3,4-Dichloronitrobenzene - >97.0%(GC), high purity , CAS No.99-54-7

  • ≥97%(GC)
Item Number
D155955
Grouped product items
SKUSizeAvailabilityPrice Qty
D155955-100g
100g
In stock
$25.90
D155955-250g
250g
In stock
$49.90
D155955-500g
500g
In stock
$76.90

Basic Description

SynonymsIJT74JI7FS | DTXCID504999 | WLN: WNR CG DG | BRN 1818163 | 3,4-Dichlornitrobenzen | A19495 | AI3-03268 | D0388 | InChI=1/C6H3Cl2NO2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3 | DCNB | DTXSID8024999 | NSC99806 | NSC-99806 | SCHEMBL85918 | AKOS005157643 | 3,4-Dichlorn
Specifications & Purity≥97%(GC)
Shipped InNormal
Product Description

application:

1,2-Dichloro-4-nitrobenzene is an intermediate in the synthesis of agrochemicals. Studies have been conducted to use 1,2-Dichloro-4-nitrobenzene as an organic intermediate for the synthetic preparation of ciprofloxacin.

Associated Targets(Human)

HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GSTM2 Tchem Glutathione S-transferase Mu 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GSTM2 Tchem Glutathione S-transferase Mu 2 (77 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488180434
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180434
IUPAC Name 1,2-dichloro-4-nitrobenzene
INCHI InChI=1S/C6H3Cl2NO2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H
InChi Key NTBYINQTYWZXLH-UHFFFAOYSA-N
Canonical SMILES C1=CC(=C(C=C1[N+](=O)[O-])Cl)Cl
Isomeric SMILES C1=CC(=C(C=C1[N+](=O)[O-])Cl)Cl
WGK Germany 3
RTECS CZ5250000
PubChem CID 7443
UN Number 2811
Packing Group I
Molecular Weight 192
Reaxy-Rn 1818163

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot NumberCertificate TypeDateItem
H2003064Certificate of AnalysisJun 13, 2024 D155955
C2002017Certificate of AnalysisDec 15, 2023 D155955
F2303227Certificate of AnalysisMay 20, 2023 D155955
F2303228Certificate of AnalysisMay 20, 2023 D155955
F2303229Certificate of AnalysisMay 20, 2023 D155955
L2216723Certificate of AnalysisNov 23, 2022 D155955
L2216749Certificate of AnalysisNov 23, 2022 D155955
L2216756Certificate of AnalysisNov 23, 2022 D155955
L2216760Certificate of AnalysisNov 23, 2022 D155955
L2216761Certificate of AnalysisNov 23, 2022 D155955
F2202183Certificate of AnalysisMay 19, 2022 D155955
F2202198Certificate of AnalysisMay 19, 2022 D155955
F2204429Certificate of AnalysisMay 19, 2022 D155955

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Chemical and Physical Properties

Flash Point(°F)253°F
Flash Point(°C)123 °C
Boil Point(°C)255°C
Melt Point(°C)38°C-43°C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS09,   GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H411:Toxic to aquatic life with long lasting effects

H302:Harmful if swallowed

H317:May cause an allergic skin reaction

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 3
RTECS CZ5250000
Reaxy-Rn 1818163
Class 9

Related Documents

Citations of This Product

1. Cholnam Ri, Fengxiang Li, Hyokchol Mun, Linan Liu, Jingchun Tang.  (2023)  Ball-milled Fe0/FeS2 enhanced interaction of Shewanella oneidensis MR-1 with anaerobic microbial community: Impact on 2,4-dichloronitrobenzene reduction and methane yield.  CHEMICAL ENGINEERING JOURNAL,  452  (139086).  [PMID:] [10.1016/j.cej.2022.139086]
2. Simeng Chu, Yujie Lu, Wenjuan Liu, Xiaoyao Ma, Jiamin Peng, Xiaoying Wang, Min Jiang, Gang Bai.  (2022)  Ursolic acid alleviates tetrandrine-induced hepatotoxicity by competitively binding to the substrate-binding site of glutathione S-transferases.  PHYTOMEDICINE,  104  (154325).  [PMID:35820303] [10.1016/j.phymed.2022.154325]
3. Zhou Lan, Yangcheng Lu.  (2022)  How the substrate affects amination reaction kinetics of nitrochlorobenzene.  Reaction Chemistry & Engineering,  (4): (833-838).  [PMID:] [10.1039/D1RE00534K]
4. Binbin Feng, Qionghao Xu, Xiaoxue Wu, Chunlin Ye, Yanghe Fu, De-Li Chen, Fumin Zhang, Weidong Zhu.  (2021)  MOF-derived N-doped carbon composites embedded with Fe/Fe3C nanoparticles as highly chemoselective and stable catalysts for catalytic transfer hydrogenation of nitroarenes.  APPLIED SURFACE SCIENCE,  557  (149837).  [PMID:] [10.1016/j.apsusc.2021.149837]
5. Lan Zhou, Lu Yangcheng.  (2021)  Continuous nitration of o-dichlorobenzene in micropacked-bed reactor: process design and modelling.  Journal of Flow Chemistry,  11  (2): (171-179).  [PMID:] [10.1007/s41981-020-00132-3]

References

1. Cholnam Ri, Fengxiang Li, Hyokchol Mun, Linan Liu, Jingchun Tang.  (2023)  Ball-milled Fe0/FeS2 enhanced interaction of Shewanella oneidensis MR-1 with anaerobic microbial community: Impact on 2,4-dichloronitrobenzene reduction and methane yield.  CHEMICAL ENGINEERING JOURNAL,  452  (139086).  [PMID:] [10.1016/j.cej.2022.139086]
2. Simeng Chu, Yujie Lu, Wenjuan Liu, Xiaoyao Ma, Jiamin Peng, Xiaoying Wang, Min Jiang, Gang Bai.  (2022)  Ursolic acid alleviates tetrandrine-induced hepatotoxicity by competitively binding to the substrate-binding site of glutathione S-transferases.  PHYTOMEDICINE,  104  (154325).  [PMID:35820303] [10.1016/j.phymed.2022.154325]
3. Zhou Lan, Yangcheng Lu.  (2022)  How the substrate affects amination reaction kinetics of nitrochlorobenzene.  Reaction Chemistry & Engineering,  (4): (833-838).  [PMID:] [10.1039/D1RE00534K]
4. Binbin Feng, Qionghao Xu, Xiaoxue Wu, Chunlin Ye, Yanghe Fu, De-Li Chen, Fumin Zhang, Weidong Zhu.  (2021)  MOF-derived N-doped carbon composites embedded with Fe/Fe3C nanoparticles as highly chemoselective and stable catalysts for catalytic transfer hydrogenation of nitroarenes.  APPLIED SURFACE SCIENCE,  557  (149837).  [PMID:] [10.1016/j.apsusc.2021.149837]
5. Lan Zhou, Lu Yangcheng.  (2021)  Continuous nitration of o-dichlorobenzene in micropacked-bed reactor: process design and modelling.  Journal of Flow Chemistry,  11  (2): (171-179).  [PMID:] [10.1007/s41981-020-00132-3]

Solution Calculators