3,4,5-Trimethoxybenzoic acid - 99%, high purity , CAS No.118-41-2

  • ≥99%
Item Number
T106593
Grouped product items
SKUSizeAvailabilityPrice Qty
T106593-25g
25g
In stock
$14.90
T106593-100g
100g
In stock
$51.90
T106593-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$85.90

Basic Description

SynonymsKBio3_001180 | TRIMETHOPRIM IMPURITY J [EP IMPURITY] | Trimethylgallic acid | CHEBI:454991 | EC 204-248-2 | H5A | Eudesmic Acid; 3,4,5-Trimethoxybenzoic acid; Trimethylgallic acid; 5-methoxy-veratric acid; Gallic acid trimethyl ether | Q-200337 | SpecPlus
Specifications & Purity≥99%
Shipped InNormal
Note250g卖完停产,不再备货

Associated Targets(Human)

CBX1 Tbio Chromobox protein homolog 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GMNN Tbio Geminin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TLR2 Tchem Toll-like receptor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TAS2R39 Tchem Taste receptor type 2 member 39 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR0B1 Tbio Nuclear receptor subfamily 0 group B member 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TLR2 Tchem Toll-like receptor 2 (975 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR0B1 Tbio Nuclear receptor subfamily 0 group B member 1 (493 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Nannizzia gypsea (2039 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus flavus (8875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus niger (16508 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus fumigatus (16427 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida tropicalis (8381 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichophyton rubrum (3646 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Epidermophyton floccosum (561 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichophyton mentagrophytes (4846 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Heterodera zeae (651 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488180761
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180761
IUPAC Name 3,4,5-trimethoxybenzoic acid
INCHI InChI=1S/C10H12O5/c1-13-7-4-6(10(11)12)5-8(14-2)9(7)15-3/h4-5H,1-3H3,(H,11,12)
InChi Key SJSOFNCYXJUNBT-UHFFFAOYSA-N
Canonical SMILES COC1=CC(=CC(=C1OC)OC)C(=O)O
Isomeric SMILES COC1=CC(=CC(=C1OC)OC)C(=O)O
WGK Germany 1
PubChem CID 8357
Molecular Weight 212.2
Beilstein 884655
Reaxy-Rn 884655

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot NumberCertificate TypeDateItem
G2430040Certificate of AnalysisMay 07, 2024 T106593
G2430077Certificate of AnalysisMay 07, 2024 T106593
B2210086Certificate of AnalysisJan 11, 2022 T106593
B2210093Certificate of AnalysisJan 11, 2022 T106593
B2210094Certificate of AnalysisJan 11, 2022 T106593
B2210095Certificate of AnalysisJan 11, 2022 T106593
E2304288Certificate of AnalysisJan 11, 2022 T106593

Chemical and Physical Properties

SolubilitySoluble in ethanol, ethyl ether and chloroform. Slightly soluble in water.
Boil Point(°C)225-227°C
Melt Point(°C)171-172°C

Safety and Hazards(GHS)

WGK Germany 1
Reaxy-Rn 884655

Related Documents

References

1. M Tasaki,Y Kamagata,K Nakamura,E Mikami.  (1992-01-01)  Utilization of methoxylated benzoates and formation of intermediates by Desulfotomaculum thermobenzoicum in the presence or absence of sulfate..  Archives of microbiology,  157  ((3)): (209-212).  [PMID:1510551]
2. R Glinka,H Mikołajewska,A Szadowska,M Kiełek.  (1985-01-01)  [Synthesis and the study of the effect of new 3,4,5-trimethoxybenzoic acid derivatives on the central nervous system]..  Acta poloniae pharmaceutica,  42  ((2)): (117-122).  [PMID:4083052]
3. H Naviasky.  (1984-04-01)  Quantitative analysis of trimethobenzamide hydrochloride by ion-pair column chromatography and semiquantitative analysis of 3,4,5-trimethoxybenzoic acid by thin-layer chromatography..  Journal of pharmaceutical sciences,  73  ((4)): (542-545).  [PMID:6726641]
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5. H Tateno,Y Kamiguchi,M Shimada,S Sugawara,K Mikamo.  (1995-03-01)  Induction of aneuploidy in Chinese hamster oocytes following in vivo treatments with trimethoxybenzoic compounds and their analogues..  Mutation research,  327  ((1-2)): (237-246).  [PMID:7870093]
6. Y Mimaki,M Kuroda,A Kameyama,Y Sashida,T Hirano,K Oka,K Koike,T Nikaido.  (1996-06-01)  A new cytotoxic cholestane bisdesmoside from Ornithogalum saundersiae bulbs..  Bioscience, biotechnology, and biochemistry,  60  ((6)): (1049-1050).  [PMID:8695908]
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8. Hong-Fang Ji,Hong-Yu Zhang,Liang Shen.  (2006-05-23)  Proton dissociation is important to understanding structure-activity relationships of gallic acid antioxidants..  Bioorganic & medicinal chemistry letters,  16  ((15)): (4095-4098).  [PMID:16713262]
9. P C Leal,A Mascarello,M Derita,F Zuljan,R J Nunes,S Zacchino,R A Yunes.  (2009-02-24)  Relation between lipophilicity of alkyl gallates and antifungal activity against yeasts and filamentous fungi..  Bioorganic & medicinal chemistry letters,  19  ((6)): (1793-1796).  [PMID:19232493]
10. Vikas Srivastava,Arvind Singh Negi,P V Ajayakumar,Shamshad A Khan,Suchitra Banerjee.  (2012-01-17)  Atropa belladonna hairy roots: orchestration of concurrent oxidation and reduction reactions for biotransformation of carbonyl compounds..  Applied biochemistry and biotechnology,  166  ((6)): (1401-1408).  [PMID:22246731]
11. Tian-Shan Wang,You-Ping Luo,Jing Wang,Meng-Xiong He,Ming-Guo Zhong,Ying Li,Xiao-Ping Song.  (2013-12-21)  (+)-rumphiin and polyalthurea, new compounds from the stems of Polyalthia rumphii..  Natural product communications,  ((10)): (1427-1429).  [PMID:24354193]
12. Mohamed A Farag,Dalia A Al-Mahdy,Riham Salah El Dine,Sherifa Fahmy,Aymen Yassin,Andrea Porzel,Wolfgang Brandt.  (2015-06-18)  Structure-Activity Relationships of Antimicrobial Gallic Acid Derivatives from Pomegranate and Acacia Fruit Extracts against Potato Bacterial Wilt Pathogen..  Chemistry & biodiversity,  12  ((6)): (955-962).  [PMID:26080741]
13. S Kleis-San Francisco,A W Schuetz.  (1987-10-01)  Sources of calcium and the involvement of calmodulin during steroidogenesis and oocyte maturation in follicles of Rana pipiens..  The Journal of experimental zoology,  244  ((1)): (133-143).  [PMID:2447220]
14. E Pogonowska-Wala.  (1981-10-01)  Craviten hydrolysis in plasma in vitro..  Polish journal of pharmacology and pharmacy,  33  ((3)): (365-371).  [PMID:7322949]
15. E N Schachter,E Zuskin,N Rienzi,S Goswami,S Maayani.  (1998-10-23)  Pharmacologic characterization of latex extracts by isolated guinea pig tracheal tissue..  Respiration; international review of thoracic diseases,  65  ((5)): (393-400).  [PMID:9782223]
16. Yan-Jun Hu,Hua-Guang Yu,Jia-Xin Dong,Xi Yang,Yi Liu.  (2006-05-09)  Spectroscopic studies on the interaction between 3,4,5-trimethoxybenzoic acid and bovine serum albumin..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  65  ((3-4)): (988-992).  [PMID:16679051]
17. Michael C Dodd,Ching-Hua Huang.  (2006-12-19)  Aqueous chlorination of the antibacterial agent trimethoprim: reaction kinetics and pathways..  Water research,  41  ((3)): (647-655).  [PMID:17173950]
18. Mao-Hsien Wang,Rui-Feng Lin,Hsiang-Chien Tseng,Hung-Sheng Soung,Kuo-Chi Chang,Cheng-Chia Tsai.  (2015-02-11)  (-) Epigallocatechin-3-gallate attenuates reserpine-induced orofacial dyskinesia and oxidative stress in rat striatum..  Pharmacology, biochemistry, and behavior,  131  (71-76).  [PMID:25668129]

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