Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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A423162-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 |
Nucleoside reverse-transcriptase inhibitor (NRTI)
Synonyms | zidovudine | Azidothymidine | 30516-87-1 | 3'-Azido-3'-deoxythymidine | Retrovir | AZT | Zidovudinum | Thymidine, 3'-azido-3'-deoxy- | Compound S | Zidovudina | ZIDOVUDINE [AZT] | zidovudin | Trizivir | BW A509U | Zidovudinum [Latin] | 3'-Deoxy-3'-azidothymidine | BWA509U | ZDV | BW-A509U | B |
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Specifications & Purity | Moligand™, 10mM in DMSO |
Biochemical and Physiological Mechanisms | Zidovudine (Azidothymidine, AZT) is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection.Nucleoside reverse-transcriptase inhibitor (NRTI). Antiretroviral, Blood brain barri |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Product Description | 3′-Azido-3′-deoxythymidine is an inhibitor of HIV-1 RT (HIV-1 reverse transcriptase) that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3′-Azido-3′-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione |
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INCHI | InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1 |
InChi Key | HBOMLICNUCNMMY-XLPZGREQSA-N |
Canonical SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-] |
Isomeric SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-] |
WGK Germany | 3 |
RTECS | XP2072000 |
PubChem CID | 35370 |
Molecular Weight | 267.24 |
Beilstein | 3595791 |
Reaxy-Rn | 3595791 |
Enter Lot Number to search for COA:
Sensitivity | Light Sensitive & Hygroscopic |
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Specific Rotation[α] | 47° (C=1,H2O) |
Melt Point(°C) | 124 °C |
Pictogram(s) | GHS08 |
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Signal | Danger |
Hazard Statements | H341:Suspected of causing genetic defects H351:Suspected of causing cancer H372:Causes damage to organs through prolonged or repeated exposure H350:May cause cancer H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P281:Use personal protective equipment as required. P270:Do not eat, drink or smoke when using this product. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | XP2072000 |
Reaxy-Rn | 3595791 |
Merck Index | 10123 |
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