Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | Oxindole | 59-48-3 | Indolin-2-one | 2-Oxindole | 2-Indolinone | 1,3-Dihydro-2H-indol-2-one | 1,3-Dihydroindol-2-one | Oxindol | Indol-2(3H)-one | 2H-Indol-2-one, 1,3-dihydro- | 2-Oxoindoline | 2-Oxindoline | Indoline-2-one | MFCD00005711 | 2-OXOINDOLE | 2,3-dihydro-1H-indol-2-one | 1,3 |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
Associated Targets(Human)
PDK4 Tchem [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (0 Activities)
PDK2 Tchem [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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CMA1 Tchem Chymase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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CMA1 Tchem Chymase (726 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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PDK2 Tchem Pyruvate dehydrogenase kinase isoform 2 (894 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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PDK4 Tchem Pyruvate dehydrogenase kinase isoform 4 (177 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
Leishmania infantum (5912 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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RAW264.7 (28094 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Plutella xylostella (1838 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Spodoptera exigua (540 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 1,3-dihydroindol-2-one |
|---|---|
| INCHI | InChI=1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10) |
| InChi Key | JYGFTBXVXVMTGB-UHFFFAOYSA-N |
| Canonical SMILES | C1C2=CC=CC=C2NC1=O |
| Isomeric SMILES | C1C2=CC=CC=C2NC1=O |
| WGK Germany | 3 |
| RTECS | NM2080500 |
| PubChem CID | 321710 |
| Molecular Weight | 133.15 |
| Beilstein | 114692 |
| Reaxy-Rn | 114692 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Boil Point(°C) | 227°C/73mmHg |
|---|---|
| Melt Point(°C) | 123-128°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H302:Harmful if swallowed |
| Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
| WGK Germany | 3 |
| RTECS | NM2080500 |
| Reaxy-Rn | 114692 |
Related Documents
Citations of This Product
| 1. Yu-Tong Duan, Zhong-Xia Wang. (2023) Transition-Metal-Free α-C-Alkylation of Oxindoles with Alcohols. Asian Journal of Organic Chemistry, 12 (5): (e202300015). [PMID:] [10.1002/ajoc.202300015] |
| 2. Yuanyuan Zhu, Long Wu, Heng Yan, Zhicheng Lu, Wenmin Yin, Heyou Han. (2020) Enzyme induced molecularly imprinted polymer on SERS substrate for ultrasensitive detection of patulin. ANALYTICA CHIMICA ACTA, 1101 (111). [PMID:32029101] [10.1016/j.aca.2019.12.030] |
| 3. Li Yang, Wenxuan Wei, Yuanchi Ma, Yewei Xu, Guanjun Chang. (2020) Intermolecular channel expansion induced by cation-π interactions to enhance lithium storage in a crosslinked π-conjugated organic anode. JOURNAL OF POWER SOURCES, 449 (227551). [PMID:] [10.1016/j.jpowsour.2019.227551] |
| 4. Jiadi Sun, Wei Guo, Jian Ji, Zaijun Li, Xiao Yuan, Fuwei Pi, Yinzhi Zhang, Xiulan Sun. (2020) Removal of patulin in apple juice based on novel magnetic molecularly imprinted adsorbent Fe3O4@SiO2@CS-GO@MIP. LWT-FOOD SCIENCE AND TECHNOLOGY, 118 (108854). [PMID:] [10.1016/j.lwt.2019.108854] |
| 5. Chunle Wei, Jian Zhang, Jing Shi, Xiuhai Gan, Deyu Hu, Baoan Song. (2019) Synthesis, Antiviral Activity, and Induction of Plant Resistance of Indole Analogues Bearing Dithioacetal Moiety. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (50): (13882–13891). [PMID:31721582] [10.1021/acs.jafc.9b05357] |
| 6. Wu Long, Yan Heng, Li Guanghui, Xu Xin, Zhu Lin, Chen Xiaoqiang, Wang Jing. (2019) Surface-Imprinted Gold Nanoparticle-Based Surface-Enhanced Raman Scattering for Sensitive and Specific Detection of Patulin in Food Samples. Food Analytical Methods, 12 (7): (1648-1657). [PMID:] [10.1007/s12161-019-01498-4] |
| 7. Yanjuan Gao, Guoying Wang, Aijuan Zhou, Xiuping Yue, Yanqing Duan, Xin Kong, Xiao Zhang. (2019) Effect of nitrate on indole degradation characteristics and methanogenesis under mixed denitrification and methanogenesis culture. BIOCHEMICAL ENGINEERING JOURNAL, 145 (33). [PMID:] [10.1016/j.bej.2019.02.009] |
References
| 1. Yu-Tong Duan, Zhong-Xia Wang. (2023) Transition-Metal-Free α-C-Alkylation of Oxindoles with Alcohols. Asian Journal of Organic Chemistry, 12 (5): (e202300015). [PMID:] [10.1002/ajoc.202300015] |
| 2. Yuanyuan Zhu, Long Wu, Heng Yan, Zhicheng Lu, Wenmin Yin, Heyou Han. (2020) Enzyme induced molecularly imprinted polymer on SERS substrate for ultrasensitive detection of patulin. ANALYTICA CHIMICA ACTA, 1101 (111). [PMID:32029101] [10.1016/j.aca.2019.12.030] |
| 3. Li Yang, Wenxuan Wei, Yuanchi Ma, Yewei Xu, Guanjun Chang. (2020) Intermolecular channel expansion induced by cation-π interactions to enhance lithium storage in a crosslinked π-conjugated organic anode. JOURNAL OF POWER SOURCES, 449 (227551). [PMID:] [10.1016/j.jpowsour.2019.227551] |
| 4. Jiadi Sun, Wei Guo, Jian Ji, Zaijun Li, Xiao Yuan, Fuwei Pi, Yinzhi Zhang, Xiulan Sun. (2020) Removal of patulin in apple juice based on novel magnetic molecularly imprinted adsorbent Fe3O4@SiO2@CS-GO@MIP. LWT-FOOD SCIENCE AND TECHNOLOGY, 118 (108854). [PMID:] [10.1016/j.lwt.2019.108854] |
| 5. Chunle Wei, Jian Zhang, Jing Shi, Xiuhai Gan, Deyu Hu, Baoan Song. (2019) Synthesis, Antiviral Activity, and Induction of Plant Resistance of Indole Analogues Bearing Dithioacetal Moiety. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (50): (13882–13891). [PMID:31721582] [10.1021/acs.jafc.9b05357] |
| 6. Wu Long, Yan Heng, Li Guanghui, Xu Xin, Zhu Lin, Chen Xiaoqiang, Wang Jing. (2019) Surface-Imprinted Gold Nanoparticle-Based Surface-Enhanced Raman Scattering for Sensitive and Specific Detection of Patulin in Food Samples. Food Analytical Methods, 12 (7): (1648-1657). [PMID:] [10.1007/s12161-019-01498-4] |
| 7. Yanjuan Gao, Guoying Wang, Aijuan Zhou, Xiuping Yue, Yanqing Duan, Xin Kong, Xiao Zhang. (2019) Effect of nitrate on indole degradation characteristics and methanogenesis under mixed denitrification and methanogenesis culture. BIOCHEMICAL ENGINEERING JOURNAL, 145 (33). [PMID:] [10.1016/j.bej.2019.02.009] |