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2-Phenylbenzimidazole - 98%, high purity , CAS No.716-79-0

1 Citations

≥98%

CAS#: 716-79-0
Formula: C₁₃H₁₀N₂
Molecular Weight: 194.23
Beilstein Registry Number: 23230
EC Number: 211-939-2
MDL number: MFCD00005592
PubChem CID: 12855

Item Number

P101541

Grouped product items
SKU	Size	Availability	Price
P101541-5g	5g	In stock	$22.90
P101541-25g	25g	In stock	$67.90
P101541-100g	100g	In stock	$171.90
P101541-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$773.90

View related series

Benzimidazoles Five-Membered Heterocyclic Compounds

Basic Description

Synonyms	2-Phenylbenzimidazole \| 716-79-0 \| 2-phenyl-1H-benzo[d]imidazole \| 2-Phenyl-1H-benzimidazole \| Phenizidole \| Phenzidol \| Phenzidole \| Gainex \| 2-Phenylbenzimdazole \| 1H-Benzimidazole, 2-phenyl- \| 2-Phenyl-1H-benzoimidazole \| BENZIMIDAZOLE, 2-PHENYL- \| NSC 251956 \| 2-phenyl-1H-1,3-
Specifications & Purity	≥98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Note	5g卖完停产，不再备货

Associated Targets(Human)

CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTH1R Tclin Parathyroid hormone/parathyroid hormone-related peptide receptor (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FGFR1 Tclin Fibroblast growth factor receptor 1 (0 Activities)

Discover Target: FGFR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HSF1 Tchem Heat shock factor protein 1 (0 Activities)

Discover Target: HSF1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KAT2A Tchem Histone acetyltransferase KAT2A (0 Activities)

Discover Target: KAT2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

POLI Tchem DNA polymerase iota (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDGFRB Tclin Platelet-derived growth factor receptor beta (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RAB9A Tbio Ras-related protein Rab-9A (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GAA Tclin Lysosomal alpha-glucosidase (0 Activities)

Discover Target: GAA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BRCA1 Tchem Breast cancer type 1 susceptibility protein (0 Activities)

Discover Target: BRCA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP19A1 Tclin Aromatase (0 Activities)

Discover Target: CYP19A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ATAD5 Tbio ATPase family AAA domain-containing protein 5 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLP1R Tclin Glucagon-like peptide 1 receptor (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NQO1 Tchem NAD(P)H dehydrogenase [quinone] 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NPC1 Tchem NPC intracellular cholesterol transporter 1 (0 Activities)

Discover Target: NPC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP19A1 Tclin Cytochrome P450 19A1 (6099 Activities)

Discover Target: CYP19A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDGFRB Tclin Platelet-derived growth factor receptor beta (5195 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FGFR1 Tclin Fibroblast growth factor receptor 1 (9149 Activities)

Discover Target: FGFR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)

Discover Target: GAA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF7 (126967 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A549 (127892 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HepG2 (196354 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HeLa (62764 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLI Tchem DNA polymerase iota (116820 Activities)

Discover Target: POLI

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BRCA1 Tchem Breast cancer type 1 susceptibility protein (15908 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NPC1 Tchem Niemann-Pick C1 protein (18985 Activities)

Discover Target: NPC1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RAB9A Tbio Ras-related protein Rab-9A (22488 Activities)

Discover Target: RAB9A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

microRNA 21 (64692 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)

Discover Target: ATAD5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)

Discover Target: ampC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cyp2b1 Cytochrome P450 2B1 (145 Activities)

Discover Target: Cyp2b1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Chlamydia pneumoniae (241 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rodentolepis nana (555 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pseudomonas aeruginosa (123386 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus epidermidis (22802 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Salmonella typhi (4293 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Aspergillus niger (16508 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus subtilis (32866 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Enterococcus faecalis (29875 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus cereus (7522 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Candida albicans (78123 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Leishmania major (2877 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Heligmosomoides polygyrus (261 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Canis familiaris (36305 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Felis catus (3858 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NIH3T3 (5395 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GCN5 Histone acetyltransferase GCN5 (89 Activities)

Discover Target: GCN5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hsf1 Heat shock factor protein 1 (5445 Activities)

Discover Target: Hsf1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Luciferin 4-monooxygenase (66902 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nqo1 NAD(P)H dehydrogenase [quinone] 1 (1058 Activities)

Discover Target: Nqo1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PYK Pyruvate kinase (6726 Activities)

Discover Target: PYK

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NS1 Nonstructural protein 1 (33327 Activities)

Discover Target: NS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-phenyl-1H-benzimidazole
INCHI	InChI=1S/C13H10N2/c1-2-6-10(7-3-1)13-14-11-8-4-5-9-12(11)15-13/h1-9H,(H,14,15)
InChi Key	DWYHDSLIWMUSOO-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2
Isomeric SMILES	C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2
WGK Germany	3
RTECS	DE0360000
PubChem CID	12855
Molecular Weight	194.23
Beilstein	23230
Reaxy-Rn	7087

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

15 results found

Lot Number	Certificate Type	Date	Item
G2329716	Certificate of Analysis	Jun 30, 2023	P101541
G2329722	Certificate of Analysis	Jun 30, 2023	P101541
G2331070	Certificate of Analysis	Jun 30, 2023	P101541
G2331078	Certificate of Analysis	Jun 30, 2023	P101541
G2331079	Certificate of Analysis	Jun 30, 2023	P101541
G2331083	Certificate of Analysis	Jun 30, 2023	P101541
I2212184	Certificate of Analysis	Jul 30, 2022	P101541
I2212185	Certificate of Analysis	Jul 30, 2022	P101541
I2212186	Certificate of Analysis	Jul 30, 2022	P101541
I2212187	Certificate of Analysis	Jul 30, 2022	P101541
F2228435	Certificate of Analysis	Jun 06, 2022	P101541
F2228446	Certificate of Analysis	Jun 06, 2022	P101541
F2228504	Certificate of Analysis	Jun 06, 2022	P101541
F1819062	Certificate of Analysis	Apr 27, 2022	P101541
F1819061	Certificate of Analysis	Apr 27, 2022	P101541

Chemical and Physical Properties

Solubility	Slightly soluble in water.Solubility in Methanol:almost transparency
Melt Point(°C)	293-296 °C (lit.)

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H335:May cause respiratory irritation H302:Harmful if swallowed H318:Causes serious eye damage
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	DE0360000
Reaxy-Rn	7087
Merck Index	7274

Alternative Products

Citations of This Product

1. Baoyu Wang, Mingrui Li, Songdang Zhang, Hongguo Wu, Yuhe Liao, Hu Li. (2023) Synergistic effect between Co single atoms and nanoparticles enables selective synthesis of bio-based benzimidazoles. APPLIED CATALYSIS B-ENVIRONMENTAL, 327 (122454). [PMID:]

References

1. C Stevenson,R J Davies. (1999-01-20) Photosensitization of guanine-specific DNA damage by 2-phenylbenzimidazole and the sunscreen agent 2-phenylbenzimidazole-5-sulfonic acid.. Chemical research in toxicology, 12 ((1)): (38-45). [PMID:9894016]
2. J Johnson Inbaraj,Piotr Bilski,Colin F Chignell. (2002-03-09) Photophysical and photochemical studies of 2-phenylbenzimidazole and UVB sunscreen 2-phenylbenzimidazole-5-sulfonic acid.. Photochemistry and photobiology, 75 ((2)): (107-116). [PMID:11883597]
3. Charity N Mosley,Lei Wang,Stephanie Gilley,Shuguang Wang,Hongtao Yu. (2007-07-10) Light-induced cytotoxicity and genotoxicity of a sunscreen agent, 2-phenylbenzimidazole in Salmonella typhimurium TA 102 and HaCaT keratinocytes.. International journal of environmental research and public health, 4 ((2)): (126-131). [PMID:17617675]
4. Mehrorang Ghaedi,Khodabakhsh Niknam,Ardeshir Shokrollahi,Ebrahim Niknam,Hamed Ghaedi,Mustafa Soylak. (2008-03-04) A solid phase extraction procedure for Fe3+, Cu2+ and Zn2+ ions on 2-phenyl-1H-benzo[d] imidazole loaded on Triton X-100-coated polyvinyl chloride.. Journal of hazardous materials, 158 ((1)): (131-136). [PMID:18314265]
5. Michele Tonelli,Matteo Simone,Bruno Tasso,Federica Novelli,Vito Boido,Fabio Sparatore,Giuseppe Paglietti,Sabrina Pricl,Gabriele Giliberti,Sylvain Blois,Cristina Ibba,Giuseppina Sanna,Roberta Loddo,Paolo La Colla. (2010-04-03) Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives.. Bioorganic & medicinal chemistry, 18 ((8)): (2937-2953). [PMID:20359898]
6. Lucksanee Wongkom,Ampa Jimtaisong. (2016-10-26) Novel biocomposite of carboxymethyl chitosan and pineapple peel carboxymethylcellulose as sunscreen carrier.. International journal of biological macromolecules, 95 (873-880). [PMID:27777081]
7. Zi-Cheng Fu,Cheng Mi,Yan Sun,Zhi Yang,Quan-Qing Xu,Wen-Fu Fu. (2019-05-19) An Unexpected Iron (II)-Based Homogeneous Catalytic System for Highly Efficient CO2-to-CO Conversion under Visible-Light Irradiation.. Molecules (Basel, Switzerland), 24 ((10)): [PMID:31100775]
8. Yukio Kubota,Seiji Tani,Junichi Nakamura. (2003-08-09) The interaction of 2-phenylbenzimidazole compounds with DNA: the influence of terminal substituents.. Nucleic acids research. Supplement (2001), (2) ((2)): (193-194). [PMID:12903171]
9. Mark L Richards,Shirley Cruz Lio,Anjana Sinha,Homayon Banie,Richard J Thomas,Michael Major,Mark Tanji,Jagadish C Sircar. (2006-05-02) Substituted 2-phenyl-benzimidazole derivatives: novel compounds that suppress key markers of allergy.. European journal of medicinal chemistry, 41 ((8)): (950-969). [PMID:16647159]
10. Shirley Cruz Lio,Jessica Johnson,Arka Chatterjee,Jeffrey W Ludwig,Diane Millis,Homayon Banie,Jagadish C Sircar,Anjana Sinha,Mark L Richards. (2007-08-11) Disruption of Golgi processing by 2-phenyl benzimidazole analogs blocks cell proliferation and slows tumor growth.. Cancer chemotherapy and pharmacology, 61 ((6)): (1045-1058). [PMID:17690881]
11. Michele Tonelli,Vito Boido,Paolo La Colla,Roberta Loddo,Paola Posocco,Maria Silvia Paneni,Maurizio Fermeglia,Sabrina Pricl. (2010-03-02) Pharmacophore modeling, resistant mutant isolation, docking, and MM-PBSA analysis: Combined experimental/computer-assisted approaches to identify new inhibitors of the bovine viral diarrhea virus (BVDV).. Bioorganic & medicinal chemistry, 18 ((6)): (2304-2316). [PMID:20189812]
12. Caixia Xie,Xushuang Han,Jian Gong,Danyang Li,Chen Ma. (2017-07-01) One-pot strategy of copper-catalyzed synthesis of 1,2-disubstituted benzimidazoles.. Organic & biomolecular chemistry, 15 ((27)): (5811-5819). [PMID:28660947]
13. Baoyu Wang, Mingrui Li, Songdang Zhang, Hongguo Wu, Yuhe Liao, Hu Li. (2023) Synergistic effect between Co single atoms and nanoparticles enables selective synthesis of bio-based benzimidazoles. APPLIED CATALYSIS B-ENVIRONMENTAL, 327 (122454). [PMID:]

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