2-Phenylbenzimidazole - 98%, high purity , CAS No.716-79-0

  • ≥98%
Item Number
P101541
Grouped product items
SKUSizeAvailabilityPrice Qty
P101541-5g
5g
In stock
$22.90
P101541-25g
25g
In stock
$67.90
P101541-100g
100g
In stock
$171.90
P101541-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$773.90

Basic Description

SynonymsHMS3372F02 | NCGC00357026-01 | BDBM3789 | DTXCID2031033 | FT-0613322 | 2-phenyl benzimidazole | BRD-K90551865-001-05-1 | BCP27606 | Phenzidol | Phenizidole | 2-phenyl-1H-benzo[d]imidazole | 2-Phenylbenzimdazole | Q-101090 | 2-Phenyl-1H-benzoimidazole | BB
Specifications & Purity≥98%
Storage TempStore at 2-8°C
Shipped InWet ice
Note5g卖完停产,不再备货

Associated Targets(Human)

CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTH1R Tclin Parathyroid hormone/parathyroid hormone-related peptide receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RORC Tchem Nuclear receptor ROR-gamma (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FGFR1 Tclin Fibroblast growth factor receptor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HSF1 Tchem Heat shock factor protein 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KAT2A Tchem Histone acetyltransferase KAT2A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
POLI Tchem DNA polymerase iota (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDGFRB Tclin Platelet-derived growth factor receptor beta (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RAB9A Tbio Ras-related protein Rab-9A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GAA Tclin Lysosomal alpha-glucosidase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
BRCA1 Tchem Breast cancer type 1 susceptibility protein (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP19A1 Tclin Aromatase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GLP1R Tclin Glucagon-like peptide 1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NQO1 Tchem NAD(P)H dehydrogenase [quinone] 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NPC1 Tchem NPC intracellular cholesterol transporter 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP19A1 Tclin Cytochrome P450 19A1 (6099 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTH1R Tclin Parathyroid hormone receptor (47172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDGFRB Tclin Platelet-derived growth factor receptor beta (5195 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FGFR1 Tclin Fibroblast growth factor receptor 1 (9149 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BRCA1 Tchem Breast cancer type 1 susceptibility protein (15908 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NPC1 Tchem Niemann-Pick C1 protein (18985 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAB9A Tbio Ras-related protein Rab-9A (22488 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
microRNA 21 (64692 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cyp2b1 Cytochrome P450 2B1 (145 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Chlamydia pneumoniae (241 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rodentolepis nana (555 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus epidermidis (22802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhi (4293 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus niger (16508 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus cereus (7522 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania major (2877 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Heligmosomoides polygyrus (261 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Canis familiaris (36305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Felis catus (3858 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NIH3T3 (5395 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hsf1 Heat shock factor protein 1 (5445 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nqo1 NAD(P)H dehydrogenase [quinone] 1 (1058 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PYK Pyruvate kinase (6726 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-phenyl-1H-benzimidazole
INCHI InChI=1S/C13H10N2/c1-2-6-10(7-3-1)13-14-11-8-4-5-9-12(11)15-13/h1-9H,(H,14,15)
InChi Key DWYHDSLIWMUSOO-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2
Isomeric SMILES C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2
WGK Germany 3
RTECS DE0360000
PubChem CID 12855
Molecular Weight 194.23
Beilstein 23230
Reaxy-Rn 7087

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot NumberCertificate TypeDateItem
G2329716Certificate of AnalysisJun 30, 2023 P101541
G2329722Certificate of AnalysisJun 30, 2023 P101541
G2331070Certificate of AnalysisJun 30, 2023 P101541
G2331078Certificate of AnalysisJun 30, 2023 P101541
G2331079Certificate of AnalysisJun 30, 2023 P101541
G2331083Certificate of AnalysisJun 30, 2023 P101541
I2212184Certificate of AnalysisJul 30, 2022 P101541
I2212185Certificate of AnalysisJul 30, 2022 P101541
I2212186Certificate of AnalysisJul 30, 2022 P101541
I2212187Certificate of AnalysisJul 30, 2022 P101541
F2228435Certificate of AnalysisJun 06, 2022 P101541
F2228446Certificate of AnalysisJun 06, 2022 P101541
F2228504Certificate of AnalysisJun 06, 2022 P101541
F1819062Certificate of AnalysisApr 27, 2022 P101541
F1819061Certificate of AnalysisApr 27, 2022 P101541

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Chemical and Physical Properties

SolubilitySlightly soluble in water.Solubility in Methanol:almost transparency
Melt Point(°C)293-296 °C (lit.)

Safety and Hazards(GHS)

Pictogram(s) GHS05,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

H318:Causes serious eye damage

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS DE0360000
Reaxy-Rn 7087
Merck Index 7274

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Citations of This Product

1. Baoyu Wang, Mingrui Li, Songdang Zhang, Hongguo Wu, Yuhe Liao, Hu Li.  (2023)  Synergistic effect between Co single atoms and nanoparticles enables selective synthesis of bio-based benzimidazoles.  APPLIED CATALYSIS B-ENVIRONMENTAL,  327  (122454).  [PMID:] [10.1016/j.apcatb.2023.122454]

References

1. C Stevenson,R J Davies.  (1999-01-20)  Photosensitization of guanine-specific DNA damage by 2-phenylbenzimidazole and the sunscreen agent 2-phenylbenzimidazole-5-sulfonic acid..  Chemical research in toxicology,  12  ((1)): (38-45).  [PMID:9894016]
2. J Johnson Inbaraj,Piotr Bilski,Colin F Chignell.  (2002-03-09)  Photophysical and photochemical studies of 2-phenylbenzimidazole and UVB sunscreen 2-phenylbenzimidazole-5-sulfonic acid..  Photochemistry and photobiology,  75  ((2)): (107-116).  [PMID:11883597]
3. Charity N Mosley,Lei Wang,Stephanie Gilley,Shuguang Wang,Hongtao Yu.  (2007-07-10)  Light-induced cytotoxicity and genotoxicity of a sunscreen agent, 2-phenylbenzimidazole in Salmonella typhimurium TA 102 and HaCaT keratinocytes..  International journal of environmental research and public health,  ((2)): (126-131).  [PMID:17617675]
4. Mehrorang Ghaedi,Khodabakhsh Niknam,Ardeshir Shokrollahi,Ebrahim Niknam,Hamed Ghaedi,Mustafa Soylak.  (2008-03-04)  A solid phase extraction procedure for Fe3+, Cu2+ and Zn2+ ions on 2-phenyl-1H-benzo[d] imidazole loaded on Triton X-100-coated polyvinyl chloride..  Journal of hazardous materials,  158  ((1)): (131-136).  [PMID:18314265]
5. Michele Tonelli,Matteo Simone,Bruno Tasso,Federica Novelli,Vito Boido,Fabio Sparatore,Giuseppe Paglietti,Sabrina Pricl,Gabriele Giliberti,Sylvain Blois,Cristina Ibba,Giuseppina Sanna,Roberta Loddo,Paolo La Colla.  (2010-04-03)  Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives..  Bioorganic & medicinal chemistry,  18  ((8)): (2937-2953).  [PMID:20359898]
6. Lucksanee Wongkom,Ampa Jimtaisong.  (2016-10-26)  Novel biocomposite of carboxymethyl chitosan and pineapple peel carboxymethylcellulose as sunscreen carrier..  International journal of biological macromolecules,  95  (873-880).  [PMID:27777081]
7. Zi-Cheng Fu,Cheng Mi,Yan Sun,Zhi Yang,Quan-Qing Xu,Wen-Fu Fu.  (2019-05-19)  An Unexpected Iron (II)-Based Homogeneous Catalytic System for Highly Efficient CO2-to-CO Conversion under Visible-Light Irradiation..  Molecules (Basel, Switzerland),  24  ((10)):   [PMID:31100775]
8. Yukio Kubota,Seiji Tani,Junichi Nakamura.  (2003-08-09)  The interaction of 2-phenylbenzimidazole compounds with DNA: the influence of terminal substituents..  Nucleic acids research. Supplement (2001),  (2)  ((2)): (193-194).  [PMID:12903171]
9. Mark L Richards,Shirley Cruz Lio,Anjana Sinha,Homayon Banie,Richard J Thomas,Michael Major,Mark Tanji,Jagadish C Sircar.  (2006-05-02)  Substituted 2-phenyl-benzimidazole derivatives: novel compounds that suppress key markers of allergy..  European journal of medicinal chemistry,  41  ((8)): (950-969).  [PMID:16647159]
10. Shirley Cruz Lio,Jessica Johnson,Arka Chatterjee,Jeffrey W Ludwig,Diane Millis,Homayon Banie,Jagadish C Sircar,Anjana Sinha,Mark L Richards.  (2007-08-11)  Disruption of Golgi processing by 2-phenyl benzimidazole analogs blocks cell proliferation and slows tumor growth..  Cancer chemotherapy and pharmacology,  61  ((6)): (1045-1058).  [PMID:17690881]
11. Michele Tonelli,Vito Boido,Paolo La Colla,Roberta Loddo,Paola Posocco,Maria Silvia Paneni,Maurizio Fermeglia,Sabrina Pricl.  (2010-03-02)  Pharmacophore modeling, resistant mutant isolation, docking, and MM-PBSA analysis: Combined experimental/computer-assisted approaches to identify new inhibitors of the bovine viral diarrhea virus (BVDV)..  Bioorganic & medicinal chemistry,  18  ((6)): (2304-2316).  [PMID:20189812]
12. Caixia Xie,Xushuang Han,Jian Gong,Danyang Li,Chen Ma.  (2017-07-01)  One-pot strategy of copper-catalyzed synthesis of 1,2-disubstituted benzimidazoles..  Organic & biomolecular chemistry,  15  ((27)): (5811-5819).  [PMID:28660947]
13. Baoyu Wang, Mingrui Li, Songdang Zhang, Hongguo Wu, Yuhe Liao, Hu Li.  (2023)  Synergistic effect between Co single atoms and nanoparticles enables selective synthesis of bio-based benzimidazoles.  APPLIED CATALYSIS B-ENVIRONMENTAL,  327  (122454).  [PMID:] [10.1016/j.apcatb.2023.122454]

Solution Calculators