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SKU | Size | Availability | Price | Qty |
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D650271-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $75.90 | |
D650271-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $120.90 | |
D650271-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $260.90 | |
D650271-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $410.90 |
Synonyms | 2-(3,4-dihydroxyphenyl)-3-hydroxy-4H-chromen-4-one | MFCD00189455 | 3',4'-Dihydroxyflavonol, >=98% (HPLC) | Fenyl-beta-naftylamin | 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-hydroxy- | Z2216891757 | DALAPON 2-(2,4,5-TRICHLOROPHENOXY)ETHYL ESTER | 3 |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | 3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide ( NO ) function in diabetic rat mesenteric arteries. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | 3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide ( NO ) function in diabetic rat mesenteric arteries. In Vitro 3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca ²⁺ desensitization in permeabilized third-order branches of rat mesenteric arteries. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-(3,4-dihydroxyphenyl)-3-hydroxychromen-4-one |
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INCHI | InChI=1S/C15H10O5/c16-10-6-5-8(7-11(10)17)15-14(19)13(18)9-3-1-2-4-12(9)20-15/h1-7,16-17,19H |
InChi Key | KPGMHZQXQVDYNT-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C2C(=C1)C(=O)C(=C(O2)C3=CC(=C(C=C3)O)O)O |
Isomeric SMILES | C1=CC=C2C(=C1)C(=O)C(=C(O2)C3=CC(=C(C=C3)O)O)O |
WGK Germany | 3 |
PubChem CID | 145826 |
Molecular Weight | 270.24 |
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Solubility | DMSO : 125 mg/mL (462.55 mM; Need ultrasonic) |
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Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed |
Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
WGK Germany | 3 |
RIDADR | UN28116.1/PGIII |