Basic Description

Synonyms	22(R)-Hydroxycholesterol \| 17954-98-2 \| 22R-hydroxycholesterol \| 22beta-Hydroxycholesterol \| (22R)-22-Hydroxycholesterol \| cholest-5-en-3beta,22R-diol \| (22R)-Hydroxycholesterol \| (3beta,22R)-Cholest-5-ene-3,22-diol \| 22(r)hydroxycholesterol \| CHEMBL422904 \| (3S,8S,9S,10R,13
Specifications & Purity	≥99%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

RORC Tchem Nuclear receptor ROR-gamma (3 Activities)

Discover Target: RORC

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR1H2 Tchem Oxysterols receptor LXR-beta (0 Activities)

Discover Target: NR1H2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR1H3 Tchem Oxysterols receptor LXR-alpha (0 Activities)

Discover Target: NR1H3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR1H4 Tclin Bile acid receptor (0 Activities)

Discover Target: NR1H4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RXRA Tclin Retinoid X receptor alpha (3637 Activities)

Discover Target: RXRA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NPC1L1 Tclin Niemann-Pick C1-like protein 1 (346 Activities)

Discover Target: NPC1L1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR1H3 Tchem LXR-alpha (2891 Activities)

Discover Target: NR1H3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR1H2 Tchem LXR-beta (3841 Activities)

Discover Target: NR1H2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(3S,8S,9S,10R,13S,14S,17R)-17-[(2S,3R)-3-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
INCHI	InChI=1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25+,26-,27+/m0/s1
InChi Key	RZPAXNJLEKLXNO-GFKLAVDKSA-N
Canonical SMILES	CC(C)CCC(C(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)O
Isomeric SMILES	C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)[C@@H](CCC(C)C)O
WGK Germany	3
PubChem CID	167685
Molecular Weight	402.653

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot Number	Certificate Type	Date	Item
I2301368	Certificate of Analysis	Aug 16, 2023	C130204
I2301369	Certificate of Analysis	Aug 16, 2023	C130204
I2301370	Certificate of Analysis	Aug 16, 2023	C130204
I2301371	Certificate of Analysis	Aug 16, 2023	C130204
I2301372	Certificate of Analysis	Aug 16, 2023	C130204
I2301373	Certificate of Analysis	Aug 16, 2023	C130204
D1522065	Certificate of Analysis	Nov 17, 2022	C130204
F2329311	Certificate of Analysis	Nov 17, 2022	C130204

Safety and Hazards(GHS)

WGK Germany	3

Solution Calculators

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SKU	Size	Availability	Price
C130204-1mg	1mg	In stock	$84.90
C130204-5mg	5mg	In stock	$321.90
C130204-25mg	25mg	In stock	$1,444.90

22(R)-Hydroxycholesterol - >99%, high purity , CAS No.17954-98-2