3,3′-Diindolylmethane - ≥98%(HPLC), high purity , CAS No.1968-05-4, Allosteric modulator of GPR84

Item Number

D129118

• Synonyms: NCGC00095348-01 | 3,3'-Diindolymethane | HY-15758 | SB16901 | bis-1H-indol-3-ylmethane | NCGC00095348-03 | SY038972 | SMR001828114 | NCGC00095348-06 | Bio1_000614 | 3,3'-Diindolylmethane | 3,3'-Di-indolylmethane | 3,3-Diindolylmethane | HMS1361A12 | Bio1_
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol.It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced a
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: ALLOSTERIC MODULATOR
• Mechanism of action: Allosteric modulator of GPR84
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

3,3'-Diindolylmethane is an anticancer and antineoplastic agent. 3,3'-Diindolylmethane induces apoptosis in human cancer cells. 3,3'-Diindolylmethane is also an activator of CYP (cytochrome P450) and Chk2 (checkpoint kinase 2) as well as a partial agonist of aryl hydrocarbon receptor (Ah Receptor). The compound is a dimer of indole-3-carbinol.
An antineoplastic agent that activates Chk 2 and cytochrome p450