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3-[(3,4-dichlorophenyl)methylsulfanyl]thiophene-2-carboxylic acid , CAS No.D608879, Inhibitor of RTP Type G

PubChem CID: 2765033

Item Number

D608879

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SKU	Size	Availability	Price	Qty
D608879-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,400.90
D608879-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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RTP Type G Inhibitor

Basic Description

Synonyms	NXY \| GTPL8831 \| 3qcf \| DTXSID901173366 \| SMR000168583 \| 10G-330S \| 3-[(3,4-dichlorobenzyl)sulfanyl]-2-thiophenecarboxylic acid \| AKOS005069187 \| HMS2375J14 \| compound 1 [PMID: 21882820] \| 3-((3,4-Dichlorobenzyl)thio)thiophene-2-carboxylic acid \| MFCD0066
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of RTP Type G

Associated Targets(Human)

PTPRG Tchem Receptor-type tyrosine-protein phosphatase gamma (1 Activities)

Discover Target: PTPRG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTPRC Tchem Leukocyte common antigen (2317 Activities)

Discover Target: PTPRC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTPRG Tchem Receptor-type tyrosine-protein phosphatase gamma (63 Activities)

Discover Target: PTPRG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 (11476 Activities)

Discover Target: RAPGEF4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)

Discover Target: Ptpn1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FTL Ferritin light chain (43324 Activities)

Discover Target: FTL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NS1 Nonstructural protein 1 (33327 Activities)

Discover Target: NS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	3-[(3,4-dichlorophenyl)methylsulfanyl]thiophene-2-carboxylic acid
INCHI	InChI=1S/C12H8Cl2O2S2/c13-8-2-1-7(5-9(8)14)6-18-10-3-4-17-11(10)12(15)16/h1-5H,6H2,(H,15,16)
InChi Key	UCHDVTOVFHVWOS-UHFFFAOYSA-N
Canonical SMILES	OC(=O)c1sccc1SCc1ccc(c(c1)Cl)Cl
Isomeric SMILES	C1=CC(=C(C=C1CSC2=C(SC=C2)C(=O)O)Cl)Cl
PubChem CID	2765033

PubChem CID

2765033

ChEMBL Ligand

CHEMBL1403981

RCSB PDB Ligand

NXY

References

1. Sheriff S, Beno BR, Zhai W, Kostich WA, McDonnell PA, Kish K, Goldfarb V, Gao M, Kiefer SE, Yanchunas J et al.. (2011) Small molecule receptor protein tyrosine phosphatase γ (RPTPγ) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop.. J Med Chem, 54 (19): (6548-62). [PMID:21882820] [10.1021/op500134e]

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3-[(3,4-dichlorophenyl)methylsulfanyl]thiophene-2-carboxylic acid , CAS No.D608879, Inhibitor of RTP Type G

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

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