2-Phenylindole - 99%, high purity , CAS No.948-65-2

  • ≥99%
Item Number
P111467
Grouped product items
SKUSizeAvailabilityPrice Qty
P111467-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
P111467-25g
25g
In stock
$15.90
P111467-100g
100g
In stock
$25.90
P111467-250g
250g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$45.90
P111467-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$82.90

Basic Description

SynonymsEINECS 213-436-3 | MQD44HV3P1 | HMS2233J19 | NSC 15776 | SCHEMBL3835030 | SMR000526281 | DTXSID8061343 | 2-phenylindol | AB00876244-08 | alpha-Phenylindole | InChI=1/C14H11N/c1-2-6-11(7-3-1)14-10-12-8-4-5-9-13(12)15-14/h1-10,15 | SY032900 | 2-PHENYL-1H-IN
Specifications & Purity≥99%
Shipped InNormal
Product Description

2-Phenylindole is a reactant for preparation of organic light emitting diodes (OLEDs), anti inflammatory agents, antifungal and antibacterial agents and fluorescent probes. It is a reactant in difluorohydroxylation reactions and Mannich-type reactions.
A reactant in difluorohydroxylation reactions.


Application

Reactant for preparation of:

Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition

Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators

Organic light emitting diodes (OLEDs)

Anti inflammatory agents

Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors

Agents for cancer and malaria therapy

Antifungal and antibacterial agents

Fluorescent probes


Reactant in:

Difluorohydroxylation reactions†

Mannich-type reactions†

Associated Targets(Human)

CDK1 Tchem Cyclin-dependent kinase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ERG Tbio Transcriptional regulator ERG (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTH1R Tclin Parathyroid hormone/parathyroid hormone-related peptide receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RORC Tchem Nuclear receptor ROR-gamma (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FTL Tbio Ferritin light chain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
POLI Tchem DNA polymerase iota (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RAB9A Tbio Ras-related protein Rab-9A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP19A1 Tclin Aromatase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AKR1B1 Tclin Aldose reductase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TARDBP Tchem TAR DNA-binding protein 43 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NQO1 Tchem NAD(P)H dehydrogenase [quinone] 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NPC1 Tchem NPC intracellular cholesterol transporter 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP19A1 Tclin Cytochrome P450 19A1 (6099 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTH1R Tclin Parathyroid hormone receptor (47172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1B1 Tclin Aldose reductase (1404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-251 (51189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-87 MG (3946 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver (3974 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERG Tbio Transcriptional regulator ERG (5589 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NPC1 Tchem Niemann-Pick C1 protein (18985 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAB9A Tbio Ras-related protein Rab-9A (22488 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
microRNA 21 (64692 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CDK1 Tchem Cyclin-dependent kinase 1/cyclin B (899 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TARDBP Tchem TAR DNA-binding protein 43 (40113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus cereus (7522 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nqo1 NAD(P)H dehydrogenase [quinone] 1 (1058 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
norA Quinolone resistance protein norA (2171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fusarium culmorum (260 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Macrophomina phaseolina (474 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rhizoctonia solani (2251 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Globisporangium debaryanum (107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Peroxidase (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488181891
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181891
IUPAC Name 2-phenyl-1H-indole
INCHI InChI=1S/C14H11N/c1-2-6-11(7-3-1)14-10-12-8-4-5-9-13(12)15-14/h1-10,15H
InChi Key KLLLJCACIRKBDT-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)C2=CC3=CC=CC=C3N2
Isomeric SMILES C1=CC=C(C=C1)C2=CC3=CC=CC=C3N2
WGK Germany 3
RTECS NM1272500
PubChem CID 13698
Molecular Weight 193.24
Beilstein 20467
Reaxy-Rn 132356

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
G2215258Certificate of AnalysisJul 23, 2022 P111467
I2203415Certificate of AnalysisJun 17, 2022 P111467
I2203416Certificate of AnalysisJun 17, 2022 P111467
I2203417Certificate of AnalysisJun 17, 2022 P111467
I2203418Certificate of AnalysisJun 17, 2022 P111467
I2205122Certificate of AnalysisJun 17, 2022 P111467
G1805112Certificate of AnalysisMay 10, 2022 P111467
D2324733Certificate of AnalysisAug 28, 2021 P111467
H2125374Certificate of AnalysisAug 28, 2021 P111467

Chemical and Physical Properties

Boil Point(°C)250°C
Melt Point(°C)188-190°C

Safety and Hazards(GHS)

Pictogram(s) GHS05,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H335:May cause respiratory irritation

H413:May cause long lasting harmful effects to aquatic life

H318:Causes serious eye damage

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS NM1272500
Reaxy-Rn 132356

Related Documents

Citations of This Product

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2. Huikang Yang,Yingling Miao,Lipeng Chen,Zhuoran Li,Ruimeng Yang,Xiangdong Xu,Zhaosong Liu,Li-Ming Zhang,Xinqing Jiang.  (2020-01-12)  Redox-responsive nanoparticles from disulfide bond-linked poly-(N-ε-carbobenzyloxy-l-lysine)-grafted hyaluronan copolymers as theranostic nanoparticles for tumor-targeted MRI and chemotherapy..  International journal of biological macromolecules,  148  (483-492).  [PMID:31926232]
3. Yasong Hu,Congcong Zhan,Anduo Zhou,Shanfeng Zhang,Juying Chen,Xia Huang.  (2020-02-06)  Synthesis and characterization of L-tyrosine-conjugated quaternary ammonium salt chitosan and their cytocompatibility as a potential tissue engineering scaffold..  Journal of biomaterials science. Polymer edition,  31  ((7)): (833-848).  [PMID:32013748]
4. Kang Feng,Chunhua Ni,Liangmin Yu,Wenjun Zhou,Xia Li.  (2019-07-22)  Synthesis and antifouling evaluation of indole derivatives..  Ecotoxicology and environmental safety,  182  (109423-109423).  [PMID:31325810]

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23. Tao Gui,Yong-Kai Lin,Song-Wei Huan,Yu-Hang Li,Bao-Hua Wang,Jie Yang,Rong-He Gu,Qing Liu,Zhen-Yan Li,Sai-Mei Li,Yuan-Feng Chen,Huan-Tian Zhang,Zhen-Gang Zha.  (2019-03-20)  Elevated expression of ICAM-1 in synovium is associated with early inflammatory response for cartilage degeneration in type 2 diabetes mellitus..  Journal of cellular biochemistry,  120  ((8)): (13177-13186).  [PMID:30887556]
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30. Huikang Yang,Yingling Miao,Lipeng Chen,Zhuoran Li,Ruimeng Yang,Xiangdong Xu,Zhaosong Liu,Li-Ming Zhang,Xinqing Jiang.  (2020-01-12)  Redox-responsive nanoparticles from disulfide bond-linked poly-(N-ε-carbobenzyloxy-l-lysine)-grafted hyaluronan copolymers as theranostic nanoparticles for tumor-targeted MRI and chemotherapy..  International journal of biological macromolecules,  148  (483-492).  [PMID:31926232]
31. Syunsuke Yamamoto,Shin-Ichi Matsumoto,Hisao Shimizu,Hideki Hirabayashi.  (2020-01-26)  Quantitative application of flow cytometry for the analysis of circulating human T cells: A preclinical pharmacokinetic study..  Drug metabolism and pharmacokinetics,  35  ((2)): (207-213).  [PMID:31980378]
32. Alexis Cooper,Tamer Butto,Niklas Hammer,Somanath Jagannath,Desiree Lucia Fend-Guella,Junaid Akhtar,Konstantin Radyushkin,Florian Lesage,Jennifer Winter,Susanne Strand,Jochen Roeper,Ulrich Zechner,Susann Schweiger.  (2020-01-26)  Inhibition of histone deacetylation rescues phenotype in a mouse model of Birk-Barel intellectual disability syndrome..  Nature communications,  11  ((1)): (480-480).  [PMID:31980599]
33. Yasong Hu,Congcong Zhan,Anduo Zhou,Shanfeng Zhang,Juying Chen,Xia Huang.  (2020-02-06)  Synthesis and characterization of L-tyrosine-conjugated quaternary ammonium salt chitosan and their cytocompatibility as a potential tissue engineering scaffold..  Journal of biomaterials science. Polymer edition,  31  ((7)): (833-848).  [PMID:32013748]
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