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R465073-1mg

1mg

Available within 4-8 weeks(?)

$3,399.90

Basic Description

Synonyms	SECALCIFEROL \| 55721-11-4 \| Osteo D \| 24R,25-Dihydroxyvitamin D3 \| K-DR \| (24R)-Hydroxycalcidiol \| (24R)-24,25-dihydroxyvitamin D3 \| 24r,25-Dihydroxycholecalciferol \| 24(R),25-Dihydroxyvitamin D3 \| 24(R),25-Dihydroxycholecalciferol \| CHEBI:28818 \| 460029IUDA \| 24(r),25-(oh)2d3 \| 2
Specifications & Purity	≥98%, vitamin + pre-vitamin
Biochemical and Physiological Mechanisms	(24R)-24,25-Dihydroxyvitamin D3plays an essential role in calcium and phosphorus homeostasis. (24R)-24,25-Dihydroxyvitamin D3along with 1α,25(OH)2D3 stimulates bone metabolism.Cholecalciferol is an inactive form of vitamin D3 which undergoes var
Storage Temp	Protected from light,Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	(24R)-24,25-Dihydroxyvitamin D3or secalciferol is produced in kidney. It is the one of the most active form of vitamin D and an essential circulating vitamin D3metabolite.(24R)-24,25-Dihydroxyvitamin D3has been used to assess its function(s) compared with that of 1α,25(OH)2D3, during osteoblastic differentiation of primary human mesenchymal stem cells (hMSCs).

Associated Targets(Human)

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PMP22 Tbio Peripheral myelin protein 22 (699 Activities)

Discover Target: PMP22

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)

Discover Target: USP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Gc Vitamin D-binding protein (39 Activities)

Discover Target: Gc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(3R,6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-2,3-diol
INCHI	InChI=1S/C27H44O3/c1-18-8-12-22(28)17-21(18)11-10-20-7-6-16-27(5)23(13-14-24(20)27)19(2)9-15-25(29)26(3,4)30/h10-11,19,22-25,28-30H,1,6-9,12-17H2,2-5H3/b20-10+,21-11-/t19-,22+,23-,24+,25-,27-/m1/s1
InChi Key	FCKJYANJHNLEEP-XRWYNYHCSA-N
Canonical SMILES	CC(CCC(C(C)(C)O)O)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C
Isomeric SMILES	C[C@H](CC[C@H](C(C)(C)O)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C
WGK Germany	3
RTECS	VS2895000
PubChem CID	5283748
Molecular Weight	416.64
Beilstein	4567039

Certificates

Certificate of Analysis(COA)

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Lot Number	Certificate Type	Date	Item
J2314237	Certificate of Analysis	Sep 15, 2023	R465073

Chemical and Physical Properties

Sensitivity	Light sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H311:Toxic in contact with skin H330:Fatal if inhaled H372:Causes damage to organs through prolonged or repeated exposure H301+H311:Toxic if swallowed or in contact with skin
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	VS2895000

Alternative Products

References

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(24R)-24,25-Dihydroxyvitamin D₃ - ≥98% (vitamin + pre-vitamin), high purity , CAS No.55721-11-4