Basic Description

Synonyms	DTXSID5026205 \| DTXCID006205 \| Tox21_200704 \| AH0CU8672K \| MFCD03844725 \| CS-0127963 \| 1,2,3-Trichloro-5-nitrobenzene, 96% \| 2-amino-8,9-dihydronaphtho[1,2-d]thiazole \| NCGC00091289-02 \| NCGC00258258-01 \| 3,4,5-Trichloro Nitro Benzene \| T1580 \| NSC523881
Specifications & Purity	≥96%
Shipped In	Normal
Product Description	1,2,3-Trichloro-5-nitrobenzene is a chloronitrobenzene (CNB) compound. In vitro nephrotoxic potential of 1,2,3-trichloro-5-nitrobenzene in animal models and human kidney cells has been investigated. Toxicological study of 1,2,3-trichloro-5-nitrobenzene has been reported.2

Associated Targets(Human)

ALDH1A1 Tchem Retinal dehydrogenase 1 (0 Activities)

Discover Target: ALDH1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)

Discover Target: NFE2L2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CXCL8 Tchem Interleukin-8 (0 Activities)

Discover Target: CXCL8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CXCL8 Tchem Interleukin-8 (642 Activities)

Discover Target: CXCL8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488186490
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488186490
IUPAC Name	1,2,3-trichloro-5-nitrobenzene
INCHI	InChI=1S/C6H2Cl3NO2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H
InChi Key	HHLCSFGOTLUREE-UHFFFAOYSA-N
Canonical SMILES	C1=C(C=C(C(=C1Cl)Cl)Cl)[N+](=O)[O-]
Isomeric SMILES	C1=C(C=C(C(=C1Cl)Cl)Cl)[N+](=O)[O-]
WGK Germany	3
PubChem CID	88365
UN Number	2811
Packing Group	I
Molecular Weight	226.44
Beilstein	5(2)187
Reaxy-Rn	2505480

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number	Certificate Type	Date	Item
K1907152	Certificate of Analysis	Aug 11, 2023	T162602

Chemical and Physical Properties

Melt Point(°C)	68-71°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	2505480
Class	6.1

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

SKU	Size	Availability	Price
T162602-5g	5g	In stock	$26.90
T162602-25g	25g	In stock	$117.90
T162602-100g	100g	In stock	$424.90

3,4,5-Trichloronitrobenzene - >96.0%, high purity , CAS No.20098-48-0