis of 2-(1H-imidazol-5-yl) ethan-1-ol (histaminol) in methanogenic archaea..  Microbiology (Reading, England),  165  ((4)): (455-462).  [PMID:30714894]
11. Vivianne S Velozo-Sá,Luciano R Pereira,Aliny P Lima,Francyelli Mello-Andrade,Manuela R M Rezende,Rebeca M Goveia,Wanessa C Pires,Monize M Silva,Katia M Oliveira,Antonio G Ferreira,Javier Ellena,Victor M Deflon,Cesar Koppe Grisolia,Alzir A Batista,Elisângela P Silveira-Lacerda.  (2019-02-07)  In vitro cytotoxicity and in vivo zebrafish toxicity evaluation of Ru(ii)/2-mercaptopyrimidine complexes..  Dalton transactions (Cambridge, England : 2003),  48  ((18)): (6026-6039).  [PMID:30724926]
12. Peng Wang,Baishuang Yin,Huiling Dong,Yibo Zhang,Yangheng Zhang,Rixin Chen,Zukun Yang,Caoxing Huang,Qing Jiang.  (2020-09-26)  Coupling Biocompatible Au Nanoclusters and Cellulose Nanofibrils to Prepare the Antibacterial Nanocomposite Films..  Frontiers in bioengineering and biotechnology,  (986-986).  [PMID:32974314]
13. Josefa Angela García Calzón,Jesús Luis Muñiz Alvarez,Juan Miguel López Fonseca.  (2005-06-15)  Oxidation process induced by 2-mercaptopyrimidine at a mercury electrode..  Journal of colloid and interface science,  290  ((2)): (498-504).  [PMID:15953611]
14. Maria Carolina P Lima,Kaline Coutinho,Sylvio Canuto,Willian R Rocha.  (2006-06-02)  Reaction mechanism and tautomeric equilibrium of 2-mercaptopyrimidine in the gas phase and in aqueous solution: a combined Monte Carlo and quantum mechanics study..  The journal of physical chemistry. A,  110  ((22)): (7253-7261).  [PMID:16737277]
15. Morteza Montazerozohori,Bahador Karami,Mohammad Hossein Habibi,Jong-Ha Choi.  (2006-07-22)  Photodegradation kinetics of some thiols and thiones in aqueous suspension of zinc oxide..  Annali di chimica,  96  ((5-6)): (285-292).  [PMID:16856757]
16. Bahareh Khezri,Mohammad K Amini,Ali R Firooz.  (2008-03-04)  An optical chemical sensor for mercury ion based on 2-mercaptopyrimidine in PVC membrane..  Analytical and bioanalytical chemistry,  390  ((7)): (1943-1950).  [PMID:18311566]
17. Ganesh Patil,Rainer Rudolph,Christian Lange.  (2008-03-07)  In vitro-refolding of a single-chain Fv fragment in the presence of heteroaromatic thiols..  Journal of biotechnology,  134  ((3-4)): (218-221).  [PMID:18321603]

Solution Calculators