Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | 3,5-DIHYDROXYBENZOIC ACID | 99-10-5 | alpha-Resorcylic acid | 5-Carboxyresorcinol | Benzoic acid, 3,5-dihydroxy- | 3,5-Dihydroxybenzoicacid | 3,5-Dihydroxy-benzoic acid | 3,5-DIHYDROXYBENZOATE | NSC 22948 | 3,5-DHBA | .alpha.-Resorcylic acid | a-resorcylic acid | 3,5-Dihydroxy b |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
Associated Targets(Human)
CA1 Tclin Carbonic anhydrase 1 (1 Activities)
CA2 Tclin Carbonic anhydrase 2 (1 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
CA14 Tclin Carbonic anhydrase 14 (1 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HCAR1 Tchem Hydroxycarboxylic acid receptor 1 (2 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
CA2 Tclin Carbonic anhydrase II (17698 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CA1 Tclin Carbonic anhydrase I (13240 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ALB Tchem Serum albumin (2651 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CA14 Tclin Carbonic anhydrase XIV (1305 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
TLR2 Tchem Toll-like receptor 2 (975 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HCAR1 Tchem G-protein coupled receptor 81 (382 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
Ca7 Carbonic anhydrase VII (3 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Hcar2 Hydroxycarboxylic acid receptor 2 (55 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Carbonic anhydrase (69 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Saccharomyces cerevisiae (19171 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 3,5-dihydroxybenzoic acid |
|---|---|
| INCHI | InChI=1S/C7H6O4/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,8-9H,(H,10,11) |
| InChi Key | UYEMGAFJOZZIFP-UHFFFAOYSA-N |
| Canonical SMILES | C1=C(C=C(C=C1O)O)C(=O)O |
| Isomeric SMILES | C1=C(C=C(C=C1O)O)C(=O)O |
| WGK Germany | 1 |
| RTECS | VH3708000 |
| PubChem CID | 7424 |
| Molecular Weight | 154.12 |
| Beilstein | 2207864 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Sensitivity | Light sensitive. |
|---|---|
| Flash Point(°F) | 392 °F |
| Flash Point(°C) | ≥200℃ |
| Melt Point(°C) | 232-233°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 1 |
| RTECS | VH3708000 |
Related Documents
Citations of This Product
| 1. Dali Fu, Haodong Wang, Tan Wang, Chunming Xu, Yehua Han. (2023) Structural insights into variation of intramolecular acid site using phase transition experiments and computation. AICHE JOURNAL, 70 (4): (e18342). [PMID:] [10.1002/aic.18342] |
| 2. Diqin Zhang, Yu Zhao, Bin Guo, Zhen Zhang, Dejiao Hu, Zhen Wang, Jianhua Zhu, Yan Ye, Yuxia Zhao. (2023) Acrylate dendritic monomers for fabricating holographic data storage media with high performance. EUROPEAN POLYMER JOURNAL, 198 (112436). [PMID:21418524] [10.1016/j.eurpolymj.2023.112436] |
| 3. Hui Yang, Guoming Yuan, Enxiang Jiao, Kunxin Wang, WenJie Diao, Zhao Li, Kun Wu, Jun Shi. (2023) Low dielectric constant and high thermal stability of liquid crystal epoxy polymers based on functionalized poly(phenylene oxide). EUROPEAN POLYMER JOURNAL, 198 (112378). [PMID:] [10.1016/j.eurpolymj.2023.112378] |
| 4. Jian Yao, Lun Gui, Qizhang Long. (2022) A chlorogenic acid esterase from a metagenomic library with unique substrate specificity and its application in caffeic and ferulic acid production from agricultural byproducts. BIOCATALYSIS AND BIOTRANSFORMATION, [PMID:] [10.1080/10242422.2021.1969370] |
| 5. Qiqin Wang, Lingjue Sun, Huihui Wu, Ning Deng, Xianglong Zhao, Jingwei Zhou, Tingting Zhang, Hai Han, Zhengjin Jiang. (2022) Rapid fabrication of zwitterionic sulfobetaine vinylimidazole-based monoliths via photoinitiated copolymerization for hydrophilic interaction chromatography. Journal of Pharmaceutical Analysis, 12 (783). [PMID:36320596] [10.1016/j.jpha.2022.05.008] |
| 6. Guojia Yu, Xinjian Chen, Lichao He, Xiangrong Li, Zhiyong Zhou, Zhongqi Ren. (2021) Study on the solubilization of telmisartan by forming cocrystals with aromatic carboxylic acids. CRYSTENGCOMM, 23 (27): (4871-4878). [PMID:] [10.1039/D1CE00551K] |
| 7. Lu Wang, Ke Jing, Baowei Hu, Junhe Lu. (2021) Hydrogen peroxide suppresses the formation of brominated oxidation by-products in heat-activated peroxydisulfate oxidation process. CHEMICAL ENGINEERING JOURNAL, 417 (129138). [PMID:] [10.1016/j.cej.2021.129138] |
| 8. Shiyun Tang, Yuanxing Duan, Feng Chang, Wei Jiang, Fengmei Zhang, Zhihua Liu, Yuting Yang, Chunbo Liu, Yingzhuang Chen. (2020) The fabrication of carboxylic acid-functionalized porous layer open tube column and its application in hydrophilic interaction chromatography for small polar molecules. JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, [PMID:] [10.1080/10826076.2020.1848864] |
| 9. Bingya Chen, Chenyang Zhang, Yanmei Zhao, Dongsheng Wang, Gregory V. Korshin, Jinren Ni, Mingquan Yan. (2020) Interpreting main features of the differential absorbance spectra of chlorinated natural organic matter: Comparison of the experimental and theoretical spectra of model compounds. WATER RESEARCH, 185 (116206). [PMID:32736281] [10.1016/j.watres.2020.116206] |
| 10. Ma Mingxuan, Du Yingxiang, Zhang Liu, Gan Jie, Yang Jiangxia. (2020) β-Cyclodextrin covalent organic framework–modified organic polymer monolith as a stationary phase for combined hydrophilic and hydrophobic aqueous capillary electrochromatographic separation of small molecules. MICROCHIMICA ACTA, 187 (7): (1-11). [PMID:32533434] [10.1007/s00604-020-04360-1] |
| 11. Ke Jing, Deyang Kong, Junhe Lu. (2020) Change of disinfection byproducts formation potential of natural organic matter after exposure to persulphate and bicarbonate. WATER RESEARCH, 182 (115970). [PMID:32679387] [10.1016/j.watres.2020.115970] |
| 12. Qiqin Wang, Kun Peng, Ning Gan, Xiao Liu, Hao Huang, Huikai Shao, Hanying Jin, Jacques Crommen, Zhengjin Jiang. (2020) Rapid fabrication of versatile zwitterionic super-hydrophilic polymers by sole-monomer system for biomolecules separation. CHEMICAL ENGINEERING JOURNAL, 396 (125121). [PMID:] [10.1016/j.cej.2020.125121] |
| 13. Qiqin Wang, Qiaoxuan Zhang, Hao Huang, Pengwei Zhao, Lingjue Sun, Kun Peng, Xiao Liu, Meng Ruan, Huikai Shao, Jacques Crommen, Pei Yu, Zhengjin Jiang. (2020) Fabrication and application of zwitterionic phosphorylcholine functionalized monoliths with different hydrophilic crosslinkers in hydrophilic interaction chromatography. ANALYTICA CHIMICA ACTA, 1101 (222). [PMID:32029114] [10.1016/j.aca.2019.12.016] |
| 14. Qian Tao, Qian-Qian Hao, Alexander P. Voronin, Xia-Lin Dai, Yu Huang, German L. Perlovich, Tong-Bu Lu, Jia-Mei Chen. (2019) Polymorphic Forms of a Molecular Salt of Phenazopyridine with 3,5-Dihydroxybenzoic Acid: Crystal Structures, Theoretical Calculations, Thermodynamic Stability, and Solubility Aspects. CRYSTAL GROWTH & DESIGN, 19 (10): (5636–5647). [PMID:] [10.1021/acs.cgd.9b00618] |
| 15. Wang Lu, Ji Yuefei, Lu Junhe, Kong Deyang, Yin Xiaoming, Zhou Quansuo. (2017) Comparative study of the formation of brominated disinfection byproducts in UV/persulfate and UV/H2O2 oxidation processes in the presence of bromide. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 24 (29): (23219-23225). [PMID:28831656] [10.1007/s11356-017-9935-z] |
| 16. Rongbin Huang, Lei Xiang, Ying Liu, Xiangping Deng, Xuan Cao, Lanfang Li, Cuiyun Yu, Yanming Chen, Guotao Tang. (2016) Synthesis and in vitro evaluation of pH-sensitive PEG-I-dC16 block polymer micelles for anticancer drug delivery. JOURNAL OF PHARMACY AND PHARMACOLOGY, 68 (6): (751-761). [PMID:27018539] [10.1111/jphp.12545] |
| 17. Xiaoming Zhang, Fuxing Sun, Tingting Zhang, Jiangtao Jia, Hongmin Su, Chenhui Wang, Guangshan Zhu. (2015) Three pharmaceuticals cocrystals of adefovir: Syntheses, structures and dissolution study. JOURNAL OF MOLECULAR STRUCTURE, 1100 (395). [PMID:] [10.1016/j.molstruc.2015.07.033] |
| 18. Jia-Mei Chen, Song Li, Tong-Bu Lu. (2014) Pharmaceutical Cocrystals of Ribavirin with Reduced Release Rates. CRYSTAL GROWTH & DESIGN, 14 (12): (6399–6408). [PMID:] [10.1021/cg501247x] |
| 19. Jia-Xi Song, Yan Yan, Jia Yao, Jia-Mei Chen, Tong-Bu Lu. (2014) Improving the Solubility of Lenalidomide via Cocrystals. CRYSTAL GROWTH & DESIGN, 14 (6): (3069–3077). [PMID:] [10.1021/cg500327s] |
| 20. Guangxin Yuan, Yongbo Peng, Zhenghua Liu, Jieya Hong, Yao Xiao, Jialiang Guo, Norman W. Smith, Jacques Crommen, Zhengjin Jiang. (2013) A facile and efficient strategy to enhance hydrophilicity of zwitterionic sulfoalkylbetaine type monoliths. JOURNAL OF CHROMATOGRAPHY A, 1301 (88). [PMID:23796416] [10.1016/j.chroma.2013.05.063] |
| 21. Zhenghua Liu, Yongbo Peng, Tingting Wang, Guangxin Yuan, Qiaoxuan Zhang, Jialiang Guo, Zhengjin Jiang. (2012) Preparation and application of novel zwitterionic monolithic column for hydrophilic interaction chromatography. JOURNAL OF SEPARATION SCIENCE, 36 (2): (262-269). [PMID:23180752] [10.1002/jssc.201200682] |
References
| 1. Dali Fu, Haodong Wang, Tan Wang, Chunming Xu, Yehua Han. (2023) Structural insights into variation of intramolecular acid site using phase transition experiments and computation. AICHE JOURNAL, 70 (4): (e18342). [PMID:] [10.1002/aic.18342] |
| 2. Diqin Zhang, Yu Zhao, Bin Guo, Zhen Zhang, Dejiao Hu, Zhen Wang, Jianhua Zhu, Yan Ye, Yuxia Zhao. (2023) Acrylate dendritic monomers for fabricating holographic data storage media with high performance. EUROPEAN POLYMER JOURNAL, 198 (112436). [PMID:21418524] [10.1016/j.eurpolymj.2023.112436] |
| 3. Hui Yang, Guoming Yuan, Enxiang Jiao, Kunxin Wang, WenJie Diao, Zhao Li, Kun Wu, Jun Shi. (2023) Low dielectric constant and high thermal stability of liquid crystal epoxy polymers based on functionalized poly(phenylene oxide). EUROPEAN POLYMER JOURNAL, 198 (112378). [PMID:] [10.1016/j.eurpolymj.2023.112378] |
| 4. Jian Yao, Lun Gui, Qizhang Long. (2022) A chlorogenic acid esterase from a metagenomic library with unique substrate specificity and its application in caffeic and ferulic acid production from agricultural byproducts. BIOCATALYSIS AND BIOTRANSFORMATION, [PMID:] [10.1080/10242422.2021.1969370] |
| 5. Qiqin Wang, Lingjue Sun, Huihui Wu, Ning Deng, Xianglong Zhao, Jingwei Zhou, Tingting Zhang, Hai Han, Zhengjin Jiang. (2022) Rapid fabrication of zwitterionic sulfobetaine vinylimidazole-based monoliths via photoinitiated copolymerization for hydrophilic interaction chromatography. Journal of Pharmaceutical Analysis, 12 (783). [PMID:36320596] [10.1016/j.jpha.2022.05.008] |
| 6. Guojia Yu, Xinjian Chen, Lichao He, Xiangrong Li, Zhiyong Zhou, Zhongqi Ren. (2021) Study on the solubilization of telmisartan by forming cocrystals with aromatic carboxylic acids. CRYSTENGCOMM, 23 (27): (4871-4878). [PMID:] [10.1039/D1CE00551K] |
| 7. Lu Wang, Ke Jing, Baowei Hu, Junhe Lu. (2021) Hydrogen peroxide suppresses the formation of brominated oxidation by-products in heat-activated peroxydisulfate oxidation process. CHEMICAL ENGINEERING JOURNAL, 417 (129138). [PMID:] [10.1016/j.cej.2021.129138] |
| 8. Shiyun Tang, Yuanxing Duan, Feng Chang, Wei Jiang, Fengmei Zhang, Zhihua Liu, Yuting Yang, Chunbo Liu, Yingzhuang Chen. (2020) The fabrication of carboxylic acid-functionalized porous layer open tube column and its application in hydrophilic interaction chromatography for small polar molecules. JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, [PMID:] [10.1080/10826076.2020.1848864] |
| 9. Bingya Chen, Chenyang Zhang, Yanmei Zhao, Dongsheng Wang, Gregory V. Korshin, Jinren Ni, Mingquan Yan. (2020) Interpreting main features of the differential absorbance spectra of chlorinated natural organic matter: Comparison of the experimental and theoretical spectra of model compounds. WATER RESEARCH, 185 (116206). [PMID:32736281] [10.1016/j.watres.2020.116206] |
| 10. Ma Mingxuan, Du Yingxiang, Zhang Liu, Gan Jie, Yang Jiangxia. (2020) β-Cyclodextrin covalent organic framework–modified organic polymer monolith as a stationary phase for combined hydrophilic and hydrophobic aqueous capillary electrochromatographic separation of small molecules. MICROCHIMICA ACTA, 187 (7): (1-11). [PMID:32533434] [10.1007/s00604-020-04360-1] |
| 11. Ke Jing, Deyang Kong, Junhe Lu. (2020) Change of disinfection byproducts formation potential of natural organic matter after exposure to persulphate and bicarbonate. WATER RESEARCH, 182 (115970). [PMID:32679387] [10.1016/j.watres.2020.115970] |
| 12. Qiqin Wang, Kun Peng, Ning Gan, Xiao Liu, Hao Huang, Huikai Shao, Hanying Jin, Jacques Crommen, Zhengjin Jiang. (2020) Rapid fabrication of versatile zwitterionic super-hydrophilic polymers by sole-monomer system for biomolecules separation. CHEMICAL ENGINEERING JOURNAL, 396 (125121). [PMID:] [10.1016/j.cej.2020.125121] |
| 13. Qiqin Wang, Qiaoxuan Zhang, Hao Huang, Pengwei Zhao, Lingjue Sun, Kun Peng, Xiao Liu, Meng Ruan, Huikai Shao, Jacques Crommen, Pei Yu, Zhengjin Jiang. (2020) Fabrication and application of zwitterionic phosphorylcholine functionalized monoliths with different hydrophilic crosslinkers in hydrophilic interaction chromatography. ANALYTICA CHIMICA ACTA, 1101 (222). [PMID:32029114] [10.1016/j.aca.2019.12.016] |
| 14. Qian Tao, Qian-Qian Hao, Alexander P. Voronin, Xia-Lin Dai, Yu Huang, German L. Perlovich, Tong-Bu Lu, Jia-Mei Chen. (2019) Polymorphic Forms of a Molecular Salt of Phenazopyridine with 3,5-Dihydroxybenzoic Acid: Crystal Structures, Theoretical Calculations, Thermodynamic Stability, and Solubility Aspects. CRYSTAL GROWTH & DESIGN, 19 (10): (5636–5647). [PMID:] [10.1021/acs.cgd.9b00618] |
| 15. Wang Lu, Ji Yuefei, Lu Junhe, Kong Deyang, Yin Xiaoming, Zhou Quansuo. (2017) Comparative study of the formation of brominated disinfection byproducts in UV/persulfate and UV/H2O2 oxidation processes in the presence of bromide. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 24 (29): (23219-23225). [PMID:28831656] [10.1007/s11356-017-9935-z] |
| 16. Rongbin Huang, Lei Xiang, Ying Liu, Xiangping Deng, Xuan Cao, Lanfang Li, Cuiyun Yu, Yanming Chen, Guotao Tang. (2016) Synthesis and in vitro evaluation of pH-sensitive PEG-I-dC16 block polymer micelles for anticancer drug delivery. JOURNAL OF PHARMACY AND PHARMACOLOGY, 68 (6): (751-761). [PMID:27018539] [10.1111/jphp.12545] |
| 17. Xiaoming Zhang, Fuxing Sun, Tingting Zhang, Jiangtao Jia, Hongmin Su, Chenhui Wang, Guangshan Zhu. (2015) Three pharmaceuticals cocrystals of adefovir: Syntheses, structures and dissolution study. JOURNAL OF MOLECULAR STRUCTURE, 1100 (395). [PMID:] [10.1016/j.molstruc.2015.07.033] |
| 18. Jia-Mei Chen, Song Li, Tong-Bu Lu. (2014) Pharmaceutical Cocrystals of Ribavirin with Reduced Release Rates. CRYSTAL GROWTH & DESIGN, 14 (12): (6399–6408). [PMID:] [10.1021/cg501247x] |
| 19. Jia-Xi Song, Yan Yan, Jia Yao, Jia-Mei Chen, Tong-Bu Lu. (2014) Improving the Solubility of Lenalidomide via Cocrystals. CRYSTAL GROWTH & DESIGN, 14 (6): (3069–3077). [PMID:] [10.1021/cg500327s] |
| 20. Guangxin Yuan, Yongbo Peng, Zhenghua Liu, Jieya Hong, Yao Xiao, Jialiang Guo, Norman W. Smith, Jacques Crommen, Zhengjin Jiang. (2013) A facile and efficient strategy to enhance hydrophilicity of zwitterionic sulfoalkylbetaine type monoliths. JOURNAL OF CHROMATOGRAPHY A, 1301 (88). [PMID:23796416] [10.1016/j.chroma.2013.05.063] |
| 21. Zhenghua Liu, Yongbo Peng, Tingting Wang, Guangxin Yuan, Qiaoxuan Zhang, Jialiang Guo, Zhengjin Jiang. (2012) Preparation and application of novel zwitterionic monolithic column for hydrophilic interaction chromatography. JOURNAL OF SEPARATION SCIENCE, 36 (2): (262-269). [PMID:23180752] [10.1002/jssc.201200682] |