3-amino-2-benzoyl-6-oxo-6H,7H-thieno[2,3-b]pyridine-5-carboxylic acid , CAS No.439946-22-2, Inhibitor of ubiquitin C-terminal hydrolase L1

Item Number
A358316
Grouped product items
SKUSizeAvailabilityPrice Qty
A358316-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$458.90
A358316-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$927.90

Basic Description

SynonymsLDN-91946 | 3-amino-2-benzoyl-6-oxo-6H,7H-thieno[2,3-b]pyridine-5-carboxylic acid | CHEMBL1190585 | 3-amino-2-benzoyl-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carboxylic acid | ChemDiv2_004146 | LDN 91946 | Oprea1_263045 | GTPL8661 | SCHEMBL20007095 | HMS1380M10 | BDBM503260
Specifications & PurityMoligand™
Storage TempRoom temperature
Shipped InNormal
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of ubiquitin C-terminal hydrolase L1

Associated Targets(Human)

UCHL1 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CASP3 Tchem Caspase-3 (3632 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TGM2 Tchem Protein-glutamine gamma-glutamyltransferase (1221 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP5 Tchem Ubiquitin carboxyl-terminal hydrolase 5 (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UCHL1 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L1 (107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UCHL3 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L3 (50 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Canonical SMILES C1=CC=C(C=C1)C(=O)C2=C(C3=C(S2)NC(=O)C(=C3)C(=O)O)N
Isomeric SMILES C1=CC=C(C=C1)C(=O)C2=C(C3=C(S2)NC(=O)C(=C3)C(=O)O)N
PubChem CID 950368
Molecular Weight 314.32

Certificates

Certificate of Analysis(COA)

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Related Documents

References

1. Mermerian AH, Case A, Stein RL, Cuny GD.  (2007)  Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors..  Bioorg Med Chem Lett,  17  (13): (3729-32).  [PMID:17449248]

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