3,4-Dihydro-2H-pyran - 98%, high purity , CAS No.110-87-2

  • ≥98%
Item Number
D106433
Grouped product items
SKUSizeAvailabilityPrice Qty
D106433-25ml
25ml
In stock
$13.90
D106433-100ml
100ml
In stock
$24.90
D106433-500ml
500ml
In stock
$111.90

Basic Description

Synonyms2,4-dihydropyran | AKOS000121126 | 3,4 - Dihydro-2H-pyran | 3,4-dihydropyrane | 2,3dihydropyran | 2,3-dihydro-pyran | 2H-3,4-Dihydropyran | 3,4-dihydro-[2H]-pyran | UN2376 | UNII-T6V9N71IHX | 3,4-Dihydro(2H)pyran | 4,5-dihydropyran | dihyrdopyran | 3,4-Di
Specifications & Purity≥98%
Shipped InNormal
Product Description

Widely used OH-protecting reagent.

Associated Targets(non-human)

Microsporum canis (872 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Epidermophyton floccosum (561 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488180683
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180683
IUPAC Name 3,4-dihydro-2H-pyran
INCHI InChI=1S/C5H8O/c1-2-4-6-5-3-1/h2,4H,1,3,5H2
InChi Key BUDQDWGNQVEFAC-UHFFFAOYSA-N
Canonical SMILES C1CC=COC1
Isomeric SMILES C1CC=COC1
WGK Germany 3
PubChem CID 8080
UN Number 2376
Packing Group II
Molecular Weight 84.12
Beilstein 103493
Reaxy-Rn 103493

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot NumberCertificate TypeDateItem
C23311610Certificate of AnalysisFeb 19, 2022 D106433
C23311611Certificate of AnalysisFeb 19, 2022 D106433
E2231272Certificate of AnalysisFeb 19, 2022 D106433
E2231274Certificate of AnalysisFeb 19, 2022 D106433
E2231280Certificate of AnalysisFeb 19, 2022 D106433
E2231285Certificate of AnalysisFeb 19, 2022 D106433
I2308140Certificate of AnalysisFeb 19, 2022 D106433

Chemical and Physical Properties

SolubilityMiscible with water and chloroform.
SensitivityHeat sensitive
Refractive Index1.44
Flash Point(°F)3.2 °F
Flash Point(°C)-9℃
Boil Point(°C)86°C
Melt Point(°C)-70°C

Safety and Hazards(GHS)

Pictogram(s) GHS07,   GHS02
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H225:Highly Flammable liquid and vapor

H317:May cause an allergic skin reaction

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

WGK Germany 3
Reaxy-Rn 103493
Class 3

Related Documents

Citations of This Product

1. Xiaojie Duan,Zhengqiang Jiang,Yu Liu,Qiaojuan Yan,Man Xiang,Shaoqing Yang.  (2019-05-28)  High-level expression of codon-optimized Thielavia terrestris cutinase suitable for ester biosynthesis and biodegradation..  International journal of biological macromolecules,  135  (768-775).  [PMID:31129216]
2. Ran Chen, Zhongwei An, Feng Li, Xinbing Chen, Pei Chen.  (2016)  Synthesis and physical properties of tolane liquid crystals containing 2,3-difluorophenylene and terminated by a tetrahydropyran moiety.  LIQUID CRYSTALS,      [PMID:] [10.1080/02678292.2015.1125959]

References

1. Z Szendi,F Sweet.  (1991-09-01)  Novel synthesis of cholesterol analogs: condensation of pregnenolone with dihydropyran or dihydrofuran..  Steroids,  56  ((9)): (458-463).  [PMID:1805457]
2. Weijun Yao,Lianjie Pan,Yihua Wu,Cheng Ma.  (2010-05-01)  Asymmetric synthesis of spiro-3,4-dihydropyrans via a domino organocatalytic sequence..  Organic letters,  12  ((10)): (2422-2425).  [PMID:20429598]
3. Yangbin Liu,Xiaohua Liu,Min Wang,Peng He,Lili Lin,Xiaoming Feng.  (2012-03-22)  Enantioselective synthesis of 3,4-dihydropyran derivatives via organocatalytic Michael reaction of α,β-unsaturated enones..  The Journal of organic chemistry,  77  ((8)): (4136-4142).  [PMID:22432769]
4. Quoc-Chon Le,Marie-Hélène Ropers,Hélène Terrisse,Bernard Humbert.  (2014-09-23)  Interactions between phospholipids and titanium dioxide particles..  Colloids and surfaces. B, Biointerfaces,  123  (150-157).  [PMID:25242734]
5. Vincent O Oninla,Bernadette Breiden,Jonathan O Babalola,Konrad Sandhoff.  (2014-10-24)  Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2..  Journal of lipid research,  55  ((12)): (2606-2619).  [PMID:25339683]
6. Yuan-Zhen Wu,Fu-Pu Lu,Hai-Lan Jiang,Cui-Ping Tan,Dong-Sheng Yao,Chun-Fang Xie,Da-Ling Liu.  (2014-12-24)  The furofuran-ring selectivity, hydrogen peroxide-production and low Km value are the three elements for highly effective detoxification of aflatoxin oxidase..  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,  76  (125-131).  [PMID:25533793]
7. Zhou-peng Li,Jing Li,Di Qu,Zheng Hou,Xiao-hui Yang,Zi-dan Zhang,Yu-kun Wang,Xiao-xing Luo,Ming-kai Li.  (2015-01-06)  Synthesis and pharmacological evaluations of 4-hydroxycoumarin derivatives as a new class of anti-Staphylococcus aureus agents..  The Journal of pharmacy and pharmacology,  67  ((4)): (573-582).  [PMID:25556550]
8. Li Zhang,Xin Luo,Zengyuan Niu,Xiwen Ye,Zhixu Tang,Peng Yao.  (2015-02-24)  Rapid screening and identification of multi-class substances of very high concern in textiles using liquid chromatography-hybrid linear ion trap orbitrap mass spectrometry..  Journal of chromatography. A,  1386  (22-30).  [PMID:25698382]
9. Joseph Aizen,Peter Thomas.  (2015-02-28)  Role of Pgrmc1 in estrogen maintenance of meiotic arrest in zebrafish oocytes through Gper/Egfr..  The Journal of endocrinology,  225  ((1)): (59-68).  [PMID:25720537]
10. Husam Aljwaid,Desley L White,Keith J Collard,A John Moody,Jonathan H Pinkney.  (2015-06-25)  Non-transferrin-bound iron is associated with biomarkers of oxidative stress, inflammation and endothelial dysfunction in type 2 diabetes..  Journal of diabetes and its complications,  29  ((7)): (943-949).  [PMID:26104728]
11. Shinji Takechi,Shigeru Ito,Nobuhiro Kashige,Takumi Ishida,Tadatoshi Yamaguchi.  (2015-07-15)  Identification of dihydropyrazine-glutathione adducts..  The Journal of toxicological sciences,  40  ((4)): (495-500).  [PMID:26165646]
12. Juan L Paris,M Victoria Cabañas,Miguel Manzano,María Vallet-Regí.  (2015-10-13)  Polymer-Grafted Mesoporous Silica Nanoparticles as Ultrasound-Responsive Drug Carriers..  ACS nano,  ((11)): (11023-11033).  [PMID:26456489]
13. Zachary C Kennedy,Carmen E Lisowski,Dumitru S Mitaru-Berceanu,James E Hutchison.  (2015-10-27)  Influence of Ligand Shell Composition upon Interparticle Interactions in Multifunctional Nanoparticles..  Langmuir : the ACS journal of surfaces and colloids,  31  ((46)): (12742-12752).  [PMID:26497061]
14. Fernando Campanhã Vicentini,Lívia L C Garcia,Luiz C S Figueiredo-Filho,Bruno C Janegitz,Orlando Fatibello-Filho.  (2016-02-02)  A biosensor based on gold nanoparticles, dihexadecylphosphate, and tyrosinase for the determination of catechol in natural water..  Enzyme and microbial technology,  84  (17-23).  [PMID:26827770]
15. Akane Hagiwara,Katsueki Ogiwara,Takayuki Takahashi.  (2016-02-09)  Expression of Membrane Progestin Receptors (mPRs) in Granulosa Cells of Medaka Preovulatory Follicles..  Zoological science,  33  ((1)): (98-105).  [PMID:26853875]
16. Ann P Murchison,David S Friedman,Emily W Gower,Julia A Haller,Byron L Lam,David J Lee,Gerald McGwin,Cynthia Owsley,Jinan Saaddine,Insight Study Group.  (2016-03-08)  A Multi-Center Diabetes Eye Screening Study in Community Settings: Study Design and Methodology..  Ophthalmic epidemiology,  23  ((2)): (109-115).  [PMID:26949832]
17. Shogo Higaki,Manami Shimada,Kazuaki Kawamoto,Takaaki Todo,Toshihiro Kawasaki,Ikuo Tooyama,Yasuhiro Fujioka,Noriyoshi Sakai,Tatsuyuki Takada.  (2017-02-18)  In vitro differentiation of fertile sperm from cryopreserved spermatogonia of the endangered endemic cyprinid honmoroko (Gnathopogon caerulescens)..  Scientific reports,  (42852-42852).  [PMID:28211534]
18. Xiaojie Duan,Zhengqiang Jiang,Yu Liu,Qiaojuan Yan,Man Xiang,Shaoqing Yang.  (2019-05-28)  High-level expression of codon-optimized Thielavia terrestris cutinase suitable for ester biosynthesis and biodegradation..  International journal of biological macromolecules,  135  (768-775).  [PMID:31129216]
19. Debendra K Mohapatra,Eswar Bhimireddy,P Sivarama Krishnarao,Pragna P Das,J S Yadav.  (2011-01-11)  Iodo-cyclizations: novel strategy for the total syntheses of polyrhacitide A and epi-cryptocaryolone..  Organic letters,  13  ((4)): (744-747).  [PMID:21214256]
20. Soha Jeon,Cha Young Yoo,Soo Nam Park.  (2015-03-31)  Improved stability and skin permeability of sodium hyaluronate-chitosan multilayered liposomes by Layer-by-Layer electrostatic deposition for quercetin delivery..  Colloids and surfaces. B, Biointerfaces,  129  (7-14).  [PMID:25819360]
21. O Kenrik Duru,Norman Turk,Susan L Ettner,Romain Neugebauer,Tannaz Moin,Jinnan Li,Lindsay Kimbro,Charles Chan,Robert H Luchs,Abigail M Keckhafer,Anya Kirvan,Sam Ho,Carol M Mangione.  (2015-05-07)  Adherence to Metformin, Statins, and ACE/ARBs Within the Diabetes Health Plan (DHP)..  Journal of general internal medicine,  30  ((11)): (1645-1650).  [PMID:25944019]
22. Tatsuya Higashi,Naoto Aiba,Tomoya Tanaka,Kazumi Yoshizawa,Shoujiro Ogawa.  (2015-09-12)  Methods for differential and quantitative analyses of brain neurosteroid levels by LC/MS/MS with ESI-enhancing and isotope-coded derivatization..  Journal of pharmaceutical and biomedical analysis,  117  (155-162).  [PMID:26355769]
23. Christoffer Rozenfeld,Ian A E Butts,Jonna Tomkiewicz,Jose-Luis Zambonino-Infante,David Mazurais.  (2015-09-30)  Abundance of specific mRNA transcripts impacts hatching success in European eel, Anguilla anguilla L..  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology,  191  (59-65).  [PMID:26415730]
24. Chieko Mitaka,Takahiro Masuda,Koji Kido,Tokujiro Uchida,Shinya Abe,Taku Miyasho,Makoto Tomita,Eiichi Inada.  (2016-02-07)  Polymyxin B hemoperfusion prevents acute kidney injury in sepsis model..  The Journal of surgical research,  201  ((1)): (59-68).  [PMID:26850185]
25. Cuili Wang,Dongteng Liu,Weiting Chen,Wei Ge,Wanshu Hong,Yong Zhu,Shi X Chen.  (2016-04-27)  Progestin increases the expression of gonadotropins in pituitaries of male zebrafish..  The Journal of endocrinology,  230  ((1)): (143-156).  [PMID:27113852]
26. Christiaan Jardínez,Alberto Vela,Julián Cruz-Borbolla,Rodrigo J Alvarez-Mendez,José G Alvarado-Rodríguez.  (2016-11-28)  Reduced density gradient as a novel approach for estimating QSAR descriptors, and its application to 1, 4-dihydropyridine derivatives with potential antihypertensive effects..  Journal of molecular modeling,  22  ((12)): (296-296).  [PMID:27889884]
27. Ran Chen, Zhongwei An, Feng Li, Xinbing Chen, Pei Chen.  (2016)  Synthesis and physical properties of tolane liquid crystals containing 2,3-difluorophenylene and terminated by a tetrahydropyran moiety.  LIQUID CRYSTALS,      [PMID:] [10.1080/02678292.2015.1125959]

Solution Calculators