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3,4-Dihydroxy-D-phenylalanine - ≥98.0%, high purity , CAS No.5796-17-8

5 Citations

≥98%

CAS#: 5796-17-8
Formula: C₉H₁₁NO₄
Molecular Weight: 197.19
Beilstein Registry Number: 2417637
EC Number: 227-343-0
MDL number: MFCD00063061
PubChem CID: 92222
PubChem SID: 488186694

Item Number

D113507

Grouped product items
SKU	Size	Availability	Price
D113507-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$87.90
D113507-100mg	100mg	In stock	$139.90
D113507-250mg	250mg	In stock	$249.90
D113507-1g	1g	In stock	$699.90

Basic Description

Synonyms	D-DOPA \| DOPA D-FORM [MI] \| Alanine, 3- (3,4-dihydroxyphenyl)-, D- \| AMY22155 \| D-3-(3,4-Dihydroxyphenyl)alanine \| ACETAMIDE,N-(2-HYDROXY-5-NITROPHENYL)- \| 3-Hydroxy-D-tyrosine \| AKOS016843249 \| BDBM500011 \| D-Dopa \| (R)-2-Amino-3-(3,4-dihydroxyphenyl)pro
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	3,4-Dihydroxy-D-phenylalanine is a DOPA enantiomer that lacks biological activity. DOPA enantiomer that lacks biological activity.

Associated Targets(Human)

POLB Tchem DNA polymerase beta (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA5A Tclin Carbonic anhydrase 5A, mitochondrial (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

POLH Tchem DNA polymerase eta (0 Activities)

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RUNX1 Tbio Runt-related transcription factor 1 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

POLI Tchem DNA polymerase iota (0 Activities)

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RECQL Tbio ATP-dependent DNA helicase Q1 (0 Activities)

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MPHOSPH8 Tbio M-phase phosphoprotein 8 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA5B Tclin Carbonic anhydrase 5B, mitochondrial (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA6 Tclin Carbonic anhydrase 6 (0 Activities)

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CA13 Tclin Carbonic anhydrase 13 (0 Activities)

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CA1 Tclin Carbonic anhydrase 1 (0 Activities)

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CA3 Tclin Carbonic anhydrase 3 (0 Activities)

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CA2 Tclin Carbonic anhydrase 2 (0 Activities)

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CA4 Tclin Carbonic anhydrase 4 (0 Activities)

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CA12 Tclin Carbonic anhydrase 12 (0 Activities)

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CA14 Tclin Carbonic anhydrase 14 (0 Activities)

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CA9 Tclin Carbonic anhydrase 9 (0 Activities)

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CA7 Tclin Carbonic anhydrase 7 (0 Activities)

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BLM Tchem Bloom syndrome protein (0 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (0 Activities)

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ALDH1A1 Tchem Retinal dehydrogenase 1 (0 Activities)

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THRB Tclin Thyroid hormone receptor beta (0 Activities)

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MAPT Tclin Microtubule-associated protein tau (0 Activities)

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HTT Tchem Huntingtin (0 Activities)

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NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)

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KDM4E Tchem Lysine-specific demethylase 4E (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA2 Tclin Carbonic anhydrase II (17698 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA3 Tclin Carbonic anhydrase III (753 Activities)

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CA6 Tclin Carbonic anhydrase VI (993 Activities)

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CA1 Tclin Carbonic anhydrase I (13240 Activities)

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POLB Tchem DNA polymerase beta (23632 Activities)

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CA5B Tclin Carbonic anhydrase VB (957 Activities)

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CA5A Tclin Carbonic anhydrase VA (1168 Activities)

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CA14 Tclin Carbonic anhydrase XIV (1305 Activities)

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

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CA12 Tclin Carbonic anhydrase XII (6231 Activities)

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CA9 Tclin Carbonic anhydrase IX (8255 Activities)

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HEK293 (82097 Activities)

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POLI Tchem DNA polymerase iota (116820 Activities)

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POLH Tchem DNA polymerase eta (21678 Activities)

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HTT Tchem Huntingtin (19182 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BLM Tchem Bloom syndrome protein (4248 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MPHOSPH8 Tbio M-phase phosphoprotein 8 (656 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Ca7 Carbonic anhydrase VII (3 Activities)

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Ca13 Carbonic anhydrase XIII (322 Activities)

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CA4 Carbonic anhydrase IV (1713 Activities)

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Carbonic anhydrase (69 Activities)

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Ca15 Carbonic anhydrase 15 (173 Activities)

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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapt Microtubule-associated protein tau (6 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

nfo Endonuclease 4 (425 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CAN2 Carbonic anhydrase 2 (140 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488186694
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488186694
IUPAC Name	(2R)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
INCHI	InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m1/s1
InChi Key	WTDRDQBEARUVNC-ZCFIWIBFSA-N
Canonical SMILES	C1=CC(=C(C=C1CC(C(=O)O)N)O)O
Isomeric SMILES	C1=CC(=C(C=C1C[C@H](C(=O)O)N)O)O
WGK Germany	3
PubChem CID	92222
Molecular Weight	197.19
Beilstein	2417637

Certificates

Certificate of Analysis(COA)

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16 results found

Lot Number	Certificate Type	Date	Item
J2410684	Certificate of Analysis	Jul 01, 2024	D113507
F2018017	Certificate of Analysis	Apr 03, 2024	D113507
I2328386	Certificate of Analysis	Sep 18, 2023	D113507
I2328387	Certificate of Analysis	Sep 18, 2023	D113507
I2328389	Certificate of Analysis	Sep 18, 2023	D113507
K2425017	Certificate of Analysis	Sep 18, 2023	D113507
L2402050	Certificate of Analysis	Sep 18, 2023	D113507
C2304464	Certificate of Analysis	Dec 08, 2022	D113507
C2304467	Certificate of Analysis	Dec 08, 2022	D113507
C2304563	Certificate of Analysis	Dec 08, 2022	D113507
C2304570	Certificate of Analysis	Dec 08, 2022	D113507
K2315076	Certificate of Analysis	Dec 08, 2022	D113507
F2309070	Certificate of Analysis	Jul 21, 2022	D113507
I2203159	Certificate of Analysis	Jul 21, 2022	D113507
I2203160	Certificate of Analysis	Jul 21, 2022	D113507
I2203295	Certificate of Analysis	Jul 21, 2022	D113507

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Chemical and Physical Properties

Solubility	Soluble in Chloroform and 1M Hydrochloric Acid,
Sensitivity	light sensitive
Melt Point(°C)	276-278℃

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Tian Lin, Cheng Cheng, Zhao Zhenwen, Liu Wei, Qi Li. (2023) Colorimetric Recognition of 3,4-Dihydroxy-D,L-phenylalanine with Tetrapeptide-modified Copper Nanoparticles as Chiral Nanozymes. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 39 (6): (1092-1099). [PMID:11848474] [10.1007/s40242-023-3193-z]
2. Xiaoyong Yue, Liguang Xu, Hengwei Lin, Chuanlai Xu, Si Li. (2023) Construction of Pt/Pt-Au doped chiral nanostructures using arginine and porphyrin assemblies as templates for enantioselective photocatalysis. Science Bulletin, 68 (1764). [PMID:37487791] [10.1016/j.scib.2023.07.021]
3. Xiaohui Niu, Simeng Yan, Jinliang Chen, Hongxia Li, Kunjie Wang. (2022) Enantioselective recognition of L/D-amino acids in the chiral nanochannels of a metal-organic framework. ELECTROCHIMICA ACTA, 405 (139809). [PMID:] [10.1016/j.electacta.2021.139809]
4. Xiaofeng Wei, Lishang Li, Huiting Lian, Xuegong Cao, Bin Liu. (2021) Grain-like chiral metal-organic framework/multi-walled carbon nanotube composited electrosensing interface for enantiorecognition of Tryptophan. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 886 (115108). [PMID:] [10.1016/j.jelechem.2021.115108]
5. Lu Lin, Hui-Ting Lian, Xiang-Ying Sun, Ya-Ming Yu, Bin Liu. (2015) An L-dopa electrochemical sensor based on a graphene doped molecularly imprinted chitosan film. Analytical Methods, 7 (4): (1387-1394). [PMID:] [10.1039/C4AY02524E]

References

1. Tian Lin, Cheng Cheng, Zhao Zhenwen, Liu Wei, Qi Li. (2023) Colorimetric Recognition of 3,4-Dihydroxy-D,L-phenylalanine with Tetrapeptide-modified Copper Nanoparticles as Chiral Nanozymes. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 39 (6): (1092-1099). [PMID:11848474] [10.1007/s40242-023-3193-z]
2. Xiaoyong Yue, Liguang Xu, Hengwei Lin, Chuanlai Xu, Si Li. (2023) Construction of Pt/Pt-Au doped chiral nanostructures using arginine and porphyrin assemblies as templates for enantioselective photocatalysis. Science Bulletin, 68 (1764). [PMID:37487791] [10.1016/j.scib.2023.07.021]
3. Xiaohui Niu, Simeng Yan, Jinliang Chen, Hongxia Li, Kunjie Wang. (2022) Enantioselective recognition of L/D-amino acids in the chiral nanochannels of a metal-organic framework. ELECTROCHIMICA ACTA, 405 (139809). [PMID:] [10.1016/j.electacta.2021.139809]
4. Xiaofeng Wei, Lishang Li, Huiting Lian, Xuegong Cao, Bin Liu. (2021) Grain-like chiral metal-organic framework/multi-walled carbon nanotube composited electrosensing interface for enantiorecognition of Tryptophan. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 886 (115108). [PMID:] [10.1016/j.jelechem.2021.115108]
5. Lu Lin, Hui-Ting Lian, Xiang-Ying Sun, Ya-Ming Yu, Bin Liu. (2015) An L-dopa electrochemical sensor based on a graphene doped molecularly imprinted chitosan film. Analytical Methods, 7 (4): (1387-1394). [PMID:] [10.1039/C4AY02524E]

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