Grouped product items

SKU

Size

Availability

Price

Qty

D348811-10mg

10mg

In stock

$46.90

D348811-25mg

25mg

In stock

$89.90

D348811-100mg

100mg

Available within 4-8 weeks(?)

$357.90

Basic Description

Synonyms	4H-1-Benzopyran-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy- \| AC-34037 \| CS-0022554 \| Eupatorin, analytical standard \| Eupatorine \| KLAOKWJLUQKWIF-UHFFFAOYSA-N \| NCGC00180598-03 \| HMS3262O20 \| Eupatorin - 94% \| KBio2_004085 \| SCHEMBL5555
Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	Eupatorin acts as an antiproliferative in cells expressing the CYP1A- family. It induces G2/M block follow by apoptosis in cells expressing the CYP1A- family. It also functions as an anti-inflammatory.
Storage Temp	Store at 2-8°C,Protected from light
Shipped In	Wet ice
Product Description	Application： 3',5-Dihydroxy-4',6,7-trimethoxyflavone is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.

Associated Targets(Human)

CYP1B1 Tchem Cytochrome P450 1B1 (2 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1A1 Tchem Cytochrome P450 1A1 (1 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1B1 Tchem Cytochrome P450 1B1 (1148 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AURKB Tchem Serine/threonine-protein kinase Aurora-B (6805 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A1 Tchem Cytochrome P450 1A1 (1169 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FLT3 Tclin Tyrosine-protein kinase receptor FLT3 (13481 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HT-1080 (3966 Activities)

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K562 (73714 Activities)

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MCF7 (126967 Activities)

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MDA-MB-468 (9477 Activities)

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PC-3 (62116 Activities)

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SK-LU-1 (435 Activities)

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U-251 (51189 Activities)

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Monocyte (474 Activities)

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KB (17409 Activities)

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HeLa (62764 Activities)

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HCT-15 (51914 Activities)

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Enterococcus durans (113 Activities)

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Staphylococcus aureus (210822 Activities)

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Staphylococcus epidermidis (22802 Activities)

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Staphylococcus haemolyticus (1695 Activities)

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Staphylococcus hominis (482 Activities)

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Escherichia coli (133304 Activities)

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Staphylococcus simulans (400 Activities)

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Staphylococcus warneri (476 Activities)

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Enterococcus faecium (13803 Activities)

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Bacillus subtilis (32866 Activities)

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Enterococcus faecalis (29875 Activities)

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Staphylococcus saprophyticus (562 Activities)

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Staphylococcus capitis (242 Activities)

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Enterococcus avium (81 Activities)

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Enterococcus gallinarum (172 Activities)

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Staphylococcus lugdunensis (349 Activities)

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Enterococcus casseliflavus (94 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxychromen-4-one
INCHI	InChI=1S/C18H16O7/c1-22-12-5-4-9(6-10(12)19)13-7-11(20)16-14(25-13)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3
InChi Key	KLAOKWJLUQKWIF-UHFFFAOYSA-N
Canonical SMILES	COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)O)O
Isomeric SMILES	COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)O)O
WGK Germany	1
PubChem CID	97214
Molecular Weight	344.32

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
J2331207	Certificate of Analysis	Sep 23, 2023	D348811
J2331208	Certificate of Analysis	Sep 23, 2023	D348811
J2331209	Certificate of Analysis	Sep 23, 2023	D348811
J2331399	Certificate of Analysis	Sep 23, 2023	D348811
J2331407	Certificate of Analysis	Sep 23, 2023	D348811

Chemical and Physical Properties

Solubility	Insoluble in water. Soluble in chloroform and methanol.
Sensitivity	Light sensitive；Heat sensitive
Melt Point(°C)	188-197℃

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	1
RIDADR	UN28116.1/PGIII

Solution Calculators

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3′,5-Dihydroxy-4′,6,7-trimethoxyflavone - 97%, high purity , CAS No.855-96-9

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator